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Genetics Ch 25
Bio 310-01
28
Biology
Undergraduate 2
12/09/2012

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Term
Population genetics
Definition
study of genes and genotypes in a population
Term
population
Definition
a group of individuals of the same species that occupy the same region and can interbreed with one another
Term
gene pool
Definition
all alleles for every gene within a population
Term
polymorphic
Definition
multiple alleles exist for a specific gene
Term
what is the point of determining allele and genotypic frequencies?
Definition
to predict if it is experiencing evolutionary change
Term
Hardy-Weinberg equilibrium
Definition
allele and genotype frequencies of a population are not changing over many generations
Term
Hardy-Weinberg equation
Definition

p+ 2pq + q= 1

 

p= allele frequency of allele #1

q= allele frequency of allele #2

 

Term
Darwinian fitness
Definition
likelihood that a genotype will contribute to the gene pool of the next generation as compared to other genotypes
Term
Microevolution
Definition
changes in a population's gene pool from one generation to the next
Term
4 types of Natural selection
Definition

directional

stabilizing

diversifying(disruptive)

balancing

Term
directional selection
Definition

An extreme phenotype confers higher fitness

Intermediate genotypes may eventually be eliminated

Term
Stabilizing selection
Definition

favors organisms with intermediate phenotype

extreme genotypes are eventually eliminated

Term
diversifying (disruptive) selection
Definition

heterogeneous environments

some organisms survive better in diff parts of the environment

 

Term
balancing selection
Definition

maintains genetic diversity

genes remain polymorphic

heterozygote advantage

Term
heterozygote advantage
Definition

when the heterozygote has advantage over either homozygote

Ex. carrier/infected with sickle cell anemia means they are immune to malaria.

Term
genetic drift
Definition

random change in a population's allele frequencies that are unrelated to fitness and genotypes

has greater impact  on smaller populations

favors loss of fixation of a particular allele

Term
fixation
Definition

means it has 100% frequency on that population

ex. we would all have blue eyes

Term
bottleneck effect
Definition

population is drastically reduced in size

reduction in genetic diversity

due to natural disaster that wipes out an area

Term
founder effect
Definition

small group separates from the population

the new population will have less genetic variation

usually separated b/c of natural disaster

usually unintentional and unwilling

Term
migration
Definition
movement of organisms and genes from one population to another
Term
gene flow
Definition
movement of gene from 1 population to another
Term
nonrandom (assortative) mating
Definition
mates are chosen based on their phenotype
Term
Inbreeding
Definition
to mate with a genetically related organism
Term
outbreeding
Definition
genetically different organisms are mating
Term
Inbreeding depression
Definition
occurs b/c you have a smaller gene pool
Term
random mutation
Definition

affects our DNA regardless of fitness

physically and genetically might occur

Term
Exon shuffling
Definition

get a new allele to appear

subunits of a protein rearranged to get a different combination- nothing is lost, you still get a protein, just a very different protein

Term
horizontal gene transfer
Definition
occurs b/w organisms in the same generation
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