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final review
bugs and drugs 2
31
Science
Undergraduate 2
04/20/2007

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Term
May cause tendonitis or tendon rupture.
Definition
Fluoroquinolones
Term
DNA synthesis inhibitor that has DI with Al, Mg, Fe, Zn, CA.
Definition
Fluoroquinolones
Term
Fluoroquinolone used for anthrax
Definition
ciprofloxacin
Term
Only Fluoroquinolone that covers some gram +
Definition
Ofloxacin
Term
DOC for PCP and HIV
Definition
Trimethoprim/sulfamethoxazole
Term
Only Fluoroquinolone that covers anaerobes
Definition
Moxifloxacin
Term
two fluoroquinolones that have adr of QTc prolongation.
Definition
Moxifloxacin and Gemifloxacin
Term
Spectrum of Metronidazole
Definition
Only Anaerobes
Term
DOC for Clostridium difficile
Definition
Metronidazole
Term
Is trimethoprim-sulfamethoxazole ok to give to preg. women?
Definition
NO! Don't use if their breast feeding or in children either.
Term
Causes brown discoloration of urine.
Definition
Nitrofurantoin
Term
Be aware of CrCl when using which drugs?
Definition
Nitrofurantoin, Amphotericin
Term
Used for HSV one and two, shingles, and chickenpox.
Definition
Acyclovir
Term
ADR of Penciclovir?
Definition
local mild erythema
Term
Indicated for recurrent herpes labialis
Definition
Docosanol
Term
Spectrum of Amantadine/Rimantadine
Definition
Influenza type A
Term
Has a spectrum of Influenza A & B and avian flue
Definition
Oseltamivir
Term
Your patient has pre-existing lung conditions but needs drug for influenza A. Which drug should he stay away from? Why?
Definition
Zanamivir; may cause bronchospasm and respiratory decline
Term
What is the preferred dosing for interferon alpha?
Definition
long acting- once weekly (SQ)
Term
Which drug that is used in combo with interferon alpha may cause hemolytic anemia or major birth defects? What is is used to tx?
Definition
Ribavirin; Hep C
Term
Treats HIV and HBV and may cause acute exacerbation with discontinuation of medication
Definition
Lamivudine or Entecavir (Entecavir is used if resistent to Lamivudine)
Term
Used for chronic hep B
Definition
Adefovir
Term
Which individual azole should your patient stay away from if he has heart problems?
Definition
Itraconazole
Term
Individual azole that can administered topically
Definition
Ketoconazole
Term
Azole that is commonly used for yeast infections.
Definition
Fluconazole
Term
Azole that may cause visual disturbances.
Definition
Voriconazole
Term
True or false. Amphotericin may cause hyperkalemia.
Definition
False, it may cause HYPOKalemia
Term
Drug of choice for many systemic fungal infections?
Definition
Amphotericin
Term
Used in Aspergillosis and systemic candida infection
Definition
Caspofungin
Term
Indicated for onychomycosis (oral), tinea corporis, tinea cruris, tinea pedis (topical)
Definition
Terbinafine
Term
Active only against trichophyton rubrum
Definition
Ciclopirox
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