Term
Nicotinic receptors (2 types) |
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Definition
NN: autonomic ganglia and adrenal medulla
NM: neuromuscular junction
- both are ligand-gated ion channels |
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Term
Muscarinic Receptors
- 2nd messenger systems |
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Definition
M1, M3, M5: Gq → PLC → DAG + IP3 → PKC
M2, M4: Gi/Go → ↓ adenylate cyclase → ↓ cAMP |
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Term
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Definition
-gastric parietal cells
-peripheral nerves
-some autonomic ganglia (e.g. myenteric plexus) |
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Term
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Definition
-heart
-presynaptic cholinergic neurons |
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Term
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Definition
-exocrine glands
-vascular epithelium
-smooth muscle |
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Term
Muscarinic receptor agonists |
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Definition
Pilocarpine
Bethanchol
Carbachol |
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Term
Muscarinic Receptor Antagonists |
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Definition
Atropine
Ipratropium
Tiotropium
Scopolamine
Pirenzepine
Tolterodine
Oxybutyinin |
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Term
Nicotinic Receptor Agonists |
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Definition
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Term
Ganglionic blocking agents |
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Definition
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Term
Non-depolarizing neuromuscular blockers |
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Definition
d-tubocurarine
Doxacurarine
Rocuronium
Atracurium
Mivacurium |
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Term
Depolarizing Neuromuscular Blockers |
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Definition
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Term
Skeletal Muscle Relaxants |
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Definition
Diazepam
Baclofen
Dantrolene |
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Term
AChE inhibitors used to treat Alzheimers |
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Definition
Tacrine
Donepezil
Rivastigmine
Galantamine |
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