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Gastrointestinal Physiologyy
VT BMES 5004
50
Physiology
Graduate
12/11/2008

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Term
Macronutrition
Definition
Things eaten most days > 1 gm/day - sugars/starches, proteins, fats
Term
Micronutrition
Definition
Things eaten in amounts < 1 m/day - vitamins, minerals, trace elements
Term
Parotid
Definition
Largest of the salivary gland.
Term
Sublingual
Definition
Smaller salivary gland.
Term
Submandibular
Definition
Smaller salivary gland.
Term
Greater Omentum
Definition
Curtain of material hanging off the bottom of the stomach containing fat stores.
Term
Lesser Omentum
Definition
Curtain of material that hangs off the top of stomach hung by ligaments attached to the liver.
Term
Mesantary
Definition
Sheet of connective tissue that suspends the small intestine. Has lots of vessels to absorb nutrients. Large intestine also has a mesantary
Term
Hepatic artery
Definition
Bypasses the spleen and mesentary leading directly to the liver.
Term
Portal vein
Definition
Collects blood from the spleen and mesentary, delivering it to the liver.
Term
Villi
Definition
Folds of the small intestine with extensive circulation and lymphatics.
Term
Pyloric sphincter
Definition
Controls release of chyme from the stomach into the duodenum.
Term
Ileocecal sphincter
Definition
Regulates chyme release from the small intestine to the large intestine.
Term
Mucus
Definition
Secretion that acts as a lubricant and wall protectant.
Term
Hydrochloric Acid
Definition
Released by the stomach to aid in food breakdown.
Term
Pancreatic Enzymes
Definition
Basic substance released by the pancreas - neutralies hydrochloric acid in the duodenum.
Term
Bile
Definition
Secretion released by the liver. Breaks down lipids into emulsified fats.
Term
Oxyntic (parietal) cells
Definition
Create hydrochloric acid in the stomach and secrete it.
Term
Secretin
Definition
Released from the wall of the duodenum due to acid from the stomach. Stimulates bile production and causes secretion of pancreatic fluid and bicarbonate.
Term
Cholecystokinin
Definition
Released due to fats and amino acids.. Causes the gall bladder to contract releasing bile, and opens the sphincter of Oddi allowing the bile to flow into the duodenum.
Term
Sphincter of Oddi
Definition
Regulates release of bile from gall bladder into the duodenum.
Term
Carbohydrates
Definition
Starches and sugars. Easily dissolved in water and increased temperature leads to increased solubility. Made up of monosaccharides. Digest to glucose.
Term
Proteins
Definition
Somewhat dissolved in water. Increased temperature leads to decreased solubility. Hydrolyzed by hydrochloric acid. Broken down to peptides, digest to amino acids.
Term
Monosaccharide
Definition
Basic building block of carbohydrates. Three main types - glucose, galactose and fructose.
Term
Disaccharides
Definition
Formed by junctions of monosaccharides. Three types - sucrose (glucose-fructose), maltose (glucose-glucose) and lactose (glucose-galactose)
Term
Sucrase
Definition
Enzyme that breaks down Sucrose.
Term
Maltase
Definition
Enzyme that breaks down Maltose.
Term
Lactase
Definition
Enzyme that breaks down lactose.
Term
Monosaccharide chains
Definition
Complex sccharides that link large amonts of glucose together to form starches.
Term
Amino Acid
Definition
Basic building block of proteins. 22 different types.
Term
Pepsin
Definition
Enzyme that speeds up protein hydrolysis.
Term
Trypsin
Definition
Enzyme that breaks peptides down to amino acids.
Term
Cathepsin
Definition
Enzyme that breaks peptides down to amino acids.
Term
Fats
Definition
Composed of monoglycerides, fatty acids, and glycerol. Comes in the form of triglycerides.
Term
Pancreatic lipase
Definition
Breaks emulsified fat into fatty acids, monoglycerides and glcerol.
Term
Cholesterol
Definition
Form of fat. Two types: exogenous (absorbed in the gut) and endogenous (manufactured in liver and cells). Mainly used to manufacture liver and bile salts, hormones, steroids, and myelin sheath around nerves.
Term
Glycogen
Definition
Stored form of glucose. Formed from glucose in the presence of insulin, broken down in the presence of glucagon.
Term
Insulin
Definition
Released by beta cells in the pancreas. Prompts glucose uptake by cells, and subsequent storage.
Term
Hepatic Cells
Definition
Liver cells that create bile.
Term
Triglycerides
Definition
Primary storage form of fat.
Term
Chylomicrons
Definition
Form of fat storage that lasts about 10-15 minutes.
Term
Adipsin
Definition
Hormone that decreases appetite and increases metabolism.
Term
Achlorhydria
Definition
Failure to secrete Hydrochloric acid
Term
Gastritis
Definition
Inflammation of the Gastric mucosa
Term
Pernicious anemia
Definition
Intrinsic factor secreted by parietal cells that decreases B12 absorption.
Term
Peptic Ulcer
Definition
Develops from mucus barrier breakdown from bacterial infection, or non-bacterial causes.
Term
Pancreatitis
Definition
Caused by alcohol consumption and gallstone blockage of pancreatic duct.
Term
Gallstones
Definition
Caused by precipitants in liver bile. Gall bladder must be removed, and patient must avoid fats.
Term
Diarrhea
Definition
Blockage of water absorption usually caused by bacteria or virus.
Term
Appendicitis
Definition
Acute infection of the appendix. Needs to be removed before rupture.
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