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genital herpes
ONU med micro r-anderson
12
Microbiology
Undergraduate 2
10/25/2011

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Cards

Term
causative agent
Definition
herpes simplex virus type II
HSVII
Term
etiology
Definition
dsDNA
polyhedral capsid, enveloped
large size
forms provirus in neurons
Term
reservoir
Definition
infected people
Term
transmission
Definition
direct intimate contact during sexual intercourse
oral:genital route (HSVI)
Term
signs/symptoms
Definition
3-7 days incubation
multiple painful vesicles form and break down into ulcers
vaginal/urethral discharge
regional adenopathy
ulcers heal over 2 weeks
Term
extra signs/symptoms of primary infection
Definition
headache, malaise, fever
Term
entry
Definition
direct contact
Term
attachment
Definition
attaches to epithelium of genitals
Term
avoid host defenses
Definition
intracellular pathogen, epithelial surface, forms provirus in dorsal root ganglia of sacral nerve
Term
damage
Definition
direct: lysis
inflammation
Term
diagnosis
Definition
clinical appearance
confirmed by DFA or Giemsa stain of scraping
Term
treatment
Definition
occasional outbreaks - topical acyclovir
reccurrent outbreaks - low doses acyclovir for 1-3 years
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