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make proteins, transciption and translation; |
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general way of thinking about flow of genetic info. |
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nucleic acid composed of nucleotides |
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Have three parts: sugar (ribose) phosphate nitrogen base The nitrogen base has two parts: purines: adenine and guanine pyrimidines: cytosine and uracil (only in RNA) |
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sequences of amino acids that correspond to genes; a proteins primary structure; |
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the only class of RNA that carries the protein-building codes. transcribed genes that specify proteins; |
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Ribosomal RNA and transfer RNA |
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adds ribonucleotides one at a time to the end of a growing strand of RNA. |
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Start signal, a base sequence in DNA to which RNA polymerases bind and prepare for transcription. |
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the first step in protein synthesis; a sequence of ncleotide bases is exposed in an unwound region of a DNA strand; |
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protein coding base sequences that are interrupted by nncoding sequences (introns); (all introns are snipped off before the transcript reaches the cytoplasm) |
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bse triplets in mRNA strands; |
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te set of sixty-four different codons; |
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a ribonucleotide base triplet that can base-pair with a complementary codon in an mRNA transcript, found in tRNA strands. |
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happens when tRNA and mRNA strands bind together; the freedom in codon-anticodon pairing at a base; |
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describe the interactions of tRNA and mRNA |
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intereactions between tRNA and mRNA take place at ribosomes. Only mRNA carries DNA's protein-building instructions from the nucleus into the cytoplasm; tRNA delivers amino acids to ribosomes. Their anticodons base-pair with codons in the order specified by mRNA. |
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What are the three stages of translation? |
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initiation, elongation, and termination |
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a polypeptide chain is synthesized while the mRNA passes between the two ribosomal subunits; i.e. athread being moved through the eye of a needle; RNA polymerse adds free complementary nucleotides to DNA strand; |
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RNA polymerse (tRNA) binds to DNA at promoter region; DNA polymerse unravel DNA dbl helix; |
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RNA polymer reaches stop sequence and stops transcription; |
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process of RNA makind protein; occurs in the cytoplasm methionine is the 1st amino acid in protein process in humans (20 total); |
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mismatched nitrogen base pair; |
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fall into to categories: insertion mutation - addition of nitrogen base deletion mutation- removal of a nitrogen base |
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jump around in the genome; segements of DNA (or sopies) that move spontaneously to a new location in a chromosome or even to a different chromosome. |
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form of radiation with enough energy to eject electrons from atoms; may cause mutations in DNA if exposed in large doses; |
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excites electrons to a higher energy level; |
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What are the most common types of gene mutations? |
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base-pair substitutions, insertions and deletions; |
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