Term
In mammals, dosage compensation results from a type of |
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Definition
epigenetic regulation, in which all of the genes on one X chromosome are transcriptionally silenced |
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Term
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Definition
above or in addition to DNA sequence |
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Term
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Definition
heritable changes in gene expression that are not due to changes in the DNA sequence itself |
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Term
The XIST gene product is a type of |
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Definition
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Term
XIST RNA binds and coats to the |
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Definition
X chromosome it is transcribed from, and no other location in the genome |
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Term
TSIX is proposed to prevent XIST RNA from |
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Definition
causing inactivation of the other active X chromosome |
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Term
X-inactivation occurs in the |
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Definition
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Term
The choice of chromosomes is random, but once an X chromosome is inactivated, |
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Definition
that designation is clonally inherited in all descendent cells |
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Term
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Definition
epigenetic silencing of specific chromosomal loci |
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Term
Inprint is transmitted from |
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Definition
one parent only (maternal vs paternal |
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Term
The net result in inprinting is |
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Definition
one of the two copies of target gene is silenced |
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Term
The imprint is erased in the what and reestablished in what? |
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Definition
Germline and gamete or zygote |
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Term
Usually paternally expressed genes does what to fetal growth and maternally expressed ones does what to fetal growth? |
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