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Childhood obesity rising rapidly in all age groups causes Type II Diabeties |
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protein and calorie deficiency |
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protein deficiency (enough calories) |
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Malnutrition and Starvation |
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Skin breaks down, Hair, enlarged liver, edema (swelling) |
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Malnutrition and Starvation Effects |
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-loss of muscle mass -impaired wound healing** -impaired immunologic function-->no proteins to make antibodies (glycoproteins) -decrease appetite -loss of calcium and phosphate from bone -anovulation (not ovulating) & amenorrhea (no menstruating) -decreased testicular function |
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binge eating inappropriate compensatory behaviors (vomit or laxatives of get out of body) |
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-stimulation of the medullary vomiting center -distention of the duodenum -may be accompanied by pallor, sweating, tachycardia, and water salvation |
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-Triggered by vomiting center in medulla -input from GI tact, cerebral cortex, vestibular apparatus (motion sickness, balance in ears (semicircular canal)) -Hypoxia is a strong trigger -may involve the chemoreceptor trigger zone in the fourth ventricle -ADAPTIVE MECHANISM |
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difficult swallowing with a sensation of chocking or food sticking in throat, due to stricture or tumor (physical cause) |
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difficult swallowing food or liquid loss of peristalsis in lower 2/3 |
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Gastrointestinal bleeding: Hematemesis |
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blood in the vomitus - red blood (higher up in GI Tract) -coffe ground, crumbly appearance (deeper in GI tract) |
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Gastrointestinal Bleeding: Melena |
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Blood in stool -red (hemorroids) -Tarry black: further up in colon and digestive system) occult (could be hidden or isn't visibly present but can be tested for) |
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Gastroesophageal Reflux Disease (GERD) |
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-back flow of gastric contents into the esophagus through the lower esophageal sphincter (LES) -erosion in esophagus from acid- metaplasia-cells change to protect from acid |
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fatty foods, caffeine, alcohol, smoking, obesity, progesterone (pregnancy), medications |
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heart burn, chest pain, regurgitation, dysphagia may be asymptomatic |
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-Defect in the diaphragm that allows portion of the stomach to rise through the diaphragmatic opening into the thorax cavity -increasing incidence with age -associated with ascites, pregnancy, obesity, chronic cough |
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-Dilated blood vessels within the wall of the esophagus -Diminished liver blood flow causes increased flow through microscopic blood vessels within esophageal wall and vessels dialate -ASSOCIATED WITH CIRRHOSIS AND PORTAL HYPERTENSION** - vessel rupture and hemorrhage *death |
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inflammatory disorder of the gastric mucosa (stomach) -Acute and Chronic |
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-Transient inflammation of the gastric mucosa -not as common; short term inflammation - associated with local irritants such as: ~ bacterial endotoxins ~ alcohol ~ aspirin |
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~NSAID's ~Aspirin ~bacterial endotoxins ~alcohol |
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-absence of grosly visible erosions -presence of chronic inflammatory changes -leads to ATROPHY of glandular epithelium of the stomach |
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-Autoimmune/atrophic (neurological) ~decreased gastric acid ~ few GI symptoms ~ PERNICIOUS ANEMIA -neurological S&S - lack of intrinsic factor causing no absorption of vitamin B12 |
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- decrease in absorption of B12 due to lack of intrinsic factor |
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-chronic inflammation of the stomach lining ~Helicobacter pylori** - interferes with the protection of the gastric mucosa against acid -most common |
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Chronic Gastritis Type B S&S |
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-stomach pain, indigestion, looks further inflammed |
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-gastric ulcers (stomach) and duodenal ulcers (first part of small intestine) -caused my H. pylori** infection -NSAID (non-steroidal anti-inflammatory drug) [aspirin, ibuprofen] |
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Peptic Ulcer Manifestations |
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- Burning, gnawing pain*** -relieved by food, antacids** -Epigastric pain -occurs when stomach is empty (most exposed to acid) -Epithelial cells get eaten away; erosion and acid will touch area; WBC to destroy bacteria & will destroy whole cell- autoimmune |
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-much more common -any ages (20-50) -Type O blood- but also in other blood types -family history |
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much less common -older age (55-70) -no family history -increased risk of stomach cancer |
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Complications of peptic ulcers |
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HEMORRHAGE- bleeding from tissue or from erosion of ulcer into an artery or vein OBSTRUCTION- caused by edema, spasm, or contraction of scar tissue and interference with the free passage of gastric contents through the pylorus or adjacent areas (SURGY) PROTRUSION: ulcer erodes through all layers of stomach or duodenum wall; stomach contents spill into body; irritation and infection; VERY SEVERE*** |
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-narrowing of pylorus due to hypertrophy of surround muscle -infants 3-12 weeks old -jewish caucasian male S&S: Projectile Vomiting**, dehydration, weight loss, WAVES OF PERISTALSIS ACROSS STOMACH |
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Inflammation of the stomach and small intestine -infection organism -diarrhea throughout night and day, fever**\ -nausea, vomitting, diarrhea, malaise (severe fatigue) |
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Irritable Bowel Syndrome (IBS) |
