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Genetics Final...Forrester 311
Genetics Vocabulary
60
Science
Undergraduate 3
12/17/2009

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Term
lysogen 
Definition
A bacterial cell that harbors a phage genome integrated within the bacterial genome 
Term
heteroplasmy
Definition

there is a mixture of mutant and wild type organelles, such as mitochondria.

Term
episome 
Definition
A genetic element that can exist either free in the cytoplasm or integrated into the chromosome 
Term
allopolyploidy
Definition
Naturally occuring Xenopus laevis have 4 sets of chromosomes. They appear to be derived from two different species. If true, then Xenopus is an example of  
Term
 Aneuploidy  
Definition

is the situation where the chromosome number differs from normal by less than a full set.

Term
Gene therapy  
Definition
the use of recombinant DNA technology to correct a human genetic disorder.
Term
Roberstonian translocation  
Definition
is a special type of rearrangement in which the two long arms of two acrocentric chromosomes fuse. One such rearrangement causes a high frequency of Down Syndrome.
Term
 merodiploid
Definition
a bacterial cell having two copies of a gene
Term
reporter transgene
Definition
fusion of a gene or its promoter to a gene that produces an easily detected product, like gfp. 
Term
RNA mediated intereference (RNAi): 
Definition

Use of double stranded RNA to target an endogenous mRNA for degradation. 

Term
heterochromatin
Definition
Densely staining, compact and relatively transcriptionally inactive regions of chromosomes are referred to as
Term
primary culture
Definition
The culture of “normal”, untransformed somatic cells is called
Term
reversion
Definition
A change in DNA sequence that converts a mutation back to wild type sequence is called a(n)
Term
transition
Definition
mutation would be substitution of a G for an A
Term
Genetic anticipation
Definition
is the occurrence of a disorder at progressively younger ages in subsequent generations.
Term
telomeres
Definition
The specialized structures that protect the ends of chromosomes from becoming shortened as a consequence of replication are called
Term
locus
Definition
The site on the chromosome that a gene occupies is referred to as a(n)
Term
null mutation
Definition
Completely eliminates gene function
Term
epistasis
Definition
Phenotypic expression from one locus depends on the genotype at another.
Term
holocentric
Definition
Chromosome in which centromere forms along its entire length
Term
mitotic spindle
Definition
the structure that physically moves chromosomes during cell division.
Term
Pleiotropy
Definition
is when a mutation in a single gene affects many traits.
Term
homozygous
Definition
c. An individual in which all copies of a particular gene are identical is said to be
Term
Phenotype
Definition
refers to observable properties of an individual
Term
pseudoautosomal
Definition
region is the small region found on both the X and Y chromosomes.
Term
semi or incompletely dominant
Definition
When heterozygotes display a phenotype intermediate between that of individuals homozygous for either form of the gene, the trait is said to be
Term
Nondisjunction
Definition
was viewed by many as proof of the chromosome theory of inheritance.
Term
synapsis
Definition
Pairing of homologous chromosomes during meiosis
Term
allele
Definition
are different versions or forms of a gene.
Term
haploinsufficient
Definition
Where having one wild type copy of a gene is not enough to prevent a mutant phenotype.
Term
homeotic
Definition
genes specify the identity of Drosophila segments.
Term
Domains
Definition
are blocks of conserved structure and function that are found within a number of different proteins.
Term
gene pool
Definition
The complete set of genetic information within all of the individuals in a population
Term
autotetraploid
Definition
Naturally occurring Xenopus laevis have 4 sets of chromosomes. They appear to be derived from a single parent species. If true, then Xenopus laevis provides an example
Term
chiasmata
Definition
are the physical manifestation of crossing over, visible during portions of meiosis I.
Term
apoptosis
Definition
Damaged or defective cells can be induced to die by activating a process known as
Term
paralogs
Definition
Genes that arise by duplication within a species are
Term
morphogen
Definition
A protein that specifies different fates depending on its level is
Term
equivalence group
Definition
Several cells that have the same developmental potential (i.e. can adopt the same fate) constitute a(n)
Term
cyclins
Definition
are a class of proteins whose levels fluctuate as cells progress through the cell cycle.
Term
null mutation
Definition
A mutation that completely abolishes gene function is called
Term
lysogen
Definition
A bacterial cell that harbors a phage genome integrated within the bacterial genome is called a
Term
dosage compensation:
Definition
Normalization of gene expression from the X chromosome between males and females.
Term
telomerase
Definition
Enzyme that adds hexanucleotide repeats to the end of eukaryotic chromosomes.
Term
replicative transposition
Definition
Transposition that produces a new copy of the transposable element. Many of these move as an RNA intermediate.
Term
heteroplasmy
Definition
A mixture of both mutant and wild-type mitochondria within a
Term
gene pool
Definition
The complete set of genetic information within all of the individuals in a population is
Term
Proto-oncogene
Definition
is a normal cellular gene that can mutate to contribute to the development of cancer.
Term
alleles
Definition
Different versions of a gene are referred
Term
morphogen
Definition
A protein that specifies different fates depending on its
Term
merodiploid
Definition
A bacterial cell that is diploid for a portion of its genome is referred to
Term
homeosis
Definition
The replacement of one body part with another is
Term
Dosage compensation
Definition
normalizes the level of expression of X-linked genes between males and females.
Term
Linkage
Definition
is the tendency of genes located on the same chromosome to be inherited together.
Term
apoptosis
Definition
Damaged or defective cells can be induced to die by activating a process known as
Term
segment polarity
Definition
genes provide anterior-posterior information within each Drosophila segment.
Term
conservative transposition,
Definition
the element excises itself from the DNA and moves to a new location. The total number of transposable elements in the cell remains the same.
Term
equivalence group
Definition
A group of cells with equal developmental potential
Term
RNA interference
Definition
The process where introduction of double stranded RNA targets the corresponding endogenous RNA for degradation.
Term
synapsis
Definition
Paring of homologous chromosomes during meiosis.
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