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Genetics Chapter 4
Intro to Genetic Analysis 9th Edition
12
Biology
Undergraduate 2
02/23/2009

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Term
Chromosome Map
Definition
A representation of all chromosomes in the genome as lines, marked with the positions of genes. Also shows distances between the loci based on some kind of scale.
Term
Recombination Map
Definition
A chromosome map in which the positions of loci shown are based on recombinant frequencies.
Term
Linked
Definition
The situation in which two genes are on the same chromosome as deduced by recombinant frequencies less than 50 percent.
Term
Crossing Over
Definition
The exchange of corresponding chromosomes parts between homologs by breakage and reunion.
Term
Cis Conformation
Definition
In a heterozygote having two mutant sites within a gene or gene cluster, the arrangement A1A2/a1a2.
Term
Trans Conformation
Definition
In a heterozygote with two mutant sites within a gene or gene cluster, the arrangement a1+/+a2.
Term
Linkage Map
Definition
A chromosome map; an abstract map of chromosomal loci that is based on recombinant frequencies.
Term
Genetic Map Unit (m.u.)
Definition
A distance on the chromosome map corresponding to 1 percent recombinant frequency.
Term
Recombinant Frequency (RF)
Definition
The proportion (percentage) of recombinant cells or individuals.
Term
Three-point Testcross
Definition
A testcross in which one parent has three heterozygous gene pairs.
Term
Interference
Definition
A measure of the independence of crossovers from each other, calculated by subtracting the coefficient of coincidence (c.o.c) from 1. 1- c.o.c.
Term
Coefficient of Coincidence (c.o.c.)
Definition
The ratio of the observed number of double recombinants to the expected number. O/E.
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