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Gastrointestinal
Physiology
68
Physiology
Graduate
01/17/2014

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Term
peyer's patches
Definition
unencapsulated lymphoid tisue in lamina propria and submucosa of small intestine, contain M cells
Term
cells in peyer's patches
Definition
M cells
B cells -> IgA
Term
gastrin surce cells
Definition
G cells
Term
increase H+
Definition
gastrin
Term
increases growth of gastric mucosa
Definition
gastrin
Term
increased by AA
Definition
gastrin, CCK, GIP
Term
decreased by low pH
Definition
gastrin
Term
activated by phenylalanine, tryptophan and Ca
Definition
gastrin
Term
receptors that inhibit H+ secretion
Definition
prostaglandin, somatostatin
Term
receptors that increase H+ secretion
Definition
Ach, gastrin, histamine
Term
I cells
Definition
CCK
Term
increase pancreatic secretion
Definition
CCK, secretin
Term
GB contraction
Definition
CCK
Term
decrease gastric emptying
Definition
CCK
Term
increased by FA
Definition
CCK, GIP
Term
s cells
Definition
secretin
Term
decreases acid secretion
Definition
secretin, somatostatin, GIP
Term
activated by acid
Definition
secretin, somatostatin
Term
decreased by vagal stimulation
Definition
somatostatin
Term
D cells
Definition
somatostatin
Term
decreases pancreatic secretion
Definition
somatostatin
Term
decreases GB contraction
Definition
somatostatin
Term
decreases insulin and glucagon
Definition
somatostatin
Term
K cells
Definition
GIP
Term
increases insulin release
Definition
GIP
Term
increased by oral glucose
Definition
GIP
Term
parasympathetic ganglia releases ___
Definition
VIP
Term
increases water and electrolyte secretion
Definition
VIP
Term
increases relaxation of smooth mm and sphincters
Definition
VIP, NO
Term
decreased by adrenergic
Definition
VIP
Term
made in small intestine, causes MMC
Definition
motilin
Term
increases in fasting state
Definition
motilin
Term
made in parietal cells
Definition
IF and gastric acid
Term
helps B12 absorption
Definition
IF
Term
increased by histamine, ash, gastrin
Definition
gastric acid
Term
decreased by somatostatin, GIP, PG and secretin
Definition
gastric acid
Term
made in chief cells
Definition
pepsin
Term
protein digestion
Definition
pepsin
Term
increased by vagal stimulation
Definition
VIP, pepsin
Term
made in mucosal cells and brunner's glands
Definition
HCO3
Term
activated by secretin
Definition
HCO3
Term
digests starch
Definition
amylase
Term
neutralizes acids
Definition
HCO3
Term
lubricate food
Definition
mucins
Term
is saliva hyper or hypotonic?
Definition
hypotonic but more isotonic with higher flow rates
Term
hypertrophy in peptic ulcer dx
Definition
brunner's glands
Term
alpha-amylase
Definition
starch digestion, in active form from pancreas
Term
fat digestion pancreatic enzymes
Definition
lipase, PLA colipase
Term
protein digestion pancreatic enzymes
Definition
trypsin, chymotrypsin, elastase, carboxypeptidases
Term
converted by enterokinase/enteropeptidase
Definition
trypsinogen -> trypsin
Term
activates other proenzymes and more trypsinogen
Definition
trypsin
Term
starge digestion, yiel disaccharides
Definition
salivary amylase
Term
hydrolyzes starch to oligosaccharides and disaccharides
Definition
pancreatic amylase
Term
rate limiting step in carb digestion
Definition
oligosaccharide hydrolases
Term
produce monosaccharides
Definition
hdrolases on brush border
Term
fructose is taken up by
Definition
facilitated diffusion by GLUT5
Term
carbs transported to blood by
Definition
GLUT2
Term
location of iron absorption
Definition
duodenum
Term
location of folate absorption
Definition
jejunum
Term
location of B12 absorption
Definition
ileum
Term
location of B12 absorption
Definition
ileum
Term
iron absorption location
Definition
duodenum
Term
folate absorption location
Definition
jejunum
Term
B12 absorption location
Definition
ileum
Term
functions of bile
Definition
digestion and absorption of lipids and fat-soluble vitamins, cholesterol excretion and antimicrobial activity
Term
bile is composed of:
Definition
bile salts, phospholipids, cholesterol, bilirbin water and ions
Term
direct vs indirect bilirubin
Definition
direct = conjugated, water soluble
indirect = unconjugated, water insoluble
Term
bilirubin cycle
Definition
heme -> UC-bili -> albumin-UC-bili in blood -> liver -> C-bili -> gut bacteria -> urobilinogen -> 80% excreted and 20% reabsorbed
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