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Genetics Vocab chapter 2
Genetics: A conceptual approach
24
Biology
Undergraduate 2
09/03/2011

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Term
cohesin
Definition

Molecule that holds together the two sister chromatids of a chromosome together. The breakdown of cohesin at the centromeres enables the chromatids to separate in anaphase of mitosis and anaphase II of meiosis. 

 

Term
homologous chromosome pair
Definition
two chromosomes that are alike in structure and size and that carry genetic information for the same set of hereditary characteristics. One chromosome of the pair is inherited from the male parent and the other is inherited from the female parent.
Term
mitosis
Definition
Mitosis is a cellular process that replicates chromosomes and produces two identical nuclei in preparation for cell division. Generally, mitosis is immediately followed by the equal division of the cell nuclei and other cell contents into two daughter cells.
Term
meiosis
Definition
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent). To maintain this state, the egg and sperm that unite during fertilization must be haploid, meaning they each contain a single set of chromosomes. During meiosis, diploid cells undergo DNA replication, followed by two rounds of cell division, producing four haploid sex cells.
Term
chromatid
Definition
A chromatid is one of two identical halves of a replicated chromosome. During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.
Term
centromere
Definition
A centromere is a constricted region of a chromosome that separates it into a short arm (p) and a long arm (q). During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.
Term
telomere
Definition
A telomere is the end of a chromosome. Telomeres are made of repetitive sequences of non-coding DNA that protect the chromosome from damage. Each time a cell divides, the telomeres become shorter. Eventually, the telomeres become so short that the cell can no longer divide.
Term
origin of replication
Definition
site where DNA synthesis is initiated
Term
homologous recombination (crossing over)
Definition
Homologous recombination is a type of genetic recombination that occurs during meiosis (the formation of egg and sperm cells). Paired chromosomes from the male and female parent align so that similar DNA sequences from the paired chromosomes cross over each other. Crossing over results in a shuffling of genetic material and is an important cause of the genetic variation seen among offspring.
Term
cell cycle
Definition
A cell cycle is a series of events that takes place in a cell as it grows and divides. A cell spends most of its time in what is called interphase, and during this time it grows, replicates its chromosomes, and prepares for cell division. The cell then leaves interphase, undergoes mitosis, and completes its division. The resulting cells, known as daughter cells, each enter their own interphase and begin a new round of the cell cycle.
Term
chromatin
Definition
Chromatin is a substance within a chromosome consisting of DNA and protein. The DNA carries the cell's genetic instructions. The major proteins in chromatin are histones, which help package the DNA in a compact form that fits in the cell nucleus. Changes in chromatin structure are associated with DNA replication and gene expression.
Term
histone
Definition
A histone is a protein that provides structural support to a chromosome. In order for very long DNA molecules to fit into the cell nucleus, they wrap around complexes of histone proteins, giving the chromosome a more compact shape. Some variants of histones are associated with the regulation of gene expression.
Term
microsporocyte
Definition
Diploid reproductive cell in the stamen of a plant; undergoes meiosis to produce four haploid microspores.
Term
microspore
Definition
Haploid product of meiosis in plants.
Term
megasporocyte
Definition
In the ovary of a plant, a diploid reprodctuve cell that undergoes meiosis to produce haploid macrospores.
Term
megaspore
Definition
One of four products of meiosis in plants.
Term
gamete
Definition
Haploid reproductive cell, sperm and egg.
Term
ovum
Definition
Final product of oogenesis
Term
sperm
Definition
Male reproductive cell
Term
prophase
Definition
Stage of mitosis. In prophase, the chromoses contract and become visible, the cytoskeleton breaks down, and the mitotic spindle begins to form.
Term
metaphase
Definition
Stage of mitosis. In metaphase, chromosomes align in the center of the cell.
Term
anaphase
Definition
Stage of mitosis in which chromatids separate and move toward the spindle poles.
Term
telophase
Definition
Stage of mitosis. In telophase, the chromosomes arrive at the spindle poles, the nuclear membrane reforms, and the chromosomes relax and lengthen.
Term
cytokinesis
Definition
Process by which the cytoplasm of a cell divides.
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