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Final
Human Physiology (Bios213) for final
128
Physiology
Undergraduate 2
05/03/2012

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Term
Which of the following can diffuse through a cell membrane?
Definition
fatty acid
Term
the amino acid sequence of a protein is referred to as its
Definition
primary structure
Term
primary active transport is directly involved in moving which of the following
Definition
co2 out of the lumen of the nephron
Term
where is the majority of water reabsorbed in the nephron
Definition
proximal convoluted tubule
Term
where is salt (NaCl) but not water reabsorbed in the nephron
Definition
ascending loop of henle
Term
where is water reabsorption in the nephron regulated by hormones and aquaporins
Definition
distal convoluted tubule/collecting duct
Term
which hormone regulates the reabsorption of potassium in the nephron
Definition
none of the above (aldosterone, anitdiuretic hormone, corticosteroids, na/k transportase)
Term
which of the following contributes significantly to the hypertonicity of the renal medulla which in turn is important in water reabsorption?
Definition
both a and b (na+ and urea)
Term
the capillary system within Bowman's capsule where blood is filtered is called
Definition
glomerulus
Term
shuttles are very important in moving molecules across membranes. a shuttle converts a molecule that cannot diffuse through a membrane into a compound that can. The original molecule is then regenerated on the other side of the membrane. Which of the following is an enzyme that plays an important role in a shuttle
Definition
carbonic anhydrase
Term
where does an action potential originate
Definition
axon hillock
Term
A positive ion found inside and outside a nerve cell has an ion equilibrium potential of 0. If all channels of an axonal membrane are open at the resting membrane potential, which direction will this ion move?
Definition
into the cell
Term
which channels are most important in causing depolarization?
Definition
voltage gated na+ channels
Term
which of the following produces an inhibitory postsynaptic potential
Definition
hyperpolarization
Term
a drug that specifically inhibited slow ca++ channels would primarily affect which of the following?
Definition
heartbeat
Term
which of the following will cause the greatest increase in the rate of action potential propagation along an axon
Definition
increased amount of myelination (and increased diameter)
Term
which of the following are characteristic of a nicotinic receptor
Definition
its found at the motor end plate
Term
which of the following is an example of 'referred pain'
Definition
angina pectoralis
Term
which of the following is the neurotransmitter specifically involved in sensing pain?
Definition
substance p
Term
which of the following is an important function of the sympathetic nervous system?
Definition
controls fight or flight response
Term
which of the following is true about the nervous and endocrine systems?
Definition
the response time is faster for the nervous system
Term
All the following are true about peptide hormones except
Definition
they enter the sell and bind DNA-- (they do typically act faster than steroid hormones, are often released in an inactive state, and are the most common type of hormone in the anterior pituitary)
Term
high concentrations of testosterone in males causes the development of female tissue. this effect of testosterone is called
Definition
pharmacological
Term
the MHC complex is involved in
Definition
recognition of self vs. non-self by the immune system
Term
LH causes an increased amount of estrogen to be produces in the ovary which, in turn, causes an increasing amount of LH to be released from the pituitary. This is called
Definition
positive feedback
Term
which of the following is not a steroid hormone
Definition
FSH or adrenaline(steroids often end in en/one)
Term
which of the following does not contribute significantly to type II diabetes?
Definition
autoimmune destruction of beta cells of pancreas
Term
all of the following are true about insulin except
Definition
it causes increased breakdown of glycogen and triglyceride
Term
which of the following is true about the innate immune response?
Definition
the response is to general rather than specific feature of pathogens
Term
which of the following are phagocytotic
Definition
macrophage
Term
which of the following produced antibodies
Definition
b-lymphocyte
Term
which cells must directly contact a pathogen to kill it?
Definition
a and c (t-cell and macrophage)
Term
all of the following are involved in inflammation except
Definition
dopamine
Term
which of the following in not an autoimmune disease
Definition
ALS (amyptropic lateral sclerosis)
Term
which proteins are found in thin filaments
Definition
actin, troponin, tropomyosin (all of the above)
Term
which of the following binds Na+ ions to initiate muscle contraction?
Definition
none
Term
excitation-contraction coupling involved all of the following except
Definition
twitch summation or pacemaker cells (does : t-tubule, action potential, terminal cisternae, ca++)
Term
which of the following occurs fastest?
Definition
typical action potential in a neuronal axon
Term
which of the following will cause the greatest increase in the force of whole-muscle contraction?
Definition
increasing the number of motor units recruited
Term
which of the following is true about moderate intensity exercise?
Definition
it occurs at 50% aerobic capacity and at the lactate threshold (b and c)
Term
exercise can
Definition
increase the number of sarcomeres and mitochondria
Term
which type of muscle can be stretched the greatest but still contract efficiently?
