Term
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Definition
| Is the process by which a drug is transferred from its site of entry into the body to the bloodstream. |
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Definition
Undesirable effects other than the intended therapeutic effect of a drug.
- some adverse drug effects are predicitable.
- example: Morphine causes constipation.
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Term
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Definition
| Is an immune system response that occurs when the body interprets the administered drug as a foreign substance and forms antibodies against the drug. |
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Term
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Definition
| Is a glass flask that contains a single dose of medication for parenteral administration. |
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Definition
| Life threatening and results in respiratory distress, sudden severe bronchospasm, and cardiovascular collapse. The reaction is treated with Vasopressors, bronchodilators, corticosteroids, oxygen therapy, IV fluids, and antihistamines. |
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Term
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Definition
| Same as previous flash card. |
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Term
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Definition
In a drug-drug interaction, the combined effect of two or more drugs acting simulataneously produces an effect either less than that of each drug alone.
- Or greater than that of each drug alone would be
Synergistic Effect |
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Term
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Definition
| Occurs when the body Cannot metabolize one dose of a drug before another dose us administered. The drug is taken in more frequently than it is excreted, and each new dose increases the total quantity in the body. |
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Term
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Definition
After a drug has been absorbed into the bloodstream, it is distributed throughout the body.
Distribution depends on the blood flow to the tissues, the drug's ability to leave the bloodstreamm and the drug's ability to enter the cells. |
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Term
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Definition
| Occurs when the body becomes accustomed to the effects of a particular drug over a period of time. |
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Term
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Definition
| After the drug is broken down to an inactive form, excretion of the drug occurs. Excretion: is the process of removing a drug, or its metabolites (products of metabolism), from the body. Usually by the kidneys, but can occur in the lungs and through bile. |
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Term
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Definition
| Which identifies the drug's active ingredient, is the name assigned by the manufacturer that first develops the drug. |
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Term
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Definition
| Is the amount of time it takes for 50% of the blood concentration of a drug to be eliminated from the body. |
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Term
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Definition
AKA: Paradoxical Effect
is any unusual or peculiar response to a drug that may manifest itself by over response, under response, or even
the opposite of the expected response. These effects are related to a patiens unique response to a drug and are thought to be the result of genetic enzyme deficiencies that lead to an abnormal mechanism of drug break down. |
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Term
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Definition
| Are aerosolized, delivered in smal particles, and breathed in by a patient. |
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Term
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Definition
Are administered into the dermis, just below the epidermis. The intradermal route has the longest absorption time of all the parenteral routes.
- These type of injections are used for sensitivity tests, such as tuberculin and allergy tests, and local anesthesia.
- Pg. 749 has the equipment needed for this injection.
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Term
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Definition
| Deliver medications through the skin and subcutaneous tissues into certain muscles. This route is used to administer drugs such as anti-biotics, hormones, and vaccines. |
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Term
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Definition
| Is the most dangerous route of administration because the drug is placed directly into the bloodstream, it cannot be recalled, and its actions cannot be slowed. |
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Term
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Definition
| Or biotransformation, is the change of a drug from its original form to a new form. The liver is the primary site for drug metabolism. Other tissues such as the GI tract, lungs, kidneys, and skin also have a role in drug metabolism. |
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Term
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Definition
(syringe pump) for intermittent infusion is battery operated and allows medication mixed in a syringe to be connected to the primary line and delivered by mechanical pressure applied to the syringe plunger
(see skill 29-9) |
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Term
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Definition
| Is the name by which the drug is identified in the official publications, United States Pharmacopeia and Nations Formulary (USP and NF). The official name is often the generic. |
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Term
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Definition
| Means outside the intestines or alimentary canal/ Several methods to administer a medication by the parenteral route involve injecting the medication into those body tissues outside of the intestines or alimentary canal and into the circulatory system. |
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Term
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Definition
| Or highest plasma concentration, of the drug should be measured when absorption is complete. The peak level may be affected by factors that affect drug aborption as well as the routeof administration. |
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Term
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Definition
| The process by which drugs alter cell physiology and affect the body. |
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Term
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Definition
| Is the effect of the body on the drug. It is the movement of drug molecules in the body in the relation to the drug's absorption, distribution, metabolism, and excretion. |
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Term
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Definition
| The study that deals with chemicals that affect the body's functioning. |
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Term
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Definition
| The goal of the drug dosing is to give a dose that achieves the desired therapeutic effect of that drug without causing other undersirable effects. |
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Term
Piggyback Delivery
System |
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Definition
| IV: Requires the intermittent or additive solution to be placed higher than the primary solution container. |
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Term
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Definition
| Pharmacologically inactive substance. |
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Term
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Definition
| A physcian may write a prn order "as needed" for a medication. |
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Term
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Definition
| Also is a single orderm but it is carried out immediately. |
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Term
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Definition
| Are administered into the adipose tissue layer just below the epidermis and dermis. This tissue has few blood vessels, so drugs administered here have a slow, sustained rate of absorption into capillaries. This route is ued to administer drugs such as insulin and heparin. |
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Term
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Definition
| In a drug-drug interaction the combined effect of two or more drugs acting simultaneously produces an effect greater than that of each drug alone. |
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Term
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Definition
| Are known to have the potential to cause developmental defects in the embryo or fetus and are definitely contradicted. |
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Term
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Definition
| Is the concentration of drug in the blood serum that produces the desired effect without causing toxicity. |
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Term
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Definition
| Are usually intended for direct action at a particular site, although some can have systemic effects and are given for systemic affect. The action depends on the type of tissue and the nature of the agent. |
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Term
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Definition
| Are specific groups og symptoms related to drug therapy that carry risk for permanent damage or death. |
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Term
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Definition
| Also referred to as the brand name or proprietary name, is selected by the drug company that sells the drug and is protected by trademark. |
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Term
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Definition
| Is the point when the drug is at its lowest concentration, and the specimen is usually drawn in the 30-minute interval before the next dose. |
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Term
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Definition
| Is a glass bottle with a self-sealing stopper through which medication is removed. |
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Term
Volume-Control Administation
Set |
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Definition
| For intermittent intravenous infusion. The medication is diluted with a small amount of solution and administered through the PT IV. |
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Term
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Definition
| Is recommended for all intramuscular injections to ensure medication does not leak back along the needle track and into the subcutaneous tissues. |
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