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Gastrointestinal Disorders
Gastrointestinal Disorders
67
Nursing
Undergraduate 2
09/22/2012

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Term
Underweight
Definition
< 18.5
Term
Normal Weight
Definition
18.5-24.9
Term
Overweight
Definition
25.0-29.9
Term
Obese I
Definition
30.0-34.9
Term
Obese II
Definition
35.0-39.9
Term
Obese III
Definition
>40.0
Term
Obesity in children
Definition
Childhood obesity rising rapidly in all age groups causes Type II Diabeties
Term
Marasmus
Definition
protein and calorie deficiency
Term
Kwashiorkor
Definition
protein deficiency (enough calories)
Term
Malnutrition and Starvation
Definition
Skin breaks down, Hair, enlarged liver, edema (swelling)
Term
Malnutrition and Starvation Effects
Definition
-loss of muscle mass
-impaired wound healing**
-impaired immunologic function-->no proteins to make antibodies (glycoproteins)
-decrease appetite
-loss of calcium and phosphate from bone
-anovulation (not ovulating) & amenorrhea (no menstruating)
-decreased testicular function
Term
Anorexia nervosa
Definition
underweight (BMI <18.5)
Term
Bulimia nervosa
Definition
binge eating
inappropriate compensatory behaviors (vomit or laxatives of get out of body)
Term
Nausea
Definition
-stimulation of the medullary vomiting center
-distention of the duodenum
-may be accompanied by pallor, sweating, tachycardia, and water salvation
Term
Vomiting (Emesis)
Definition
-Triggered by vomiting center in medulla
-input from GI tact, cerebral cortex, vestibular apparatus (motion sickness, balance in ears (semicircular canal))
-Hypoxia is a strong trigger
-may involve the chemoreceptor trigger zone in the fourth ventricle
-ADAPTIVE MECHANISM
Term
Dysphagia
Definition
difficult swallowing with a sensation of chocking or food sticking in throat, due to stricture or tumor (physical cause)
Term
Achalasia
Definition
difficult swallowing food or liquid
loss of peristalsis in lower 2/3
Term
Gastrointestinal bleeding: Hematemesis
Definition
blood in the vomitus
- red blood (higher up in GI Tract)
-coffe ground, crumbly appearance (deeper in GI tract)
Term
Gastrointestinal Bleeding: Melena
Definition
Blood in stool
-red (hemorroids)
-Tarry black: further up in colon and digestive system)
occult (could be hidden or isn't visibly present but can be tested for)
Term
Gastroesophageal Reflux Disease (GERD)
Definition
-back flow of gastric contents into the esophagus through the lower esophageal sphincter (LES)
-erosion in esophagus from acid- metaplasia-cells change to protect from acid
Term
GERD etiology
Definition
fatty foods, caffeine, alcohol, smoking, obesity, progesterone (pregnancy), medications
Term
GERD manifestations
Definition
heart burn, chest pain, regurgitation, dysphagia
may be asymptomatic
Term
Hiatal Hernia
Definition
-Defect in the diaphragm that allows portion of the stomach to rise through the diaphragmatic opening into the thorax cavity
-increasing incidence with age
-associated with ascites, pregnancy, obesity, chronic cough
Term
Esophageal Varicies
Definition
-Dilated blood vessels within the wall of the esophagus
-Diminished liver blood flow causes increased flow through microscopic blood vessels within esophageal wall and vessels dialate
-ASSOCIATED WITH CIRRHOSIS AND PORTAL HYPERTENSION**
- vessel rupture and hemorrhage *death
Term
Gastritis
Definition
inflammatory disorder of the gastric mucosa (stomach)
-Acute and Chronic
Term
Acute Gastritis
Definition
-Transient inflammation of the gastric mucosa
-not as common; short term inflammation
- associated with local irritants such as:
~ bacterial endotoxins
~ alcohol
~ aspirin
Term
Acute gastritis etiology
Definition
~NSAID's
~Aspirin
~bacterial endotoxins
~alcohol
Term
Chronic Gastritis
Definition
-absence of grosly visible erosions
-presence of chronic inflammatory changes
-leads to ATROPHY of glandular epithelium of the stomach
Term