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-chronic (>3 months) functional disorder with no identifiable pathology -fluctuations of stool frequency and consistency -no nocturnal diarrhea** no fever** -anxiety or depression |
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-persistant or recurrent symptoms of abdominal pain -altered bowel function (diarrhea or constipation) -flatulence, bloating -nausea, anorexia, anxiety or depression -college students |
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infrequence or difficult passage of stools -frequent side effects of narcotics* -elderly (less active) -may lead to fecal impaction (serious) |
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- failure to respond to urge -low fiber diet -low fluid intake -bed rest/inactivity -weakness in abdominal muscles -pregnancy (extra pressure) -hemorrhoids (painful so try not to) |
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Fecal Impaction and etiology |
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- painful anoretical disease (MANUALLY REMOVE)
-reliance on laxatives* -use of constipating antiacids -prolonged bed rest/inactivity -a low residue diet -tumors -neurogenic disease -drug induced colonic stasis |
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Inflammatory Bowel Disease (IBD) |
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Autoimmune origin -familial tendency (family diease) -systemic manifestations -intermittent (On and off) diarrhea -RLQ pain -weight loss -malaise (fatigue) |
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Ulcerative Colitis manifestations |
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-exudative lesions (produce fluid) -colon and rectum* -mucosal layers are infected* -bloody diarrhea* -increased risk of COLON CANCER |
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-Granulomatous lesions (no as acute) -"cobblestone" appearance (bumpy) -affects any portion of GI tract -affects all layers -no blood in diarrhea -RLQ pain -Fistulas common--> inflammation gets deeper and eats away lining of walls -stenosis (scarring) |
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Inflammation of Small and large intestines - pseudomembranous (adults) -enterocolitis (C. diff) -necrotizing enterocolitis (infants) |
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-Pseudomembranous*** - associated with antibiotic treatment (kill good bacteria) -symptoms may be severe -nosocomial infection -strong odor, bloody diarrhea** |
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Necrotizing Enterocolitis |
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Acute abdomen in premature newborns S&S: feeding intolderance, ABDOMINAL DISTENTION, blood stools areas on bowel become necrotic; without treatment baby will die; SURGERY inflammation kills small intestine |
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Intestinal Obstruction: Mechanical |
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Physical obstruction blocking bowel -tumor -intussusception- bowel folds inside itself -volvulus- twisting -hernia-protrusion of organ or tissue -adhesions- scar tissue |
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Intestinal Obstruction: Paralytic |
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- neurogenic or muscular impairment -post abdominal surgery -early peritonitis |
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Effects of Intestinal Obstruction |
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- fluid and gasses get trapped in bowel (bowel is stretch) -loss of fluid and electrolytes -compromised mucosal blood flow (necrosis) -rapid growth of bacteria releasing endotoxins (liquid and partial digestion of food) -strangulation (hernia), gangrene, perforation of bowel |
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Manifestations of Intestinal Obstructions |
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Pain absolute constipation abdominal distention hyperactive (borborygums- stomach growling loudly) or hypoactive bowel sounds -vomiting |
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Herniations of the mucosa through the muscular coat of the colon out pockets, inflamed, rupture, needs surgery |
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inflammation of one or more diverticula food trapped in bubble in outpocket |
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Etiology of Diverticulitis and presentation |
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increase age (70s, 80s, 90s) low fiber diet
- LLQ pain (sigmoid colon), severe constipation, nausea, fever |
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inflammation, edema, gangrene of appendix - RLQ -rebound tenderness -nausea -increase in WBCs and fever -increase in band cells- acute infections cause immature WBCs to become activated |
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-inflammation of peritoneum Etiology: - perforated peptic ulcer -ruptured appendix -perforated diverticulum -gangrene bowel -pelvic inflammatory disease (STD) -gangrenous gallbladder -abdominal trauma and wounds- gun shot |
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permits rapid absorption of bacterial toxins favors to dissemination of contaminants (body tries to isolate) -great inflammatory response causes release of thick, fibrinous exudate |
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peritonitis manifestations |
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-abdominal pain & tenderness -ridged, board, like adbdomen -guarding, -no bowel sounds*** -fever**--> material in GI tract is not sterile so will have bacterial- rais temp to inhibit growth -tachycardia -nausea and vomitting |
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-Digestive disease that damages the small intestine and interferes with absorption of nutrients from food - cannot tolerate a protein called gluten, found in wheat, rye or barley -damage to microvilli in SI |
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- fatty stools, weight loss ** -recurring abdominal bloating and pain, gas, chronic diarrhea, pale, foul-smelling,fatigue |
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Manifestations of Celiac Disease |
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- infancy -failure to thrive**- not geting enough nutrients -diarrhea -abdominal distention** -occasionally, severe malnutrition |
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3rd most common cancer occurs over age 50 S&S no early symptoms, later bowel habits change, blood in stool |
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Colon Cancer- risk factors |
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-age -family history -ULCERATIVE COLITIS -chron's disease -familial adenomatous polypopsis -diet |
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-mass of swollen veins in anus or rectum -idiopathic
S & S; painful to pass stools; blood in stools |
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