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Genetics Test 3
genetics Klug ch 11-15
18
Biology
Undergraduate 3
03/28/2010

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Term
form of DNA not observed in viruses
Definition
Double-stranded branched DNA
Term
bacterial virus has a linear double-stranded DNA genome packaged in the virion capsid but converts to a circular double-stranded form upon infection
Definition
bacteriophage lambda
Term
DNA wound around itself in the direction opposite of the helix, underwound
Definition
negatively supercoiled DNA
Term
closed circular bacterial and viral DNA?
Definition
DNA is typically underwound and negatively supercoiled
Term
Topoisomerase type I
Definition
cleaves one strand of a DNA duplex
Term
Topoisomerase type II
Definition
cleaves both strands
Term
why are polytene chromosomes weird
Definition
replicated many times without concomitant cell division. More unusual is the fact the chromosomes are paired in a cell that is not undergoing meiosis and is not even a gamete.
Term
heterochromatin does NOT
Definition
replicate early in S phase
Term
Which type of DNA is not repetitive?
Definition
Telomerase DNA (euchromatin, very unique)
Term
Viral genomes and Eularyotic genomes BOTH have
Definition
the ability to pack large amounts of DNA into a small volume
Term
euchromatin is replicated
Definition
early
Term
first order of chromatin packing?
Definition
coling around the nucleosomes
Term
Which DNA polymerase is mainly responsible for genome replication in E. coli?
Definition
DNA polymerase III
Term
PO4 is not directly involved in what?
Definition
DNA synthesis
Term
okazaki fragments are formed where?
Definition
the lagging strand
Term
Which enzyme or enzymatic activity is not involved in resolution of the Okazaki fragments in E. coli?
Definition
RNA ligase
Term
the consequence of a mismatch in the heteroduplex that forms during general recombination?
Definition
gene conversion
Term
The discovery of Okazaki fragments suggested that DNA synthesis is
Definition
discontinuous
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