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Nerve cells that carry electrical information |
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provide support for neurons |
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- The brain is composed of individual cells
- Information is transmitted from cell to cell across synapses
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receives information from other cells through dendrites |
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cell body/soma - region where inputs are combined and transformed |
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single axon leads away from the cell body and transmits the electrical impulse |
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axon terminals at the end of the axon communicate activity to other cells |
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most abundant cells in the brain
involved in thinking |
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the stain fills the whole cell but only stain a small proportion of neurons
some cells pick up the chemical (1-2%) |
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Fluorescent Molecule Injections |
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dye fills the whole cell but only stains a small proportion of neurons
glass needle pierces 1 cell and injects dye into it |
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outlines all cell bodies because the dyes are attracted to RNA, which encircles the nucleus |
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shows the distribution of radioactive chemicals (neurotransmitters) in tissues |
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uses radioactive molecules taken up by the cell and then transported to the axon tips
taken up by dendrites and moves down axon to next neuron |
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taken up in the axon terminals and transported to the cell bodies, then visualized through chemical reactions
moves from axon terminals up axon to the cell body |
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- one axon, many dendrites
- most common type
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one axon, one dendrite
Ex: visual system |
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a single extension branches in two directions, forming a receptive pole and an output zone
Ex: somatosensory system |
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stimulate muscles or glands
brain --> body |
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respond to environmental stimuli, such as light, odor, or touch
body --> brain |
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receive input from and send input to other neurons
integrate info from sensory neurons to motor neurons |
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star-shaped glial cells with many processes that receive neuronal input and monitor activity
responsible for blood-brain barrier |
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small glial cells that remove debris from injured cells (part of immune system) |
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the process in which glial cells wrap axons with a fatty sheath to insulate and speed conduction |
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gaps between sections of myelin where the axon is exposed
where electrical signals can happen |
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a demyelinating disease
react slower than normal to stimuli |
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glial cells that form myelin sheath in the central nervous system |
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provide myelin to cells in the peripheral nervous system |
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swelling in the glial cells in response to injury |
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branched pattern neurons have to facilitate contacts |
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a gap that separates the membranes of the presynaptic neuron and the postsynaptic neuron |
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small spheres in presynaptic axon terminals that contain a neurotransmitter |
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specialized proteins in the postsynaptic membrane that react to a neurotransmitter |
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a cone-shaped area of the cell body that gives rise to the axon |
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a branch of an axon that also ends in terminals and innervates other cells |
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the movement of materials within an axon |
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vesicles that pack materials needed throughout neuron and transport them down axon |
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Peripheral Nervous System |
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anything but the brain and spinal cord |
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bundles of axons in the peripheral nervous system |
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nerves connected directly to the brain
- 12 pairs
- can have motor and sensory functions, only motor, or only sensory |
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nerves connected to the spinal cord
- 31 pairs |
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primarily control glands and internal organs |
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Dorsal Root of Spinal Nerves |
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carries sensory information from the body to the spinal cord |
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carries motor information from the spinal cord to the muscles |
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cell bodies, dendrites, unmyelinated axons |
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groups of neurons located outside the CNS |
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neurons that run from the CNS to the autonomic ganglia |
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neurons that run from the autonomic ganglia to targets in the body |
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Sympathetic Nervous System |
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prepares the body for action, excitatory, fight or flight
- has preganglionic neurons only in the spinal cord
- innervate the sympathetic chain, which runs along each side of the spinal cord |
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Parasympathetic Nervous System |
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slows body down, relaxatory
- has preganglionic neurons that arise in the cranial nerves and the sacral spinal cord |
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the outermost layer of the cerebral hemispheres |
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chambers filled with cerebral spinal fluid |
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structure in embryo that develops into the forebrain, the midbrain, and the hindbrain
- forebrain then develops into telencephalon, diencephalon, and mesencephalon |
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becomes the cerebellum and pons
- developed from the hindbrain |
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medulla
- developed from the hindbrain |
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cerebellum, pons, and medulla |
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a collection of neurons in the CNS |
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a bundle of axons in the CNS |
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a collection of neurons in the PNS |
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important in motor control
- 4 nuclei
1. caudate nucleus
2. putamen
3. globus pallidus
4. substantia nigra |
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has structures for learning and memory
1.Amygdala
2. Hippocampus and Fornix
3. Cingulate Gyrus
4. Olfactory Bulb
5. Thalamus
6. Hypothalamus
7. Mamillary Bodies |
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emotional regulation and perception of odor |
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responsible for attention |
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responsible for sense of smell |
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a cluster of nuclei that relay sensory information |
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contains nuclei with many functions; also controls the pituitary |
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processes visual information |
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processes auditory information |
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superior and inferior colliculi |
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communicates with motoneurons in the spinal cord |
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involved in motor coordination and learning
Three layers:
1. Molecular (top)
2. Purkinje Cell (what gets messed up with alcohol)
3. Granule Cell |
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attached to the cerebellum and contains motor and sensory nuclei and gives rise to cranial nerves |
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contains cranial nerve nuclei and marks the transition from brain to spinal cord |
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three protective membranes that surround the brain and spinal cord |
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1. Dura Mater
2. Arachnoid Membrane (filled with cerebrospinal fluid)
3. Pia Mater |
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1. acts as a shock absorber
2. provides an exchange medium between blood and brain |
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a membrane that produces CSF |
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a structure formed by the major cerebral arteries |
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caused by the rupture or blockage of blood vessels, leading to insufficient blood supply |
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keeps blood from mixing with structures in the brain
- results from higher resistance in brain capillaries that restricts passage of large molecules
- glial cells transport materials from blood vessels to neurons |
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X-ray of head with dye present in cerebral blood vessels |
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Computerized Axial Tomography (CAT scan) |
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a measure of X-ray absorption at several positions around the head
- maps tissue density |
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Magnetic Resonance Imaging (MRI) |
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gives higher resolution images
1. strong magnets cause protons in brain tissue to line up in parallel
2. A pluse of radio waves knocks protons over
3. Protons reconfigure themselves, emitting radio waves that differ by tissue density |
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Positron Emission Tomography (PET) |
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gives images of brain activity
- uses radioactive chemicals injected into the bloodstream and maps their destination by the radioactive emission
- identifies which brain regions contribute to specific functions |
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detects small changes in brain metabolism, such as oxygen use, in active brain areas |
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uses near-infrared light passed through the skull to reveal brain activity |
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Transcranial Magnetic Stimulation (TMS) |
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briefly stimulates discrete cortical regions with magnets |
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Magnetoencephalography (MEG) |
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measures the tiny magnetic fields given off by active neurons |
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