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FNU Exam 3 Study guide
na
53
Pathology
Graduate
11/12/2012

Additional Pathology Flashcards

 


 

Cards

Term

Anemia rfers to a deficiency of

 

 

 

 

a. blood plasma

b. erythorcytes

c. platelets

d. hemoglobin

e. both b and d

Definition
E
Term

Etiologic classification of anemia is based on

 

 

 

 

a. size

b. color

c. shape

d. decreased defective errythorcytes

Definition
D
Term

Tissue Hypoxia causes

 

 

a. arterioles, capillaries, and venules to contrict

 

b. the heart to contract less forcefully

 

c. the rateand depth of breathing to increase

 

d. inreased afterload

Definition
C
Term

Which of the following symptoms are consistent with aplastic anemia but not with perincious anemia?

 

a. petechiae and purpura

 

b. pallor

 

c. fatigue

 

d. hypoxia

 

e. neuropathy

Definition
A
Term

I a reticulocyte count were done on an individual with iron deficiency anemia ecasue of chronic bleeding, it would be

a. high

 

b. low

 

c. normal

 

d. meaningless

 

 

Definition
A
Term

A 40-yr old white, pregnnt woman with four children experrienced weakness, loss of appetite, and pallor. Her CBC revealed the following:

 

Macrocytic RBCs 2.5 x 10/mm

H and H 8.7 and 32

She most likely has:

a. sickle cell anemia

 

b. floicacid anemia

 

b. iron deficiency anemia

 

d. pernicious anemia

 

Definition
B
Term

A cause of macrocytic-normochromic anemia is

a. iron deficiency

 

a.b deficiency of vit B12 and folic acid

 

c. an enzyme deficiency

 

d. inferitance of abnormal hemoglobin structure

 

Definition
B
Term

Hemolytic anmei may result i

 

a. jaundice

 

b. loss of vibratory sense

 

c. acidosis

 

d. peechiae

Definition
A
Term

The end result of anemia is

 

a. anoxia

 

b. hypoxia

 

c. infection

 

d. bleedidng

 

e. hypoxemia

 

Definition
B
Term

An individalwho has chronic gastrtis and tingling in his or her fingres requires which of the followig for tx?

 

a. oral vit B12

 

b. Vit B12 IM

 

c. Ferrous fumarate by IM injectin

 

d. Oral folate

 

e. tranfusion

Definition
B
Term

Individuals at risk for inron deficiency anemia include those:

 

a. who have udergone a gastrectomy

 

b. who are Italian

 

c. with neoplastic disease

 

d. with warm antibodies

 

e. with minor, chronic blood loss

Definition
E
Term

The symptoms of sideroblastic anemia may include:

 

a. glossitits

 

b. hepatomegaly and splenomegaly

 

c. bleeding and recurrent infections

 

d. neuropathy

 

e. juandice

Definition
B
Term

The pathophysiology  of polycythemia vera is essentialy caused by

 

a. fewer erythrocytes than normal

 

b. decreased blood volume

 

c. an acquire mutation in Janus kinase 2

 

d. increased rate of blood flow

Definition
C
Term
Vit B12 deficiency is
Definition
macrocytic-normochromic
Term
Iron deficiency
Definition
microcytic-hypochromic
Term
Folic Acid  Deficiency
Definition
Macrocytic-normochromic
Term
Bone marrow depression
Definition
normocytic-normochromic
Term
Chronic infection
Definition
normocytic-normochromic
Term
hemolysis
Definition
normorcytic-normochromic
Term
posthemorrhagic
Definition
normocytic-normochromic
Term
Decreased heme synthesis
Definition
microcytic-hypochromic
Term
chloramphenicol therapy
Definition
microcytic-hypochromic
Term
malignancy
Definition
normocytic-noromochromic
Term

What is anotable characteristic of infectious mono?

 

a. short incubationperiod of less than 1 week

 

b. affects preteens

 

c. presece of atypical lymphocytes

 

d. widespread nvasion of T cells

Definition
c. presece of atypical lymphocytes
Term

Thrombocytopenia may be caused by all of the following except:

 

a. an IgG autoantibody

 

b. drug hypersentivity

 

c. bacerial infectionns that consume platelet production

 

d bacterial infections taht consume platelets

 

e. viruses that destry circulation platelets

Definition
c. bacerial infectionns that consume platelet production
Term

A thromobocytopenia with a platelet count of 40,000/mm likely will cause

 

a. hemorrhage from minor trauma

 

b. spontaneous bleeding

 

c. death

 

d. polycythemia

Definition
a. hemorrhage from minor trauma
Term

Thrombembolic disorders can be caused by all of the following except:

