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Gallstones and Biliary Tract Disease
Clinical Medicine Test 5
26
Medical
Graduate
11/02/2010

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Cards

Term
What are the two types of gallstones and which one is the most common?
Definition
1) Cholesterol Stones - most common
2) Pigment stones
Term
When are black pigment stones seen?
When are brown pigment stones seen?
Definition
1) black-cirrhosis or hemolytic anemia
2) brown-Asians
Term
What is the most common symptom of billiary stones?
Definition
biliary colic
Term
What is the pain description for gallstones?
Definition
1) localized to epigastrium
2) sudden onset
3) rapidly increasing intensity
4) plateaus and can last for 3 hours
Term
What does pain lasting >6 hours and a fever suggest?
Definition
cholecystitis
Term
What is 90-95% of cholecystitis associated with?
Definition
gallstones
Term
acalculous cholecystitis is more common in whom?
Definition
elderly men who are critically ill following:
1) major surgery
2) severe trauma
3) extensive burns
Term
What are important clinical signs of acute cholecystitis?
Definition
1) tenderness
2) guarding
3) rebound pain
Term
What is the diagnostic test of choice for stones >2mm in size?
Definition
ultrasound
Term
What is the most accurate means of diagnosing acute cholecystitis?
Definition
cholescintigraphy
Term
If febrile in acute cholecystitis what meds should you give?
Definition
broad spectrum 3rd generation cephalosporins
1) ampicillin-sulbactam
2) piperacillin-tazobactam
Term
What are 5 complications of cholecystectomy
Definition
1) localized perforation and abcess
2) empyema
3) emphysematous cholecystitis
4) cholecystenteric fistula
5) gallstones and malignancy
Term
What are 4 groups of people who have a high risk of gallbladder cancer?
Definition
1) Pima Indians
2) Those with calcified gallstones
3) Those with very large stones >3cm
4) gallbladder polyp >10 mm
Term
What is the clinical triad associated with choledocholithiasis?
Definition
1) fever with shaking chills
2) jaundice
3) R upper quadrant colicky pain
Term
What labs rise markedly and abruptly with choledocholithiasis?
Definition
1) serum bilirubin
2) alkaline phosphatase
Term
What diagnostic test shows visualization of stones in 90% of patients?
Definition
ERCP
Term
What should be the initial treatment of choledocholithiasis with a success rate of 97%?
Definition
ERCP sphincterotomy
Term
What are the 5 specific presentations of chronic biliary tract disease?
Definition
1) common bile duct stricture
2) primary sclerosing cholangitis
3) pyogenic cholangitis
4) choledochal cyst
5) sphincter of Oddi dysfunction
Term
What is primary sclerosing cholangitis characterized by?
Definition
1) irregular inflammatory fibrosis of both the intrahepatic and extrahepatic bile ducts
Term
What is present or will develope in 3/4 of patients presenting with primary sclerosing cholangitis?
Definition
chronic ulcerative colitis
Term
What parasites are often found in the stool with pyogenic cholangitis?
Definition
1) opisthorchis sinensis
2) ascaris lumbricoides
Term
What triad exists with choledochal cysts?
Definition
1) abdominal pain
2) mass
3) Jaundice

*fever commonly present
Term
What is biliary colic from gallstones caused by?
Definition
functional spasm of cystic duct
Term
What is Courvoisier's law?
Definition
palpable gallbladder is usually found w/gallstones and malignancy
Term
What is reynolds pentad for choledocholithiasis?
Definition
1) fever w/shaking chills
2) Jaundice
3) R upper quadrant colicky pain
4) Mental Status changes
5) Shock
Term
beeding and pruning of the biliary tree is seen in what?
Definition
primary sclerosing cholangitis
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