Definition
smooth muscle
Term
complement is necessary for
Definition
destruction of a pathogen by the immune system
Term
which parts of the heart are parts of the systemic circulation
Definition
right atrium, left ventricle
Term
what is the cause of the first heart sound
Definition
closing of the atrial venticular valves
Term
which ion channels are important in the spontaneous depolarization the threshold of pacemaker calls of the heart
Definition
voltage-gated Na+
Term
the cardiac action potential passes from the apex of the ventricles back up through the ventricles through modified myocardial cells called
Definition
Purkinje Fibers
Term
which wave on an EKG is due to depolarization of the atria
Definition
P
Term
which of the following are important components of inhibition of heart rate
Definition
vagus nerve, parasympathetic nervous system, and muscarinic receptor
Term
starings law of heart relates
Definition
force of contraction and end-diastolic volume
Term
congestive heart failure of the left ventricle
Definition
is treated with digitalis and results in pulmonary edema
Term
most co2 in blood is
Definition
in the form of bicarbonate
Term
your are reading an article about a new enzyme in sarcosome of a cell, this must be in what type of cell
Definition
muscle
Term
which of the following disorders are restrictive (due to decrease in vital capacity)
Definition
emphysema and pulmonary fibrosis
Term
which of the following is most important in inspiration
Definition
contraction of the diaphragm
Term
which of the following are true about hemoglobin
Definition
it is composed of 4 subunits. each bind an oxygen, and it binds carbon monoxide more tightly than oxygen
Term
a right-shifted oxygen dissociation curve
Definition
is found in adult hemoglobin in the presence of lactic acid
Term
which of the following are involved in the control of ventilation
Definition
all of the above : rhythm of breathing is controlled by pacemaker cells in medulla, peripheral chemoreceptors in the carotid and aortic bodies, chemoreceptors in the medulla
Term
which of the following are important in causing increased breathing during exercise
Definition
sensory nerves in muscles
Term
the nodes of ranvier plan an important role in
Definition
conduction of the nerve impulse
Term
the movement of glucose into the cell by facilitated diffusion
Definition
involves the finding of an ion such as Na+ to the transporter
Term
which of the following plays an important role in regulation of pH in body fluids/tissues?
Definition
all of above: amount of bicarbonate reabsorped, amount of H+ secreted, rate of ventilation
Term
what is the capillary network that surrounds nephron and helps maintain the high osmolarity in the medulla of the kidney
Definition
vasa recta
Term
which hormones regulate reabsorption of water or salt in the nephron
Definition
aldosterone and antidiuretic hormone
Term
water moves in and out of the nephron
Definition
by osmosis
Term
standard action potential is the axon of a neuron involves the movement of which of the following into the cell
Definition
sodium
Term
membrane potential from +50 to -70 is
Definition
repolarization
Term
muscarinic acetylcholine receptor has which component
Definition
g protein
Term
What is the most important factor that determines whether an excitatory or inhibitory potential is produced in a postsynaptic neuron?
Definition
the type of receptor
Term
which hormone is involved in the fight or flight response
Definition
epinephrine
Term
what is the main effect of glucagon
Definition
increases glucose level in the blood
Term
diabetes mellitus causes increased urine volume because
Definition
it increases tonicity of the urine
Term
which is true about the hormones of the posterior pituitary
Definition
they are peptides
Term
which of the following is structural muscle proteins of the sarcomere as opposed to regulatory muscle proteins
Definition
myosin
Term
which part of the myofiber allows the AP to travel deep into the interior of the myofiber
Definition
t-tubule
Term
which of the following is true about slow twitch muscle fibers
Definition
metabolism is mainly oxidative and they contain a lot of mitochondria
Term
high intensity exercise is fuels
Definition
primarily by carbohydrates
Term
true about glycolysis
Definition
involved the oxidation of glucose and occurs in the cytoplasm
Term
what is the main most general function of the Krebs cycle
Definition
to produced reduced cofactors
Term
which id the only major artery that caries deoxygenated blood
Definition
punmonary artery
Term
which of the following if true about pacemaker cells in the heart
Definition
they are regulated by the sympathetic nervous system, ther are regulated by the vagus nerve, they depolarize spontaneously
Term
cardiac action potential moves through the heart via
Definition
bundle of his and purkinje fibers
Term
which of the following are true about the cardiac cycle
Definition
all are incorrect (NOT- there is no blood in the ventricles before the artia contract, the right vent id thicker and contracts stronger, or blood is pumped out of the ventricles during the ventricule diastole)
Term
t wave of EKG
Definition
ventricular repolarization
Term
which of the following is true about cardiac arrhythmias
Definition
all: the most dangerous of these is ventricular fibrillation, they are often caused by ectopic pacemaker cells and they are diagnosed by aberrant patterns on ECG
Term
which of the following are true about cardiac output
Definition
it is increased by stimulation by the sympathetic nervous system
Term
