Term
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Definition
Prostaglandin E1 analog: replaces gut - protective PG removed by NSAIDs |
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Term
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Definition
forms a complex by binding with positivley charged proteins that protect the stomach lining against pepsin and HCL |
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Term
Name the cytoprotective agents |
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Definition
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Term
Brand name for misoprostol |
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Definition
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Term
What pregnancy category is misoprostol? |
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Definition
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Term
should misoprostol be used on women of child bearing age? |
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Definition
Do not use in women of childbearing age unless strict compliance with contraceptive measures |
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Term
starting dose for misoprostol |
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Definition
Can start with 100 mcg right after dinner (with food in stomach), attempt to increase as-directed. Use of psyllium (Metamucil) may help decrease diarrhea |
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Term
Major side effect of sucralfate? |
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Definition
major side effect is constipation; drink adequate fluids and use laxitives if directed. |
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Term
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Definition
Statement. Not a question. |
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Term
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Definition
Dopamine antagonist. At higher doses, blocks 5HT receptors in chemoreceptor zone, enhances response to acetylocholine causing enhanced motility and accelerated gastric emptying (peristatic speed) |
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Term
brand name for Metoclopramide |
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Definition
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Term
Dosing for metoclopramide |
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Definition
10 mg QID 30 min before meals and at bedtime |
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Term
Other concerns regarding metoclopramide |
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Definition
Serious ADRs due to DA - blockade
Extrapyramidal symptoms (EPS), including Parkinsonism (Parkinson disease - like symptoms) |
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Term
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Definition
Statment. Not a question. |
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Term
Should metoclopramide be used in those receiving meds for parkinson disease? |
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Definition
No. Do not use in patient receiving medication for Parkinson disease (counter - effect)
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Term
Should alcohol be avoided whilst on this drug? |
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Definition
Avoid consuming alcohol during treatment with this drug. Alcohol may increase drowsiness and dizziness. |
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