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Final Study Guide
Final Study Guide
50
Pharmacology
Undergraduate 1
07/28/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
What is the roll of the immune system
Definition

The immune system protects the body from foreign invaders that would otherwise destroy it, or parts of it, via infection or cancer.

(pg 538)

Term
What is the first line of defense?
Definition
Nonspecific Defense Mechanisms (pg 539)
Term
What are our nonspecific defense mechanisms?
Definition
physical barriers, natural deterrents (fluids, or chemicals and innune cells that precent or attack invaders), and the inflammatory process
Term
What are the body's physical and anatomical barriers?
Definition
  • Mucus in the respiratory tract
  • Vertebral column, spinal cord fluid, and meninges
  • skin
Term
What are the natural physiological deterrents
Definition
  • Acidic secretions of the vagina
  • tears
  • lysozyme
  • nonspecifi immune system cells such as phago cytes and macrophages
Term
how does blood components act as a defense mechanism?
Definition
  • by clotting factors foun in the blood (platelets)
  • proteins aid in inflammation and release of phagocytes
Term
What is the second line of defense?
Definition
Specific Defense Mechanisms
Term
What is included in the specific defense mechanisms
Definition
antibodies and complements
Term
what do antibodies do
Definition
antibodies mark the invadins substance as a target
Term
what do the complements do
Definition
complements destroys the inavader
Term
What does it mean when the body is immunosuppressed
Definition
immunosuppressed means that the immune system is suppresed and its ability to fight infection
Term
Define Normal Flora
Definition
Normal flora consists of a group of microorganisms that occur naturally in the mouth, skin, and gastroitestinal (GI) tract
Term
What is the inflammation response
Definition
it is the response of the body to infection characterized by reddness, swelling, and heat in the localized area
Term
what is on the surface of antibodies
Definition
a combining site
Term
what attch to the combining site
Definition
the epitopes of the antigens
Term
what happens when the epitopes attach to the combining site
Definition
the antigen becomes disabled and created agglutinate. Then macrophages and phagoctes consume the disabled antigen
Term
what is the ability of the antibodies to disable a foreign invader called
Definition
humoral immunity
Term
What is a complement
Definition
a group of normall inactive enzymes that activate y the antibodies  and antigen attachment
Term
What do complements do one the antibody and antigen have binded
Definition
they attache to the two binding sites  and while the antibody is holding the antigen down the complement cells are drilling a hole in the cell which burst the cell.
Term
what is the basic cell structure
Definition
the cell membrane, cytoplasm, and DNA
Term
What is DNA
Definition
DNA is the genetic material that holds the blueprints of an organism
Term
What is RNA
Definition
It acts as a messenger to create protiens
Term
process from DNA to RNA to DNA
Definition

First DNA is unwound and an enzyme makes a copy of one of the strands

 

The copies strand is RNA, it is a attached to a ribosome which pulls in the protines necessary to match the protiens in the RNA and the recreate another DNA cell

Term
What is a pathogen
Definition
A pathogen is a disease causing organism
Term
what are the main routes of transmition of a pathogen or microbe
Definition

they are transmied via

  • dtouch 
  • contaminated bodily fluids
  • siliva 
  • air
  • food
  • water
  • insects
  • contaminated surfaces
Term
Antibacterials
Definition
Any medicine that is used for the treating of bacterial infections
Term
Antivirals
Definition
Used for viral infections
Term
Antifungals
Definition
Are used for fungal infections
Term
What are parasites
Definition
Parasites are any organism that depends on a host for survival
Term
What is Malaria
Definition
Malaria is a disease transmitted by parasites found in malaria -infected mosquitoes.
Term
Define Aerobic
Definition
Aerobic means that an organism requires oxygen to live
Term
What does Anaerobic mean
Definition
Anaerobic means that an organism doesn't require oxygen to live
Term
Define HIV
Definition
HIv is a human immunodeficiency virus
Term
How many stages are their to the invasion of HIV
Definition
there are 5 stages
Term
What is stage of of the HIV Virus
Definition
Stage 1- initial transmission and infection with HIV
Term
What is stage 2 of the HIV virus
Definition

Stage 2-infection without presentation of signs or symptoms (could last ten or more years)

 

Term
What is stage 3 of the HIV virus
Definition
Stage 3-signs and symptoms of HIV begin to appear
Term
What is stage 4 of the HIV virus
Definition
Stage 4-AIDS opportunistic infection begin; CD4 cell count or level at or below 200 per cubic milimeter of blood
Term
What is stage 5 of the HIV virus
Definition
Stage 5 final stage of wasting and infections; ends in death.
Term
what is the process of the HIV Virus invading the body
Definition

1. the HIV virus binds and fuses to the CD4 (white blood cell)

2. the HIV Virus tears a whole in the cell and enter the cytoplasm and breaks apart releasing its two Reverse Transcriptase enzymes and two RNA strands

3. The HIV RNA stands become binded together by the Reverse transcriptase enzyme in the cytomplasm creating an HIV DNA molecule

4. The new DNA enters the CD4 Nucleus and the integrase enyzyme insterts the new HIV DNA into the CD4 DNA creating a new HIV/CD4 DNA Hybrid. 

5. then the RNA polymerase and the hybrid DNA makes mRNA with atacted to the envelope protiens and viral proteins. This makes a cell full of poly peptides with the new viral information in it.

6. the protease enzyme breaks the polypeptides in the cell and makes more viral cells

Term
What is an autoimmune disorder
Definition
an autoimmune disorder is any disorder that causes your immune system to produce antibodies that attack your own tissues.
Term
what are the GENERAL treatments for autoimmune disorders
Definition
many times immunesuppressents which helps to keep their body from getting attacked by its own cells but it also makes the highly suseptable to other infectious diseases
Term
What is drug resistant
Definition
drug resistant is when any organism is able to still function properly in the prescent of the drugs that was ment to combat it
Term
what is a pcn
Definition
PCNs are penecillens
Term
True or Flase: PCNs are divided into four groups of varying spectruf of activity
Definition
True
Term
How many generations are there of PCNs
Definition
Four
Term
Name the four generations of PCNs
Definition
Natural PCNs, penicillinase-resistant  PCNs, amino PCNs, and exended-spectrum PCNs
Term
what percent chance does someone who is allergic to PCNs have to be allergic to Cephlasporins
Definition
5-20 percent chance
Term
How many groups are there of cephlasporins
Definition
four
Term
how ar the four groups of cephlesporins catagorized
Definition
by their antimicrobial properties
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