Shared Flashcard Set

Details

General Anesthetics
Test 2
15
Pharmacology
Professional
02/21/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Barbiturates
Definition
-Rapids onset (redistribution)
-Dont use for maintenance because terminal half-lives get longer with continued infusion (redistributes to tissues)
-Poor muscle relaxation and analgesia
Term
Thiopental
Definition
Barbiturate
Contra: Porphyria
Term
Thiamylal
Definition
Barbiturate
Term
Methohexital
Definition
Barbiturate
-Can get paradoxical muscle tremors/hiccups
-Has very rapid clearance
Term
Propofol
Definition
-Rapid clearance (rapid recovery) when compared to barbiturates
-Can be used for maintenance
Toxicities:
Decreased cerebral blood flow and metab, decreased BP, Pain on injection (not used w/ peds)
Term
Etomidate
Definition
-Cardiostable (good if risk of hypotension)
*Fentanyl prolongs elimination t1/2
Toxicities: Nausea and vomiting, suppression of adrenocortical stress response
Term
Ketamine
Definition
Glutamine receptor blocker (for short procedures)
-Useful if risk for hypoTN or Bronchospasm (asthma) because ^ BP and bronchodilates
*Can get emergence delirium
Intxns: Potentiates Nondepolarizing muscle relaxants
Ketamine+Theophylline=can cause seizure
Term
Minimum Alveolar Concentration
Definition
Concentration of gas in the alveolar compartment that results in a lack of response to a noxious stimuli in 50% of pts
Term
Halothane
Definition
-Induction of anasthesia slow
-MAC=.75% very potent!
Term
Enflurane
Definition
-Induction slow, largely used for maintenance
Sfx: Increased seizure activity
Term
Isoflurane
Definition
-Faster induction (but pungent odor so not often used)...good maintenance
-Potential for "Coronary Steal"
Term
Methoxyflurane
Definition
-Detrimental effect on kidneys (makes F- ions)
-slow onset and offset
Term
Nitrous Oxide (N20)
Definition
-Rapid induction and emergence (used as an adjunct)
-Cannot be used about 80% (causes Hypox)
Sfx: accumulates in gas filled spaces (bowel, pneumothorax, inner ear), give 100% after to avoid diffusional hypoxia, Contraindicated in **Pulmonary HTN (^ vascular resistance)
Term
Desflurane
Definition
-Rapid onset, and rapid emergence (good for outpatient surgeries) don't want to use for induction because of coughing, salivating, and bronchospasm in awake pts.
-Cardiac output not effected
Term
Sevoflurane
Definition
-Rapid onset, rapid recovery, used for induction
-Not irritating to airway
-Need to use as "Fresh Gas Flow" (potential for nephrotoxicity)
Supporting users have an ad free experience!