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Like illustrations, tables, video
Think in pictures
Notice expressions, gestures, body language |
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Traditional lectures are helpful
Material is clearer after hearing it
Listen to tone, speed, and mannerism |
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Enjoy hands on learning activities
Fidget or doodle during lecture
Like to be physical while learning |
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- Observing
- Proposing Ideas
- Testing
- Discarding those ideas that fail
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Proposed explaination
- Testable and potentially falsifiable
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Powerful, broad explaination
Rests on many hypotheses that have been tested |
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Combining a series of specific observations into a generalization |
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factors that can change in value under different conditions |
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A factor that can be manipulated/change
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A factor that cannot be changed
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all organisms are composed of cells
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fundamental forms of matter |
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the smallest units of an element
- composed of protons, neutrons, electrons
- Electron: negative charge
- Protons: positive charge
- Neutrons: neutral charge
Location
Electron are outside the nucleus
Protons/Neutron within the nucleus
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But all living organism
- Grow and develop
- Reproduce
- Utilize energy-metabolism
- Respond to the environment
- Maintain homeostasis
- Evolve
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Unregulated cell division
- divide when they shouldnt
- invade surrounding tissues
- move to other locations in the body
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An organized profile of an individual's chromosomes. Chromosomes are arranged and numbered by size, from largest to smallest
Autosome: non-sex chromosomes [twenty-two chromosome]
Sex Chromosome: X or Y chromosome [twenty-third chromosome]
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One molecule of DNA is wrapped around proteins to a form a structure containing hundreds of genes
- Chromosome are uncondensed before cell division
- Duplicated chromosome, held together at the centromere: sister chromatids
[image]
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Homologous Pair of Chromosomones |
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Definition
contains the same gene
Different version of the gene: allele
- Same function
- Different DNA sequence
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Haploid vs. Diploid Cell States |
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Definition
Haploid
- gamete
- one set of chromosome (n)
- created-Meiosis
Diploid
- somatic cells
- two set of chromosome (2n)
- zygote; egg/sperm cells
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Definition
separates the members of homologous pairs
- Resulting cells are haploid
Stages of Meiosis
Interphase
DNA replication
Prophase
DNA condense into chromosome
Crossing over
Nuclear Envelope disappear
Metaphase
Homologous pair align at the center
Random alignment
Anaphase
Homologous pairs are separated
Telophase
Two daughter cells-produced
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Definition
Separates the sister chromatids
- Produce genetically unique haploid cells
Stages of Meiosis
Prophase
Nuclear envelope disappears
Metaphase
Chromosome align at the center
Anaphase
Sister Chromatids are separated
Telophase
Four haploid daughter cells result
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Definition
Exchange of equivalent portions of chromosomes between members of a homologous pairs
- Results in new types of gametes being formed
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The way in which different pairs of chromosomes align and get separated during meiosis I-random
- Results in different types of gametes being formed
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Produces genetically identical daughter cells
- Separates sister chromatids
Stages of Mitosis
Prophase
Nuclear Envelope disappears
Microtubules pull the chromosome toward the middle
Prometaphase
Proteins attach to the centromeres creating the kinetochores
Metaphase
Chromosome are aligned across the metaphase plate
Anaphase
Sister Chromatids separates
Telophase
Nuclear envelopes reform around chromosomes
Chromosomes revert to uncondensed form
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Failure of homologous to separate normally during meiosis
- Results in a gamete having too many chromosomes-trisomy or one too few chromosomes-monosomy
Ex: Down-syndrome; Turner Syndrome
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Creations of gametes, which are combined from two parents
- Offspring are genetically different from one another and from the parents
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- Mother's egg and father's sperm each contain half of the information to build a human
- This single cell contains all the information on how to build the human
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Description of the alleles for a particular gene in an individual
Types:
- Homozygous
- Heterozygous
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Physical traits of an individual |
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both alleles for a gene are identical |
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the gene has two different alleles |
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the phenotype of an allele is seen only when homozygous |
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the phenotype is seen when homozygous or heterozygous |
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Punnet Square/Probability
Curly hair is recessive; straight hair is dominant. A heterozygous woman with curly hair marries a men, who is a homozygous dominant character for straight hair. Predict the outcome-children
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Fifty-Fifty chance--the offspring will have either straight or curly |
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Carriers of these disease--Heterozygotes
A recessive human genetic disease
A dominant human genetic disease
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Show continuous variation of large range of phenotypes
Heritability
Proportion of the variation within a population due to genetics difference among individuals
Polygenic Traits
Results of several genes
Each with more than one allele |
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Definition
Are located on the X chromosome |
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Definition
- When an X-bearing sperm fertilizes the egg cell, a female results
- When a Y-bearing sperm fertilizes, an male results
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When a string of RNA is wrapped around the chromosome
- Guarantees that all females actually receive only one dose of the proteins produced by genes on the X chromosome
- Occurs in all of the cells of a developing female embryo; about the time that embryo implants in the uterus
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The process of using instructions carried on a gene to create proteins |
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Definition
- Double-stranded
- Each nucleotide composed of deoxyribose, phosphate, and nitrogenous base
Bases:
- Adenine
- Thymine
- Guanine
- Cytosine
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Term
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Definition
- Single-stranded
- Nucleotides comprised of ribose, phosphate and nitrogenous base
Bases:
- Adenine
- Guanine
- Thymine
- Cytosine
- Uracil-pair with adenine
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Steps of Protein Synthesis |
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Definition
Transcription
- located in the Nucleus
- DNA-->RNA
- produce RNA
RNA Process
- located in the RNA polymerase
- RNA-->mRNA
- produce mRNA
Translation
- located in the Cytoplasm
- mRNA-->tRNA
- produce amino acid
Protein Process
- located in the Rough Er
- amino acids-->protein
- produce protein
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Definition
Codon
Sequence of mRNA to code for a specific amino acid
Anticodon
Sequence of tRNA to match with the codon |
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Definition
Change in genetic sequence
- Changes in genetic sequence might affect the order of amino acids in a protein
- Protein function-dependent on the precise order of amino acids
Possible Outcomes:
- No change in protein/Neutral Mutation
- Non-functional protein
- Different protein
Types of Mutation:
Base-Substitution
Simple substitution of one base for another
Frameshift
addition/deletion of a base
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