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FNU Exam 5 part 2
BBC lecture- Final exam, yaaaaaayyyyy!!!!!!!!!!!!!!!!!!
104
Pathology
Graduate
12/15/2012

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Term
This type of diarrhea occurs when non-absorbale substances in the bowel draw water into the bowel in large volumes
Definition
osmotic
Term
This type of diarrhea is excessive mucousal fluid and secretions that seep into the bowel and stool
Definition
secretory
Term
Secretory diarrhea is usu caused by
Definition
bacteria
Term
When food is not mixed properly, digestion is impaired which leads to which type of diarrhea
Definition
motility
Term
Motility diarrhea is associated with
Definition
resection of the small bowel and diabetic neuropathy
Term
In abd pain, the organs are most sensitive to
Definition
stretch
Term
Mechanical abd pain is r/t bowel distention caused by
Definition
gas, fluid, stool, or air
Term
A swollen liver may aslo caused
Definition
abd pain
Term
This type of abd pain is caused by infection by bacteria, parasites, or fungus
Definition
inflammatory
Term
Ischemic abd pain is caused by
Definition
decreased blood flow
Term
This type of abd pain is localized and intense. It comes to the skin and is close to the surface of the body
Definition
parietal
Term
This type of abd pain is derived from abd organs, usu poorly localized, and carried by sympathetic nerve fibers
Definition
viscera
Term
This type of abd pain is felt at some distance from the disease organ and is due to shared spinal segment
Definition
referred
Term
Upper GI tract bleeding is often associated with
Definition
hematemesis
Term
Lower GI tract bleeding causes
Definition
melena, hematochezia, occult bleeding
Term
Melena is
Definition
black tarry stools
Term
Hematochezia is
Definition
bleeding close to the rectum or anal area
Term
GER causes digested food to ________
Definition
erode the esophagus
Term
Anything that increases abd pressure or weakens the ______ causes ________
Definition
lower esophageal spinchter and GER
Term
One way Lower esophageal spinchter weakness may occur is due to
Definition
an increase in progesterone

*usu associated with pregnancy
Term
clinical manifestations of GER include
Definition
reflux, heart burn, asthma, and upper abd pain within 1hr of eating
Term
A break or ulceration in mucosal lining of the lower esophagus, stomach, or duodenum
Definition
Peptic ulcer disease
Term
What is the most common peptic ulcer disease?
Definition
duodenal ulcers
Term
Risk factors like excessive NSAID use, alcohol intake, or chronic disease are associated with
Definition
PUD
Term
The most common causes of duodenl ulcers are
Definition
H pylori and NSAID usage
Term
_______ inhibit prostaglandis which are needed to protect the mucosal barrier in the stomach
Definition
NSAIDs
Term
In PUD, pain most commonly occurs when
Definition
the stomach is empty
Term
Pain from PUD is relieved by
Definition
antacids and food
Term
Exacerbations in PUD is seen in the
Definition
spring and fall
Term
_______ occur in the upper portion of the stomach
Definition
gastric ulcers
Term
Gastric ulcers occur among ______ males and females
Definition
55-65yr old
Term
Major causes of gastric ulcers
Definition
nsaids and h pylori and chronic gastritis
Term
In gastric ulcer disease, the primary defect is an abnormality in__________ to
Definition
mucosal barrier permeability and hydrogen ion
Term
with gastric ulcers, pain may occur
Definition
immediately after eating a meal
Term
Pts with gastric ulcers may get______ more rapidly
Definition
full
Term
Dumping syndrome, alkaline reflux, afferetn loop obstruction, diarrhea, weight loss, anemia, and bone disorders are r/t
Definition
post-gastrectomy syndromes
Term
Rapid emptying or partially digested food is called
Definition
dumping syndrome

*this causes osmotic diarrhea
Term
Reflux of bile and pancretic secretions into the stomack is called
Definition
alkaline reflux gastritis
Term
When the volvulus intestines invaginates into other parts of the intestine
Definition
afferent loop obstruction
Term
Afferent loop obstructions cause
Definition
adhesions, avulsions, and duodenol stomps

*requires surgical interventions
Term
Ulcerative colitis is less common in
Definition
smokers

*this is not a risk factor
Term
Ulcerative colitis most commonly affects which parts of the colon?
Definition
rectum and sigmoid
Term
Ulcerative colitis begins to present itself usu between ages
Definition
20-40
Term
In ulcerative colitis, there may be periods of _______________ which may be mild or severe.
Definition
remission and exacerbation
Term
People with anemia r/t to post-gastrectomy syndromes may experience
Definition
macrocytic anemia

