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organs specialized to detect a certain stimulus |
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convert the stimulus into an electrical signal |
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the type of stimulus to which a sensory organ is particularly adapted |
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Doctrine of Specific Nerve Energies |
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1. Receptors and neural channels for different senses are independent
2. Each sense uses a different "nerve energy" |
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says that the brain recognizes distinct senses because action potentials travel along separate nerve tracts |
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Where sensory processing begins |
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the conversion of electrical energy from a stimulus into a change in membrane potential in a receptor cell |
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local changes in membrane potential |
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Stimulates pain and temperature |
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1. Mechanical stimulation deform the corpuscle 2. Deformation of corpuscle stretches the tip of axon 3. Opening of Na+ channels |
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3 steps to the Pacinian Corpuscle Function |
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patterns of action potentials in a sensory system that reflect a stimulus |
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by changing the frequency of its action potentials
(can't increase intensity of action potentials) |
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How a single neuron can convey stimulus intensity |
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as the stimulus strengthens, more neurons are recruited because there are neurons that have different threshold levels |
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How multiple neurons can convey stimulus intensity |
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takes place when different cells have different thresholds for firing over a range of stimulus intensities |
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detects body sensations, including touch and pain |
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from the position of the activated receptors |
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How stimulus location is determined |
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the progressive loss of response to a maintained stimulus |
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show slow or no decline in action potential frequency
- do not respond to adaptation |
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display adaptation and decrease frequency of action potentials |
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1, Accessory structures Ex: eyelids 2. Central Modulation of Sensory Modulation |
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2 ways to control information to accentuate important changes in stimuli |
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Central Modulation of Sensory Modulation |
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Definition
higher brain centers suppress some sensory inputs and amplify others |
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where most sensory pathways pass through on their way to the cerebral cortex |
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the space in which a stimulus will alter a neuron's firing rate
- differ in size, shape, and response to types of stimulation |
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exists for each modality
- receives touch information from the opposite side of the body |
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Secondary Sensory Cortex/Non-primary sensory cortex |
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receives its main input from the primary cortical area for that modality
- where memories begin to be stored
- maps both sides of the body |
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may be the generalized state of awareness of inputs
- may also allow selection of some inputs over others |
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allow for intersensory interactions |
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a condition in which a stimulus in one modality creates a sensation in another
Ex: a person may perceive colors when looking at letters, or taste when hear a tone |
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1. Epidermis 2. Dermis 3. Hypodermis |
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outermost layer of skin; thinnest |
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middle layer; contains nerve fiber |
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anchors muscles and helps shape body |
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1. Pacinian Corpuscle 2. Meissner's Corpuscle 3. Merkel's Discs 4. Ruffini's Endings 5. Hair Follicle Receptor |
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5 tactile receptors perceive touch |
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delivers touch information to the brain |
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where receptor axons synapse in the spinal cord |
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Density of body innervation |
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What brain regions reflect |
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How receptive fields can be changed |
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an unpleasant experience associated with tissue damage |
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Congenital Insensitivity to Pain |
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an inherited syndrome where patients cannot sense pain |
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1. Withdraw from its source 2. Engage in recuperative actions 3. Signal others |
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What does pain help us do? |
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1. Sensory-discriminative 2. Motivational-affective 3. Cognitive-evaluative |
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3 aspects of pain described in the McGill Pain Questionnaire |
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Sensory-Discriminative Quality |
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Motivational-Affective Quality |
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peripheral receptors that respond to painful stimuli |
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have specialized receptor proteins that respond to temperature changes, chemicals, and pain
- located in the dermis |
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the "hot" in chili peppers |
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Transient Receptor Potential Vanilloid Type 1 (TRPV1) |
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the receptor that binds capsaicin
- normally detects painful heat
- located on C fibers |
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- detects higher temperatures
- does NOT respond to capsaicin
- is found on A-delta fibers |
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large myelinated axons that register pain quickly |
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thin unmyelinated axons that conduct slowly, producing lasting pain |
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Cool-menthol Receptor 1 (CMR1) |
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Definition
responds to menthol and to cool temperatures
- located on C fibers |
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Anterolateral/Spinothalamic System |
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Definition
transmits sensations of pain and temperature |
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where free nerve endings synapse onto spinal neurons |
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- used to excite spinal cells in the dorsal horn |
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a peptide that is released by peripheral fibers
- post-synaptic neurons take it up and remodel dendrites, which may affect pain perception |
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Neuropathic Pain/Phantom Limb Pain |
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may be due to inappropriate signaling of pain by neurons |
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when dorsal horn neurons become hyperexcitable |
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Definition
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where pain information is integrated
- different sub-regions are activated if a person is experiencing pain or is empathizing with another |
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the loss of pain sensation |
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endogenous opiate-like peptides in the brain |
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1. Endorphins 2. Enkephalins 3. Dynorphins |
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3 classes of endogenous opioids |
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respond to opiates or opioids |
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Transcutaneous Electrical Nerve Stimulation (TENS) |
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delivers electrical pulses to the skin
- relieves pain by stimulating the nerves around the source of pain |
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an opioid antagonist that can block the analgesic effect of TENS |
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an inert substance that can sometimes relieve pain |
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relieves pain by inducing endorphin release |
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