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Definition
| HATs attracted to gene by transcription factors, acetyl groups added to histone tails, core particle opened to RNA Pol, Histone Deacetylases reverse the process. |
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| Point of RNA polymerase binding and associated upstream elements. |
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| Elements Shared by Promoters |
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Definition
| TATA Box (25-30 bases upstream), CAAT Box (70 to 80 bases upstream), GC Box (about 110 bases upstream). |
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Definition
| Increase transcritional efficiency, can be located anywhere around or in regulated gene, can be inverted. |
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| True Activator Transcription Factors |
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Definition
| Proteins that bind to promoters and enhancers to facilitate efficient transcription. Positive control, DNA-binding domain, Trans-activating domain. |
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| Major Structural Motifs in Transciption Factors (3) |
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Definition
| Helix-turn-helix, Zinc finger, leucine zipper |
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Definition
| Transcription factors build onto promoters and enhancers, creates correct ocnditions for binding of RNA Polymerase holoenzymes. |
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Term
| Alternative mRNA Splicing |
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Definition
| One raw mRNA transcript may be spliced in two or omre ways yielding different proteins. |
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Term
| Preprotachykinin mRNA (3) |
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Definition
| Two neuropeptides in cows - P and K, Depends on splicing of K exon, Expressed in different tissues. |
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Term
| RNA-induced silencing complex |
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Definition
| Complex of siRNA's and proteins. Can degrade mRNA stopping translation. |
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Definition
| Small interfering RNA's that complex with other proteins to repress transcription. |
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