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Final Quiz - Antibiotics & Mode of Action
Final Quiz - Antibiotics & Mode of Action
16
Microbiology
Undergraduate 2
05/09/2012

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Term

pennicillins

carbapenems

cephalosporins

Definition
cell wall inhibition - stops production of peptidoglycan
Term
vancomycin
Definition
polypeptide antibiotic - cell wall inhibition - stops production of peptidoglycan - used to treat MRSA
Term
isoniazid (INH) in combo with rifampin & ethambutol
Definition
antimycobacterial, used to treat TB
Term
chloramphenicol
Definition
protein synthesis inhibition - binds to 50S sub-unit and inhibits formation of peptide bonds
Term
streptomycin
Definition
protein syntesis inhibition - changes the shape of the 30S portion causing the code on mRNA to be read incorrectly
Term
gentamicin
Definition
kills Pseudomonas - protein syntesis inhibition - changes the shape of the 30S portion causing the code on mRNA to be read incorrectly
Term
tetracyclines
Definition
bind to the 30S sub-unit and prevent attachment of tRNA to mRNA
Term
cyclohexamide
Definition
-kills eukaryotic parasites by protein synthesis inhibitor - bonds to the 60S subunit and prevents polypeptide enongation
Term
rifampin
Definition
-nucleic acid inhibitor, used to treat TB
Term
trimethoprim/sulfamethoxzole (TMP-SMZ)
Definition

competitive inhibitors of essential metabolies

two durgs are synergists , work at much lower dose than if each used alone

Term
Amphotericin B
Definition
antifungal - toxic to kidneys
Term
nystatin
Definition
antifungal - used topically to treat Candida albicans
Term
interferons
Definition
antiviral, inhibit DNA or RNA synthesis, inhibit spread of virus to new cells
Term
chloroquine
Definition
antiprotozoan - antimalarial
Term
metronidazole (Flagyl)
Definition
antiprotozoan, for giardia & trichomonas
Term
ivermectin
Definition
antihelminthic drug
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