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F. Smith- Malaria and others
Malaria and others
30
Pathology
Graduate
10/25/2009

Additional Pathology Flashcards

 


 

Cards

Term
What decreases the severity/occurrence in malaria infection?
Definition

lack of Duffy blood group factor

have sickle cell trait and HbC

have G-6-PD deficiency

Term
What is a secondary affect of hemolytic anemia with malaria?
Definition

jaundice

 

Term
What are symptoms of malaria?
Definition

hepatosplenomegaly

headache

myalgia

nausea

delirium

fever

chills

Term
what is blackwater fever?
Definition

plugging of tubules and acute tubular necrosis from massive hemolysis (Malaria)

Term
Death in adults with malaria is associated with?
Definition

ARF

cerebral malaria

DIC

Term
What are the classical pathogenic features of malaria?
Definition

-hemolytic anemia and complications

-malarial pigment in spleen/liver

-capillary plugging in brain

Term
Which strain of plasmodium will be more likely to be in the trophozoite form?
Definition
P. vivax
Term

Which strain of plasmodium will be more likely to be in the gametocyte (banana) form?

Definition
P. falciparum
Term
What disease is acquired by ingestion of cyst stage or organism in raw or improperly cooked meat
Definition
toxoplasmosis
Term

What is the morphology of toxoplasmosis?

Definition
macrophages, containing trophozoites of organisms, necrosis, vascular thromsis, calcification
Term
How do you Dx toxoplasmosis?
Definition

-look at CSF, pleural, peritoneal fluid for organisms

-serology for Ab by SABIN FELDMAN dye test

Term

What does

T. rhodendiense

and T. gambiense cause?

Definition
Trypanosomiasis
Term

Trypanosomiasis

causes?

Definition

fever

hyperplasia of RE system

inflammation of brain

 

Term
What is the American type of Trypanosomiasis?
Definition
Chaga's disease
Term
How is Chaga's disease transmitted?
Definition
reduviid or kissing bug
Term

Trypanosomiasis can result in what chronic manifestations?

Definition

heart failure from inflammation and scarring/

nerve damage at esophagus and colon/

magaesophagus or megacolon

Term
what is the name for a pinworm?
Definition
Enterobius vermicularis
Term
What is the name for a roundworm?
Definition
ascaris lumbricoides
Term
Can a round worm reach the lungs?
Definition
yes
Term
what is a hookworm called?
Definition

Necator americus

or

Ancyclostoma duodenale

Term
can a hookworm go to the lungs?
Definition
yes
Term
what is the name for a tapeworm?
Definition

Taenia saginata

Taenia solium

Diphyllobothrium latum

Term
Diphyllobothrium latum can cause megaloblastic anemia because?
Definition
it competes with Vit B12
Term
How can you get a liver fluke?
Definition

under cooked, salted, pickled, or smoked freshwater fish-Clonorchis sinensis

or watercress-Fasciola hepatica

Term
What are the different bugs for Schistosomiasis?
Definition

S. japonicum

S. haematobium

S. mansoni

Term

lesions caused by 

S. japonicum and

S. mansoni?

Definition

colon 

liver

Term

lesions caused by 

S. haematobium

are where?

Definition
urinary bladder--may get squamous cell carcinoma (usually transitional)
Term
which bug only develops in striated muscle and can cause fever, muscle tenderness, swelling of eyelids, and eosinophilia?
Definition

Trichinosis

 

(trichinella spiralis)

Term
What does Wuchereria bancrofti cause?
Definition
Elephantiasis
Term
What is the vector for Elephantiasis?
Definition
Culex mosquito
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