which of the following contribute to venous return to the heart
Definition
all above: blood volume, skeletal muscle pump, contraction of the diaphragm
Term
accumulation of excess fluid in the body is
Definition
edema
Term
which is true about cholesterol
Definition
all: it is an essential component of biological membranes, is it the precursor of steroid sex hormones, it is call bad cholesterol when bound to low density lipoproteins not high density
Term
relative to normal hemoglobin a right shifted oxygen dissociation curve is observed in
Definition
normal hemoglobin in the presence of elevated co2 concentration
Term
which of the following are required conditions for natural selection to operated
Definition
exsistance of different phenotypes that are inherited
Term
which of the following are true about the evolution of lactose tolerance in humans
Definition
first evolved in northern europe
Term
which of the following is/are thought to result from parent-offspring conflict
Definition
preclampsia
Term
where is bicarbonate reabsorped in the nephron
Definition
proximal convoluted tubule
Term
which of the following are true about aldosterone
Definition
it regulates salt reabsorption
Term
which of the following are characteristics of hypovolemic shock
Definition
low blood pressure
Term
which of the following are physiological responses to correct blood acidosis
Definition
increased expiration of CO2 and increased secretion of h+
Term
which of the following passes through the cell membrane by secondary active transport
Definition
glucose out of the lumen of the nephron and into the nephron cell
Term
all of the following cells can have an action potential except
Definition
none-- all neuron, skeletal, and cardiac muscles can
Term
ion eq. potential at +50 which direction will positive ion move
Definition
into the cell
Term
which channel is most important with respect to causing a sustained action potential in the heat muscle
Definition
ca++ slow channel
Term
which of the following produces an excitatory postsynaptic potential
Definition
depolarization
Term
which of the following is important in physiological mechanisms of homeostasis
Definition
negative feedback and antagonistic paired processes
Term
which of the following are characteristics of a muscarinic receptor
Definition
all: it is hyperpolarizing, it is found in the vagus nerve, it is inhibitory, and it operates via a G-protein
Term
which of the following is true about edema
Definition
all: it often occurs due to congestive heart failure, drugs to combat it are diuretics and the most potent drugs inhibit reabsorption of Na+
Term
which of the following are important functions of the parasympathetic nervous system
Definition
inhibits heart rate and controls parastalsis in the intestines
Term
which of the following is the end result of beta oxidation
Definition
acetyl COA
Term
which of the following if an important difference between cardiac and skeletal muscle
Definition
cardiac muscle cells of the atria or ventricles are joined by gap junctions while cells of skeletal muscles are not
Term
which of the following directly causes lysis and destruction of an invading bacterial cells
Definition
t-cell
Term
which of the following components of the inflammatory response is produce in mast cells and increases permeability of blood cells
Definition
histamine
Term
which of the following is true about steroid hormones
Definition
they center the cell and bind to DNA
Term
WHich of the following is true about the Cori Cycle
Definition
it regenerates glucose from lactic acid produced in skeletal muscles
Term
Which proteins are found in the think filaments
Definition
myosin
Term
which of the following binds ca++ to initiate crossbridge formation in muscle cells
Definition
troponin
Term
which of the following is the key intermediate which links carbohydrate, lipid, and protein metabolism and which occurs in the mitochondrion
Definition
acetyl COA
Term
which of the following if true about passive immunity
Definition
all: no immunologial memory is involved, the person exhibiting immunity does not produce antibodies, immunity is short term
Term
which of the following is characteristic of diabetes mellitus not insipidtus
Definition
elevated glucose level in urine
Term
a left shifted oxygen dissociation curve
Definition
is found in fetal hemoglobin relative to adult hemoglobin
Term
carbonic anhydrase is important in which of the following
Definition
reabsorption of bicarb and production of bicarb in red blood cells
Term
injection of large amount of testosterone :
Definition
all: pharmacological effect, caused by conversion of testosterone into estrogen by aromatase and is caused by neg feedback of testosterone
Term
Penicillin is transporsted into the lumen of the nephrone in the proximate convoluted this process is called
Definition
secretion
Term
which of the following is important autrocrine/paracrine regulators
Definition
angiotensin
Term
The main cause of cyctic fibrosis is a malfunctioning
Definition
Cl- receptor
Term
The typical response of the kidney to tissue alkalosis
Definition
decreased reabsorption of bicarbonate
Term
which cell produces the myelin sheath of an axon
Definition
schwann cell
Term
Renal plasma clearance
Definition
is always less than the GFR
Term
Na+/K+ pumps
Definition
move Na+ out of the cell and K+ into the cell, are an example of active transport and are elcetrogenic
Term
when coltage across the membrane of a neuron becomes positive, this is referred to as
Definition
over shoot
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