Chronic Gastritis Type A
Definition
-Autoimmune/atrophic (neurological)
~decreased gastric acid
~ few GI symptoms
~ PERNICIOUS ANEMIA
-neurological S&S
- lack of intrinsic factor causing no absorption of vitamin B12
Term
Pernicious anemia
Definition
- decrease in absorption of B12 due to lack of intrinsic factor
Term
Chronic Gastritis Type B
Definition
-chronic inflammation of the stomach lining
~Helicobacter pylori**
- interferes with the protection of the gastric mucosa against acid
-most common
Term
Chronic Gastritis Type B S&S
Definition
-stomach pain, indigestion, looks further inflammed
Term
Peptic Ulcers
Definition
-gastric ulcers (stomach) and duodenal ulcers (first part of small intestine)
-caused my H. pylori** infection
-NSAID (non-steroidal anti-inflammatory drug) [aspirin, ibuprofen]
Term
Peptic Ulcer Manifestations
Definition
- Burning, gnawing pain***
-relieved by food, antacids**
-Epigastric pain
-occurs when stomach is empty (most exposed to acid)
-Epithelial cells get eaten away; erosion and acid will touch area; WBC to destroy bacteria & will destroy whole cell- autoimmune
Term
Duodenal ulcers
Definition
-much more common
-any ages (20-50)
-Type O blood- but also in other blood types
-family history
Term
Gastric Ulcers
Definition
much less common
-older age (55-70)
-no family history
-increased risk of stomach cancer
Term
Complications of peptic ulcers
Definition
HEMORRHAGE- bleeding from tissue or from erosion of ulcer into an artery or vein
OBSTRUCTION- caused by edema, spasm, or contraction of scar tissue and interference with the free passage of gastric contents through the pylorus or adjacent areas (SURGY)
PROTRUSION: ulcer erodes through all layers of stomach or duodenum wall; stomach contents spill into body; irritation and infection; VERY SEVERE***
Term
Pyloric Stenosis
Definition
-narrowing of pylorus due to hypertrophy of surround muscle
-infants 3-12 weeks old
-jewish caucasian male
S&S: Projectile Vomiting**, dehydration, weight loss, WAVES OF PERISTALSIS ACROSS STOMACH
Term
Gastroenteritis
Definition
Inflammation of the stomach and small intestine
-infection organism
-diarrhea throughout night and day, fever**\
-nausea, vomitting, diarrhea, malaise (severe fatigue)
Term
Irritable Bowel Syndrome (IBS)
Definition
-chronic (>3 months) functional disorder with no identifiable pathology
-fluctuations of stool frequency and consistency
-no nocturnal diarrhea** no fever**
-anxiety or depression
Term
Characteristics of IBS
Definition
-persistant or recurrent symptoms of abdominal pain
-altered bowel function (diarrhea or constipation)
-flatulence, bloating
-nausea, anorexia, anxiety or depression
-college students
Term
Constipation
Definition
infrequence or difficult passage of stools
-frequent side effects of narcotics*
-elderly (less active)
-may lead to fecal impaction (serious)
Term
Etiology of constipation
Definition
- failure to respond to urge
-low fiber diet
-low fluid intake
-bed rest/inactivity
-weakness in abdominal muscles
-pregnancy (extra pressure)
-hemorrhoids (painful so try not to)
Term
Fecal Impaction and etiology
Definition
- painful anoretical disease (MANUALLY REMOVE)

-reliance on laxatives*
-use of constipating antiacids
-prolonged bed rest/inactivity
-a low residue diet
-tumors
-neurogenic disease
-drug induced colonic stasis
Term
Inflammatory Bowel Disease (IBD)
Definition
Autoimmune origin
-familial tendency (family diease)
-systemic manifestations
-intermittent (On and off) diarrhea
-RLQ pain
-weight loss
-malaise (fatigue)
Term
Ulcerative Colitis manifestations
Definition
-exudative lesions (produce fluid)
-colon and rectum*
-mucosal layers are infected*
-bloody diarrhea*
-increased risk of COLON CANCER
Term
Crohn's disease
Definition
-Granulomatous lesions (no as acute)
-"cobblestone" appearance (bumpy)
-affects any portion of GI tract
-affects all layers
-no blood in diarrhea
-RLQ pain
