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GI drugs
Drugs for gastrointestinal disorders
33
Veterinary Medicine
Undergraduate 2
11/08/2009

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Cards

Term
Emetics are drugs that__________
Definition
induce vomiting (Do not induce if petroleum products were ingested)
Term
CRTZ, what is it, and what 2 drugs are used to act on it?
Definition
Chenorecptor Trigger Zone, Apomorphine and Xylazine ( apomorphine use controversial in cats)
Term
Name 2 locally acting emetics.
Definition
Syrup of Ipecac (OTC product, caution with erratic heart condition)Hydrogen Peroxide (too much will burn esophageal tissues)
Term
Antiemetic drugs____________
Definition
Control or prevent vomiting
Term
Antiemetics are generally given_______(route)
Definition
parenterally (vomiting precludes oral route, pretty obvious)
Term
Name 3 antiemetic drugs.(Not antihistamines or anticholinergics)
Definition
Chlorpromazine (Thorazine)-more effective in dogs, reacts with other drugs, Prochlorperazine (Compazine)- motion sickness in dogs and cats, combined with anticholinergic, Metoclopramice (Reglan)- esspecially with Parvoviral enteristis and chemotherapy vomiting.
Term
Name three antihistamines used as antiemetics.
Definition
Trimethobenzamide (Tigan), Dimenhydrinate (Dramamine) and Diphenhydramine (Benadryl)
Term
Name two anticholinergics used as antiemetics.
Definition
Aminopentamide (Centrine) and Propantheline (Pro-Banthine)
Term
Reasons for gastric ulcers.
Definition
Stress, metobolic disease, drugs (esspecially corticosteroids), and gastric hyperacidity.
Term
Signs of gastric ulcers.
Definition
Anoresia, hematemesis, pain, melena
Term
How do H2 receptor antagonist help in the treatment of gastric ulcers?
Definition
They reduce the release of hydrochloric acid thus decreasing the errosion of the mucosa.
Term
Name the three H2 receptor antagonists used as antiulcer medications.
Definition
Cimetidine (Tagamet), Rantidine (Zantac), Famotidine (Pepcid)
Term
Which H2 receptor antagonist reacts with fewer drug interactions? Which has reduced frequency of dosing?
Definition
Famotidine (Pepcid), Rantidine (Zantac)
Term
Two antiulcer meds which are proton pump inhibitors.
Definition
Omeprazole (equine is Gatrogard, human prilosec), Lansoprazole
Term
Name two antacids used as antiulcer meds.
Definition
Aluminum/magnesium (Maalox, Mylanta) and Magnesium hydroxide (Milk of magnesia)
Term
Name the one gastromucosal protectant used in vet med.
Definition
Sucralfate (Carafate) - binds to gastric ulcers like bandaid
Term
Used to prevent or treat gastric ulcers associated with NSAIDs.
Definition
Misoprostol (Proglandin E-1 analog, prvents release of hydrogen ions into stomach)
Term
Antacids are______________
Definition
Non-absorbable salts used to decrease hydrochloric acid levels in the stomach.
Term
Name two opiates used to control diarrhea.
Definition
Diphenoxylate (Lomotil)-NOT for cats who'd have thunk,Loperamide (Imodium)-OK for cats
Term
Name 3 antispasmotics for diarrhea.
Definition
Amonopentamide (Centrine), Propantheline (Pro-Banthine), Methscopolamine (Pamine)
Term
Mucosal protectants used in diarrhea.
Definition
Bismuth subsalicylate (Pepto-Bismol)Also antibacterial, caution with....yeah, cats)Kaolin/pectin (Kaopectate), activated charcoal (in poisoning)
Term
What are cathartics?
Definition
Strong laxatives
Term
Saline/hyperosmotic agents hold water in the digestive tract to soften stool. Name some used in veterinary medicine.
Definition
Lactolose, Magnesium hydroxide (milk of magnesia), Magnesium sulfate (Epsom salts), sodium phosphate enemas (Fleet enemas,used in dogs, foals, but not...wait for it....Cats!)
Term
Bulk producing agents are indigestable plant material that acts by absorbing water. What are they used for? Name some.
Definition
To treat constipation and sand impactions in horses. Psyllium(Metamucil), bran,Equine psyllium, Equine laxative (Sand-Lax)
Term
Lubricants soften fecal masses for easier movement. Mineral oil is one, what is used for hairballs in cats?
Definition
Petrolatum (Laxatone, Laxaire)
Term
Name a stool softener used for hard dry feces in small animals, impaction in horses and sometimes digestive upsets in cattle.
Definition
Docusate (Colase), Disposoject enema
Term
Name some gatrointestinal stimulants used.
Definition
Metoclopramide (Reglan), Cisapride (Propulsid), erythromycin, Dexpanthenol (d-Pantenol)
Term
A product which contains pancreatic enzymes to aid in digestion of fats, protiens and carbohydrates.
Definition
Pancrelipase (V-powder, Viokase)
Term
Flagyl is a trade name for___________. It is an anti_____________and anti________
Definition
Metronidazole, bacterial, parasitic
Term
Name some antibiotics used in treating GI disorders.
Definition
Amoxicillin, cephalosporins, aminoglycosides,along with Metronidazole (Flagyl)for giardiasis, ulcerative colic and anerobic infections.(Flagyl not for pregnant or nursing)
Term
Name some anti-inflammatory agents for treatment of idiopathic inflammatory bowel disease
Definition
Predisone, azathioprine (Imuran), Sulfasalazine (Azulfidine), Asprin (use asprin with caution in,surprise surprise...cats)
Term
Name some antifoaming agent for ruminants.
Definition
Bloat Gard, Bloat treatment, Bloat-Pac, Therabloat
Term
Name a couple oral products from list in Wanamaker pg.168
Definition
Ora Vet(plaque prevention or oral sealer). Nolvadent (oral cleansing solution), C.E.T. enzamatic toothpaste.and others such as diets, chews, ect.
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