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final review
antihistamines/colds/copd/etc.
35
Science
Undergraduate 3
04/20/2007

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Cards

Term
Activation of H1 receptors causes what in the blood vessels and what in the lungs?
Definition
Vasodilation
Bronchoconstriction
Term
Are first generation antihistamines sedating or not sedating?
Definition
Sedating
Term
Which antihistamine is used both in insominia and motion sickness?
Definition
Diphenhydramine
Term
What is the largest drug interaction with antihistamines?
Definition
Alcohol; other CNS depressants are no good either, like benzodiazepines and opiods
Term
Is dephenhydramine first or second generation antihistamine?
Definition
first
Term
Which antihistamine can you give oral, IV, IM, or rectally?
Definition
Promethazine
Term
Which second generation antihistamine agent is given through a nasal spray or opthalmicly?
Definition
Azelastine
Term
DOC for seasonal or perennial rhinitis?
Definition
Intranasal glucocorticoids
Term
Phenylephrine (Sudafed) and Pseudoephedrine are what kind of drugs?
Definition
Decongestants
Term
Which drug used for allergic rhinitis may cause rebound congestion?
Definition
Decongestants
Term
Your patient has CAD and HTN but you want to treat his allergy based rhinitis. Which drug should you stay away from?
Definition
Decongestants
Term
T or F. Topical decongestants should not be used for more than 3 days.
Definition
Oh Yeah
Term
T or F. Decongestant drops are preferred for children rather than other routes.
Definition
yep
Term
Which route when using decongestants will give the most ADR's of systemic effects.
Definition
Oral
Term
Most effective cough suppressant.
Definition
Codeine
Term
Which non-opiod antitussive will cause paralysis of the mouth and pharynx if chewed, crushed, or sucked on?
Definition
Benzonatate
Term
Your patient has asthma or COPD but needs a protussive, which one should he stay away from?
Definition
Guaifenasin
Term
Which mucolytic agent smells like rotten eggs?
Definition
Acetylcysteine
Term
Your patient has frequent night time symptoms of asthma. What classification does this fall under?
Definition
Severe Persistent
Term
What is the therapy for your patient with moderate persistent asthma?
Definition
low dose inhaled glucocorticoid and long-acting beta2 agonist
Term
Which stage of asthma could you use cromolyn as an alternative therapy?
Definition
Mild persistent
Term
Which drugs are the initial therapy for exacerbations of asthma?
Definition
beta 2 agonists
Term
What is the mainstay of therapy for exercised induced asthma?
Definition
Inhaled short acting beta 2 agonists
Term
Is Albuterol a short or long-acting beta adrenergic agonist?
Definition
Short
Term
Name two long acting inhaled beta adrenergic agonists.
Definition
Formoterol and Salmeterol
Term
What is the MOA of glucocorticoids?
Definition
Suppress inflammation to decrease asthma symptoms
Term
What is the first therapy for moderate-severe asthma?
Definition
glucocorticoids
Term
What should you do to prevent oropharyngeal candidiasis and dystonia when taking glucocorticoids?
Definition
Gargle after each administration
Term
Are oral glucocortoids like prednisone more of a first line therapy or reserved for only severe asthma?
Definition
Use only when symptoms can't be controlled. ADR are horrendous for oral gluces- bad adrenals, bad bones, too high blood sugar, ulcers, bad growth in kids
Term
Which leukotriene modifier should not be given with food?
Definition
Zafirlukast
Term
Which Leukotriene modifier is used for asthma and allergic rhinitis?
Definition
Montelukast
Term
Which two out of the three leukotrine modifiers could cause Churg-Strauss syndrome?
Definition
Zafirlukast and Montelukast
Term
How would you treat someone at risk for COPD?
Definition
Influenza and Pneumoccocal vaccine
Term
Tx for stage 3 (severe) COPD?
Definition
short acting bronchodilator, long acting bronchodilator, and inhaled glucocorticoid
Term
anticholinergic drug that has metallic taste as adr and avoided in ppl with peanut allergy
Definition
Ipatropium
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