-Fistulas common--> inflammation gets deeper and eats away lining of walls
-stenosis (scarring)
Term
Enterocolitis
Definition
Inflammation of Small and large intestines
- pseudomembranous (adults)
-enterocolitis (C. diff)
-necrotizing enterocolitis (infants)
Term
Clostridium Difficile
Definition
-Pseudomembranous***
- associated with antibiotic treatment (kill good bacteria)
-symptoms may be severe
-nosocomial infection
-strong odor, bloody diarrhea**
Term
Necrotizing Enterocolitis
Definition
Acute abdomen in premature newborns
S&S: feeding intolderance, ABDOMINAL DISTENTION, blood stools
areas on bowel become necrotic; without treatment baby will die; SURGERY
inflammation kills small intestine
Term
Intestinal Obstruction: Mechanical
Definition
Physical obstruction blocking bowel
-tumor
-intussusception- bowel folds inside itself
-volvulus- twisting
-hernia-protrusion of organ or tissue
-adhesions- scar tissue
Term
Intestinal Obstruction: Paralytic
Definition
- neurogenic or muscular impairment
-post abdominal surgery
-early peritonitis
Term
Effects of Intestinal Obstruction
Definition
- fluid and gasses get trapped in bowel (bowel is stretch)
-loss of fluid and electrolytes
-compromised mucosal blood flow (necrosis)
-rapid growth of bacteria releasing endotoxins (liquid and partial digestion of food)
-strangulation (hernia), gangrene, perforation of bowel
Term
Manifestations of Intestinal Obstructions
Definition
Pain
absolute constipation
abdominal distention
hyperactive (borborygums- stomach growling loudly) or hypoactive bowel sounds
-vomiting
Term
Diverticulosis
Definition
Herniations of the mucosa through the muscular coat of the colon
out pockets, inflamed, rupture, needs surgery
Term
Diverticulitis
Definition
inflammation of one or more diverticula
food trapped in bubble in outpocket
Term
Etiology of Diverticulitis and presentation
Definition
increase age (70s, 80s, 90s)
low fiber diet

- LLQ pain (sigmoid colon), severe constipation, nausea, fever
Term
Appendicitis
Definition
inflammation, edema, gangrene of appendix
- RLQ
-rebound tenderness
-nausea
-increase in WBCs and fever
-increase in band cells- acute infections cause immature WBCs to become activated
Term
Peritonitis
Definition
-inflammation of peritoneum
Etiology:
- perforated peptic ulcer
-ruptured appendix
-perforated diverticulum
-gangrene bowel
-pelvic inflammatory disease (STD)
-gangrenous gallbladder
-abdominal trauma and wounds- gun shot
Term
peritonitis
Definition
permits rapid absorption of bacterial toxins
favors to dissemination of contaminants (body tries to isolate)
-great inflammatory response causes release of thick, fibrinous exudate
Term
peritonitis manifestations
Definition
-abdominal pain & tenderness
-ridged, board, like adbdomen
-guarding,
-no bowel sounds***
-fever**--> material in GI tract is not sterile so will have bacterial- rais temp to inhibit growth
-tachycardia
-nausea and vomitting
Term
Celiac Disease
Definition
-Digestive disease that damages the small intestine and interferes with absorption of nutrients from food
- cannot tolerate a protein called gluten, found in wheat, rye or barley
-damage to microvilli in SI
Term
Celiac Disease S & S
Definition
- fatty stools, weight loss **
-recurring abdominal bloating and pain, gas, chronic diarrhea, pale, foul-smelling,fatigue
Term
Manifestations of Celiac Disease
Definition
- infancy
-failure to thrive**- not geting enough nutrients
-diarrhea
-abdominal distention**
-occasionally, severe malnutrition
Term
Colon cancer
Definition
3rd most common cancer
occurs over age 50
S&S no early symptoms, later bowel habits change, blood in stool
Term
Colon Cancer- risk factors
Definition
-age
-family history
-ULCERATIVE COLITIS
-chron's disease
-familial adenomatous polypopsis
-diet
Term
Hemorrhoids
Definition
-mass of swollen veins in anus or rectum
-idiopathic

S & S; painful to pass stools; blood in stools
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