Term
Intracellular compartments make up how much of fluid compartments? |
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Definition
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Term
Most abundant ion in extracellular fluid |
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Definition
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Term
Ion that has the most influence over movement of other solutes and water |
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Definition
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Term
Electrolyte that generates action potentials in nerve and muscle tissue |
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Definition
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Term
Sodium is under hormonal control of? |
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Definition
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Term
Most abundant anion in ECF |
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Definition
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Term
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Definition
reabsorbed by tubules along with sodium |
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Term
Most abundant cation in the ECF |
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Definition
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Term
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Definition
Helps maintain RMP, intracellular fluid and pH balance |
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Term
Potassium is under the control of which hormone? |
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Definition
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Term
Chloride is under the control of which hormone? |
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Definition
Aldosterone (reabsorbed by tubules along with sodium) |
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Term
When do bicarbonate levels in blood increase? |
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Definition
flowing through systemic capillaries |
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Term
When do bicarbonate levels in blood decrease? |
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Definition
after flowing through pulmonary capillaries |
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Term
When pH is high, what do Intercalated cells do? |
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Definition
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Term
When pH is low, what do Intercalated cells do? |
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Definition
Excrete bicarbonate when pH levels are low |
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Term
Most abundant mineral in the body |
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Definition
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Term
Calcium is under the hormonal control of? |
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Definition
PTH, Calcitriol, Calcitonin |
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Term
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Definition
Important for blood clotting, nerve signals and muscle contraction |
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Term
Important H+ buffer in body fluids and urine |
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Definition
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Term
phosphate is under the hormonal control of? |
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Definition
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Term
What is the response of intercalated cells to H+ when pH is high? |
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Definition
Excrete H+ when pH is high |
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Term
Intercalated discs method of excreting bicarbonate when pH is low |
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Definition
Proton pumps (H+ ATPases) Cl-/HCO3- antiporters |
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Term
When the intercalated cells are excreting H+ they are reabsorbing |
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Definition
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Term
If the pH of the tubular flui ddrops any lower than ____ , tubular secretion of H+ ceases for lack of a sufficient gradient |
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Definition
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Term
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Definition
When blood pH falls below 7.35 |
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Term
State of cells and CNS during acidosis |
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Definition
Cells are hyperpolarized, CNS depressed |
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Term
Can acidosis result in death? |
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Definition
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Term
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Definition
Confusion, coma, and disorientation |
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Term
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Definition
When ECF/Blood pH goes above 7.45 |
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Term
Status of nervous system during alkalosis |
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Definition
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Term
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Definition
Muscle spasms and respiratory paralysis |
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Term
In compensation, kidneys compensate for pH imbalances of what origin? |
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Definition
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Term
In compensation, respiratory system compensate for pH imbalances of what origin? |
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Definition
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Term
duration of respiratory compensation |
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Definition
can start in minutes and max out in hours |
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Term
duration of renal compensation |
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Definition
can begin in minutes but can take days to max out |
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Term
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Definition
The rate of alveolar ventilation fails to keep up with the body's rate of CO2 production |
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Term
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Definition
results from hyperventilation, in which CO2 is eliminated faster than produced |
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Term
What causes respiratory alkalosis |
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Definition
pulmonary disease or anxiety |
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Term
Causes of respiratory acidosis |
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Definition
Emphysema, pulmonary edema, respiratory center injuries, airway obstruction or injuries to muscles of respiration |
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Term
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Definition
Increased production of organic acids |
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Term
Causes of metabollic acidosis |
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Definition
Failure to excrete H+ in urine / Loss of bicarbonate due to diarrhea or renal dysfunction |
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Term
Examples of organic acids in acidosis |
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Definition
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Term
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Definition
State of Increased HCO3-, can result from overuse of bicarbonates such as oral antacids or IV bicarbonates or too much vomiting |
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