Term
| Can contribute to dental caries |
|
Definition
|
|
Term
| As people age total body water tends to decrease which can contribute to |
|
Definition
|
|
Term
| Common manifestations of ADRs in older people |
|
Definition
| confusion, lack of appetite, depression, ataxia |
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|
Term
| "Anti-turkey" (anticholinergic0 side effects include |
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Definition
|
|
Term
| the SAIL protocol includes |
|
Definition
| Simple, Adverse effects, Indication and List |
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|
Term
| When evaluating an 87 yr old pt and her drug regiment it is important to |
|
Definition
| know her relationship with her drugs |
|
|
Term
|
Definition
| reserve capacity decreases |
|
|
Term
| physiologic changes associated with aging inlucde |
|
Definition
| presbycusis, increased gastric pH, increased alpha1-acid glycoprotein, increased body fat |
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|
Term
| 40% who suffer from these are over 60 years of age |
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Definition
|
|
Term
|
Definition
| barbiturates, benzodiazepines |
|
|
Term
| total body water decreases |
|
Definition
| lithium, ethanol, diuretics |
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|
Term
|
Definition
|
|
Term
| plasma protein alterations |
|
Definition
| digoxin, theophylline, phenytoin, warfarin |
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|
Term
| Phase I (CYP460 metabolism): decreases with age |
|
Definition
|
|
Term
| Phase II (conjugation): metabolism; generally unaffected with age |
|
Definition
|
|
Term
|
Definition
| renal function generally decline with age, renal blood flow may decrease 40% |
|
|
Term
|
Definition
| not a good indicator of renal function in elders |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Benzodiazepines, Opiates, Warfarin, Anticholingerics |
|
|
Term
|
Definition
| Kidney, Liver, Brain, Intestines |
|
|
Term
|
Definition
| unnecessary drugs, drug-drug interactions, contraindicated |
|
|
Term
| Likelihood of 2 drugs used |
|
Definition
|
|
Term
| likelihood of 5 drugs used |
|
Definition
|
|
Term
| likelihood of 8 drugs used |
|
Definition
|
|
Term
|
Definition
| indication without drug, wrong drug, too much/too little drug, innnappropiate/bad drug, drug/something interaction, compliance/adherence, iatrogenic/caused by our "care" |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| anticholinergics, benzodiazepines |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| antihistamines, benzodiazepines |
|
|
Term
|
Definition
| benzodiazepines, blood pressure drugs |
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Has been found to significantly impair memory. the behavioral effects appear dose related and include restlessness, agitation, irritability, negativism, and hallucinations |
|
Definition
|
|
Term
| Anti-ACh medications may produce cognitive impairment (Reserve Capacity) |
|
Definition
| in a dose-dependent fashion |
|
|
Term
|
Definition
| miosis, salivation, active GI motility, urination, bardycardia, bronchoconstriction |
|
|
Term
|
Definition
| mydriasis, xerostomia, constipation, urinary retention, tachycardia, bronchodilation |
|
|
Term
| Acetylcholinesterase inhibitors (Turkey drugs) |
|
Definition
|
|
Term
| Anticholinergics (Anti-Turkey) |
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Definition
|
|
Term
| Effects of Atropine: 0.5 mg |
|
Definition
| slight cardiac slowing, xerostomia, inhibits sweating |
|
|
Term
| Effects of Atropine: 1 mg |
|
Definition
| xerostomia, thirst, acceleration of heart, mild dilation of pupils (mydriasis) |
|
|
Term
| effects of Atropine: 2 mg |
|
Definition
| rapid heart rate, dilated pupils |
|
|
Term
| effects of Atropine: 5 mg |
|
Definition
| difficulty speaking/swallowing, restlessness, fatigue, headache, difficulty micturition, reduced GI peristalsis |
|
|
Term
| effects of Atropine: 10 mg |
|
Definition
| hallucination, delirium, coma |
|
|
Term
|
Definition
| Amitriptyline, Doxepin, Imipramine (alpha-r agonist/anticholinergic) |
|
|
Term
|
Definition
| Desipramine, Nortriptyline, Protriptyline |
|
|
Term
| Desipramine and Protriptyline |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Dramamine, Benadryl, Unisom Nighttime Sleep Aid, Dimetapp Allergy, Chlor-Trimeton |
|
|
Term
| Diazepam (valium), Flurazepam (dalmane) |
|
Definition
| highly lipid soluble, long half life, active metabolites-- clonazepam best alternative in this group |
|
|
Term
| Lorazepam (Ativan), temazepam (Restoril) |
|
Definition
| no active metabolites, intermediate half life |
|
|
Term
| Triazolam (Halcion), Oxazepam (Serax) |
|
Definition
| no active metabolites, short half life |
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