What condition is described as follows:

Strong association with diabetes mellitus (but affects less than 1%).

Lesions common on the leg

Enlarging plaques with inflammatory border

Inflamed fat and atrophy of epidermis

Yellow centre with superficial vessels

HbA1C does not induce regression

Treat with top. steroid, tretinoin, PUVA

Acne vulgaris

Name two psychological grading systems

APSEA: Assessment of the Psychological and Social Effects of Acne

CADI: Cardiff Acne Disability Index

Acne vulgaris

Name the beneficial actions of Adapalene + Retinoids

- Anti-comedonal

- Anti-inflammatory

- Sebum reduction

Acne - True or false

Serum reduction is effected by topical benzoyl peroxide

Acne vulgaris.

What is the rate of p.acnes resistance to Erythromycin?

Acne vulgaris.

What is the rate of p.acnes resistance to Tetracycline?

Acne vulgaris.

List the adverse effects associated with minocycline use

Pigmentary skin changes

Lupus-like syndrome

Benign intracranial hypertension

Isotretinoin.

List the adverse effects

Mucocutaneous:

Cheilitis

Nasal crusting

Conjunctivitis

Facial and general dermatitis

Skin fragility

Psychiatric:

Mood swings

Depression

Other:

Highly teratogenic - Informed consent, Double contraception cover, Pregnancy tests 5wks before tx then monthly, Start day 3 of cycle

Dyslipidaemia: Hypertriglyceridaemia

Dermatitis Herpetiformis.

Which of these two treatments are usually very effective at clearing the severely pruritic rash in a matter of days?

Oral steroids?

Dapsone?

Dapsone.

This is also a treatment of choice in Leprosy, TB and Pneumocystis infection

Tuberous sclerosis. Which of the following is false?

i – Autosomal dominant inheritance

ii – Angiofibromas and periungual fibromas may be found

iii – A positively fluorescing Shagreen patch (soft skin coloured lumbosacral patch) may be present

iv – Ash leaf macules with no fluorescence under Wood’s light can be seen

v – Fibromatous forehead nodules may be present

vi – Extracutaneous associations include mental retardation, cardiac and renal tumours

iv is false. Ash leaf macules in Tuberous sclerosis do fluoresce under Wood’s light.

Allergic contact dermatitis. True or false. Previous allergen exposure is needed to induce allergy.

Sezary syndrome. Which of the following is not necessarily a feature?

Erythroderma

Circulating malignant T-cells

Lymphadenopathy

Severe pyrexia

Pyrexia is not a feature in the definition of Sezary syndrome.

Dermatomyositis. This an Inflammatory condition of striated muscle & skin. It is linked with internal malignancy. The muscle signs are proximal muscle weakness (Can’t stand up, can’t brush hair) & later myalgia. What are the 3 skin signs in this condition?

1.Heliotrope rash of eyes

2.Gottron’s papules (purple-red papules around knuckles)

3. Nail fold telangiectasiae.

X-linked ichthyosis. This is due to steroid sulphatase deficiency, the first sign being a difficult delivery of a male baby. True or false, the flexures are usually involved.

What disease is associated with “Axillary freckling”

Fitzpatrick’s sign is found with dermatofibromas. True or false?

 True. This is the dimple sign.

Erythema Multiforme.

What proportion of patients have oral lesions?