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Genetics Exam 1
N/A
24
Biology
Undergraduate 2
09/19/2012

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Term
Gene
Definition
A gene is the molecular unit of heredity of a living organism
Term
Allele
Definition
ne of a number of alternative forms of the same gene or same genetic locus
Term
Relationship between genes, DNA, and chromosomes.
Definition
DNA is hereditary material, strands of DNA are called chromosomes, a gene is a small segment of DNA on a small piece of a chromosome
Term
Central Dogma of Molecular Biology
Definition
each gene in the DNA molecule carries the information needed to construct one protein, which, acting as an enzyme, controls one chemical reaction in the cell.
Term
Nucleotide structure
Definition
The nucleotide in DNA consists of a sugar (deoxyribose), one of four bases (cytosine (C), thymine (T), adenine (A), guanine (G)), and a phosphate. Cytosine and thymine are pyrimidine bases, while adenine and guanine are purine bases. The sugar and the base together are called a nucleoside.
Term
Describe the different kinds of bonds present in a DNA molecule
Definition
-Hydrogen bonds link bases of antiparallel strands.
-Phosphodiester bonds connect the sugar and phosphate groups of adjoining nucleotides
Term
DNA's three major functions as a heredity molecule
Definition
Contain complex information
Replicate faithfully
Encode the phenotype
Term
Chromatin
Definition
Complex of DNA and proteins that make up the contents of the nucleus of a cell. The primary functions of chromatin are 1) to package DNA into a smaller volume to fit in the cell, 2) to strengthen the DNA to allow mitosis, 3) to prevent DNA damage, and 4) to control gene expression and DNA replication. The primary protein components of chromatin are histones that compact the DNA. Chromatin is only found in eukaryotic cells
Term
Euchromatin
Definition
condensation and decondensation in cell cycle. Contains majority of chromosomal material
Term
Heterochromatin
Definition
highly condensed throughout the cell cycle. At centromeres and telomeres
Term
Prokaryotic chromosomes
Definition
nucleoid, held in place by proteins
Term
Eukaryotic chromosomes
Definition
changes regularly. Less packaged during interphase
Term
Outline the different levels of eukaryotic chromatin packaging from small scale to large scale.
Definition
o Nucleosome has DNA wrapped around an octamer of 8 histone proteins.
o Nucleosome + H1 histone = chromatosome.
o Looped fibers
Term
Unique sequence DNA
Definition
unique
encodes proteins
Term
Moderately repetitive DNA
Definition
may make up tRNA and rRNA
most has no known function
Term
Highly repetitive DNA
Definition
near centromeres and telomeres
no known function
Term
Miescher
Definition
discovered nucleic acid from pus
Term
Kossel
Definition
four nitrogenous bases
Term
Levene
Definition
repeating units called nucleotides that contained a base, a sugar, and a phosphate.
Term
Chargraff
Definition
different organisms have different compositions of bases
Term
Data Watson & Crick used to theorize the structure of DNA
Definition
X-ray diffraction
Term
Which nucleotide bonds are stronger
Definition
CG because they are held together by 3 H bonds

AT have 2
Term
Polycistronic mRNA
Definition
means that single mRNA can code for several genes. This kind of mRNA is found in like prokaryotes but not in eukaryotes.
Term
Shine-Dalgarno sequence.
Definition
o A ribosomal binding site in prokaryotic mRNA, generally located around 8 bases upstream of the start codon AUG.
o Helps recruit the ribosome to the mRNA to initiate protein synthesis by aligning it with the start codon.
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