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General Bio Chapter 7
Chapter 7
43
Biology
Undergraduate 1
09/24/2010

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Term
Energy
Definition
capacity to do work
Term
Kinetic Energy
Definition
the energy of montion, is used and work is performed
Term
Potential energy
Definition
the capacity to do work as a result of position or state
Term
Chemical energy
Definition
potential energy stored in chemical bonds
Term
Thermodynamics
Definition
the study of energy and its transformations; governs all activities of the universe
Term
First Law of Thermodynamics
Definition
energy cannot be created or destroyed, although it can be transferred or converted from one form to another
Term
Closed System
Definition
does not exchange energy with its surroundings
Term
Open System
Definition
system that can exchange energy with its surroundings (e.g. biological systems)
Term
Second law of thermodynamics
Definition
when energy is converted from one form to another, some usable energy is converted into heat that disperses into the surroundings
Term
Heat
Definition
the kinetic energy of randomly moving particles
Term
Entropy (S)
Definition
measure of randomness (of particles, etc.)
Term
Metabolism
Definition
the sum of all the chemical activities taking place in an organism
Term
Anabolism
Definition
includes various pathways in which complex molecules are synthesized from simpler substances
Term
Catabolism
Definition
includes the pathways in which larger molecules are broken down into smaller ones
Term
Enthalpy (H)
Definition
total potential energy of the system
Term
Free Energy (G)
Definition
the amount of energy available to do work under the conditions of a biochemical reaction
Term
Exergonic Reaction
Definition
releases energy and is said to be a spontaneous reaction, from higher to lower free energy
Term
Endergonic Reaction
Definition
reaction in which there is a gain of free energy
Term
Concentration Gradient
Definition
provides energy for diffusion?
Term
Dynamic Equilibrium
Definition
when rate of the reverse reaction equals the rate of the forward reaction
Term
Coupled Reactions
Definition
when the thermodynamically favorable exergonic reaction provides the energy required to drive the thermodynamically unfavorable endergonic reaction
Term
ADP
Definition
remaining molecule when terminal phosphate is removed from ATP
Term
Phosophorylation Reaction
Definition
when a phosphate group is transferred to some other compound
Term
NAD+
Definition
one of most common accepter molecules
Term
NADP+
Definition
hydrogen acceptor that is chemically similar to NAD+ but has an extra phosphate group
Term
FAD
Definition
nucleotide that accepts hydrogen atoms and their electrons (reduced form is FADH2)
Term
Cytochromes
Definition
proteins that contain iron; the iron component accepts electrons to some other compound
Term
Activation Energy
Definition
the energy required to break the existing bonds and begin the reaction
Term
Substrate
Definition
substance on which enzyme acts
Term
Active Sites
Definition
Regions to which the substrate binds on an enzyme
Term
Induced Fit
Definition
change caused by binding of substrate to the enzyme molecule
Term
Cofactor
Definition
most enzymes require these + apoenzyme component for catalytic activity
Term
Coenzyme A
Definition
coenzyme involved in the transfer groups derived from organic acids
Term
Metabolic Pathway
Definition
assembly line of enzyme reactions depedent on one another
Term
Feedback Inhibition
Definition
type of enzyme regulation in which the formation of a productinhibits an earlier reaction in the sequence
Term
Allosteric Site
Definition
receptor site on some enzymes that is not in the same place as the active site
Term
Allosteric Regulators
Definition
substances that affect enzyme activity by binding to allosteric sites
Term
Reversibile Inhibition
Definition
when an inhibitor forms weak chemical bonds with the enzyme
Term
Competitive Inhibition
Definition
the inhibitor competes with the normal substrate for binding to the active site of the enzyme
Term
Noncompetitive Inhibition
Definition
the inhibitor binds with the enzyme at a site other than the active sit
Term
Irreversible Inhibition
Definition
an inhibitor permanently inactivates or destroys an enzyme when the inhibitor combines with one of the enzyme's functional groups, either at the active site or elsewhere
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