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Definition
| Synthesis of RNA using information in the DNA |
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Definition
| Pries the 2 DNA strands apart and joins together RNA nucleotides complementary to the DNA template strand, thus elongating the RNA polynucleotide |
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Definition
DNA sequence where RNA polymerase attaches and initiates transcription
Defines which strand is template strand |
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Definition
| Sequence that signals end of transcription - tells the cell "this is the end of a gene" |
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Definition
| Promotor brings in transcription factors,transcription factors bring in RNA ploymerase, DNA strands unwind, and the polymerase intiates RNA synthesis at the start point on the template strand |
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Term
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Definition
| Mediate the binding of RNA polymerase and the initiation of transcription |
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Term
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Definition
| RNA polymerase opens up loop of ~20 nucleotides, reads open nucleotides, and brings in incoming nucleotides and adds them to the 3' end |
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Term
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Definition
| RNA Pol II transcribes a polyadenylation signal in the pre-mRNA. ~10-35 nucleotides downstream, proteins associated with growing RNA transcript cut it free from the polymerase, releasing the pre-mRNA. Pre-mRNA undergoes processing |
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Term
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Definition
Only found in mRNA
HIghly conserved: AAUAAA
Polymerase travels past the signal |
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Term
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Definition
| 5' end is capped. Modified form of Guanine (G) nucleotide is added to 5' end |
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Term
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Definition
3' end is polyadenylated.
AAUAAA signal is recognized, RNA is cleaved, and ~200 Adenines (A) are added (Poly A tail) |
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Term
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Definition
| RNA splicing - introns are removed |
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Term
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Definition
| Large stretch of non-coding sequence that must be removed before the RNA is functional |
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Term
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Definition
| The coding sequences. Eventually expressed, usually by being translated into amino acid sequences. Exit the nucleus |
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Term
| Small nuclear ribonucleoproteins |
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Definition
| Recognize splice sites. Compex of RNA and proteins |
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Term
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Definition
| Several different snRNPs join with additional proteins |
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Term
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Definition
| RNA molecules that function like enzymes |
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Term
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Definition
| Discrete functional and structural regions |
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