*Vit B12 and folate deficiency
Term
Heriniations or saclike outpouchings of the mucosa throught the muscle layers of the sigmoid colon is called
Definition
diverticular disease
Term
Diverticular disease is casued by an ________ in susceptible inidividuals.
Definition
increase in internal bowel pressure
Term
Eating lots of processed foods with little fiber increases the risk of developing
Definition
diverticular diease
Term
Stool may be trapped inside of the diverticuli which leads to________ called
Definition
infection and diverticulitis
Term
If and infected diverticuli ruptures, you can get
Definition
peritinitis
Term
Other than constipation, diverticulitis is
Definition
asymptomatic
Term
Diverticular disease is most commonly seen in what age group?
Definition
elderly
Term
These clinical manifestations, vague or absent, constipation, diarrhea, increased SBCs, and left lower quadrant pain, are some symptoms associated with
Definition
diverticular disease
Term
name the most common surgical emergency
Definition
appendicitis
Term
Appendicitis is most commonly seen in which age group?
Definition
20-30yr olds may occur at any age
Term
This condition is caused an obstruction in the lumen with stool, tumor, or a foreign body
Definition
appendicitis
Term
Burney's point is pain located in the __________ of the abd and is seen in _____
Definition
RLQ and appendicitis
Term
IBS is a _______ bowel disorder that is most common in _____
Definition
fuctional and women
Term
The most common age for IBS is
Definition
45-50 though younger women are seen with the disorder
Term
Though the exact cause of IBS is unknown, some theories suggest
Definition
emotional stress, gluten intolerance, intestinal infection, or overgrowth of the intestinal flora may contribute to the condition
Term
IBS may have abd discomfort relived by _________, _________, or _________/
Definition
BM, gas/bloating, diarrhea/constipation
Term
Obesity is a ________ is a major risk for
Definition
metabolic disorder and morbidity and mortality
Term
Leptins are hormones produced by fat cells that help
Definition
decrease appetitte
Term
When an excess of fat cells are produced, there is an overproduction of __________ causes__________
Definition
leptin and overeating
Term
People with anorexia, have a body weight which is
Definition
15% less than normal for their height and weight
Term
Dx of anorexia involves taking a thorough_________, ____________, and _______ evaluation
Definition
hx, physical exam, psychological
Term
Person with anorexia, typically have complications with __________ due to not eating
Definition
cardiac failure
Term
Dx of bulemia is based on at least ________ binge eating episodes per week for_____
Definition
2 and 3months
Term
person with bulemia, will typically fast to offset
Definition
binge eating
Term
Name three types of juandice
Definition
obstuctive, intrahepatic, and excessive hemolysis
Term
when conjugated bilirubin cannot flow thus accumulating and entering and the blood, this is called
Definition
obstuctive juandice
Term
_________ change conjugated bilirubin to make it water soluble
Definition
hepatocytes
Term
this type of juandice occurs when conjugated and unconjugated bilirubin increase
Definition
intrahepatic

*problem with hepatocytes
Term
this type of juandice occures when there is an increase in unconjugated bilirubin
Definition
excessive hemolysis
Term
unconjugated bili is not metabolized by
Definition
hepatocytes
Term
in utero, NBN have a high
Definition
H and H
Term
After birth, nbn, dont need an excess of Hbg which leads to a breakdown of of RBCs which causes
Definition
physiologic juandice
Term
ways to remedy nbn juandice is through
Definition
food
*breastmilk or formula
Term
cholelithiasis is most common in
Definition
women
Term
Cholelithiasis is _______ and cholecysitis is
Definition
gallstones and inflammation of the gallbladder
Term
Risk factors for gallbladder disease include the 5 "f's" which are
Definition
fair, fat, forty, fertile, and female
Term
95% of all cases of cholecystitis is caused by
Definition
gallstones
Term
Pregnancy, use of oral contraceptives, HRT, and Native American heritage are also risk factors for
Definition
gallbladder diease
Term
Pt with gallbladder disease will exhibit a positive
Definition
murphy's sign
Term
This sign is demonstrated when the provider applies pressure over the liver and the pt is unable to take a deep breath in due to discomfort
Definition
murphy's sign
Term
In gallbladder disease, pt will present with juandice due to
Definition
excess of conjugated bilirubin
Term
This disease is caused by alcoholism and/or gallstones in the ampulla of vater that causes an obstuction and reflux of pancreatic enzymes and autodigestion of the pancrease
Definition
acute pancreatitis
Term
Name one enzyme seen in reflux with people dx with acute pancreatitis
Definition
tripsin
Term
acute prancreatitis may result in __________ or _______
Definition
acute organ failure or death
Term
Severe abd pain, fever, n/v, hypotension, abd distention, and shock may be seen in individuals with
Definition
acute pancreatitis
Term
this conditions is when the esophagus ends in a bind pouch
Definition
esophageal atresia
Term
mothers with polyhydramnios,nbn with pulmonary issues, and poor feeding are often seen in nbn who have
Definition
esophageal atresia
Term
infants with pyloric stenosis will exhibit
Definition
projectile vomiting

*may also be failure to thrive
Term
Pyloric stenosis is seen is
Definition
white, full term, male infants
Term
Upon assessment of infants with pyloric stenosis, a ________ is palapable
Definition
firm mass
*requires surgery to repair
Term
this is outpouching of the all the layers of the small intestinal wall
Definition
meckel diverticulum
*usu asymptomatic
Term
Meckel Diverticulum is the most
Definition
common congenital GI malformation
Term
Meckel diverticulum usu affects
Definition
males
Term
the most common symptom of meckel diverticulum is
Definition
painless rectal bleeding
Term
people with symptoms of meckel diverticulum will usu present by _______ or __________
Definition
age 2 or adulthood
Term
Gerd occurs in most _________infants and is due to delayed ________ of the lower esophageal spinchter
Definition
premature and maturation

*may also occur in impaired hormone repsonses
Term
CM of Gerd in infants may be
Definition
excessive vomiting, failure to thrive from 1-6wks of life, or aspiration pneumonia
Term
this is an absence or obstruction of the intrahepatic or extra hepatic bile ducts
Definition
biliary atresia
Term
CM of this condition include gray colored stools(acholic stools), juandice at birth, hepatomegaly, cirrhosis
Definition
biliary atresia
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