 

a. injure vessels walls

 

b. tissue damage that releases xcessive TF

 

c. obstructd blood flow

 

d. deficent dietary intake of Vit K

 

e. polycytemia

Definition
d. deficent dietary intake of Vit K
Term

Essential thromobocythemia exhibits:

 

a. fewer megakaroytes than normal in the marrow

 

b. thrombosis

 

c. erythromyalgia

 

d. B and C

 

 

Definition
d. B and C
Term

DIC is associated with

 

a. endothelial damage

 

b. the activation of factor X

 

c. the release of tissue factor

 

d. gram postive sepsis

 

e. A, B, and C

Definition

e. A, B, and C

Term

In DIC, plasmin:

 

a. begins to degreade fibrin before a stable clot develops

 

b. complexes with factor VII

 

c. activates factor V

 

d. All of the above 

Definition
a. begins to degreade fibrin before a stable clot develops
Term
What causes eosinophilia?
Definition
allergic disorders
Term

A defienciency of Vit K is caused by:

 

a. lack of clotting factore VII

 

b. impaired platelet fx

 

c. altered gut flora

 

d. A and B are correct

Definition
c. altered gut flora
Term
T or F During fetal life the synthesized hemoglobin is composedof two alpha and two beta chains
Definition
False
Term
T or F Although a frequent problem, ABO incompatibility seldom results in significant disease
Definition
True
Term
T or F Sequestration is a serious complication of sickle cell disease seen only in the young child
Definition
true
Term
T or F Rh incompatibility is a problem only of Rh+ women bearing an Rh- fetus during a scond pregnancy
Definition
False
Term
T or F Because hemostasis in the newborn is chiefly attained through the extrinsic pathay, seious bleedig in the newborn period is us not a problem in hemophiliacs
Definition
True
Term
T or F Idiopathc thrombocytopenic purpura is a genectically transmitted disease
Definition
False
Term
The blood disorder of infancy and childhood caused by poor dietary iron intake is:

a. a microcytic-hypochromic anemia
b. pernicious anemia
c. folate deficiency anemia
d.sideroblasitc anemia
Definition
A a microcytic-hypochromic anemia
Term
A firt time pergnancy may initiate Rh sensitization in which conditions?

a. Rh+ mother, RH- fetus
b. Rh- mother, Rh+ fetus
c. Rh- father, Rh+ mother
d. Rh- father Rh- mother
Definition
B. Rh- mother and Rh+ fetus
Term
Beta-thalassemia is

a. common among Italians
b. an X-linked recessive disorer
c. an autosomal dominant disorde
d. common in Chinese
e. A and C
Definition
A. common among Italians
Term
Sickle cell disese is an:

a. autosomal dominant disorder
b. X-linked recssive disorder
c. X-linked dominant disorder
d. autosomal recessive disorders
Definition
D. autosomal recessive disorder
Term
Iodiopathic thrombocytopenic purpura (ITP) involves:

a. neutrophilic destruction
b. eosinophilic destruction
c. platelet/antibody complex
d. thrombocytosis
Definition
C. platelet/antibody complex
Term
Which are associated with inherited thrombophilic conditions?

a. antithrombin III deficiency
b. Factor III deficiency
c. ecreased platelet adhesiveness
d. A and C
Definition
A. Antithrombin III deficiency
Term
Which is the most likely cause of idiopathic thrombocytopenic purpura?

a. Stress and fatige
b. high levels of IfF on platelets
c. prolonged occult bleeding
d. viral sensitization
Definition
D Viral sensitization
Term
In sickle cell disease, vaso-occlusive crisis is the result of:

a. damage to platelets due to IgG
b. the "plugging" of peripheral blod vessels by "stiff" sickled erythrocytes
c.the ingestion of sulfa drugs
d. sequestration of large numbers of erythrocytes in the spleen
Definition
B. the "plugging" of peripheral blod vessels by "stiff" sickled erythrocytes
Term
Causes urate precipitates in renal tubules
Definition
leukemia
Term
Causes antibody/cell coplexes sequester in the spleen
Definition
ITP
Term
Sensitization usu required before problems develop
Definition
sickle cell anemia
Term
May present early as symmetric, painful swellig of the hands and feet
Definition
sickle cell anemia
Term
May cause severe hemolysis during the newborn period
Definition
Rh incompatibility
Term
May result in aplastic crises
Definition
sickle cell anemia
Term
May result in hydrops fetalis or fetal death
Definition
Rh incompatibility
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