Shared Flashcard Set

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Final for 153
Final exam
78
Pharmacology
Undergraduate 1
12/09/2009

Additional Pharmacology Flashcards

 


 

Cards

Term
What is another name for a medication that is naturally occurring and has been chemically modified?
Definition
SEMISYNTHETIC DRUGS
Term
Which law regulates the administration of anabolic steroids? 
Definition
CONTROLLED SUBSTANCES ACT
Term
Which organization is responsible for approving new drugs in the United States
Definition
FOOD & DRUG ADMINISTRATION
Term
Which site of drug absorption has the largest surface area?
Definition
SMALL INTESTINE-LARGE SURFACE AREA FOR ABSORPTION
Term
Protein binding has which effects on drug action?
Definition
PROTEIN BINDING ALLOWS PART OF A DRUG DOSE TO BE STORED & RELEASED AS NEEDED.
Term
Define serum half-life of medication.
Definition

 

CALLED ELIMINATION HALF-LIFE, IS THE TIME REQUIRED FOR THE SERUM CONCENTRATION OF A DRUG TO DECREASE BY 50%

Term
The physician orders potassium chloride 25 mEq to be added to the patient's IV solution. The vial reads 10 mEq/5 milliliters. How many milliliters will be added to the IV solution?
Definition
12.5 mL
Term
What is the most appropriate action taken by the nurse if a patient has a gastrostomy tube, and the pharmacy has delivered an extended-release tablet
Definition
Reorder the medication; emptying a capsule to give the medication orally or Gi tube administers an overdose with potentially serious adverse effect or death.
Term
When administering NPH insulin which action is it imperative to perform to the bottle prior to administration?(hint think mixing)
Definition
Liquid must be rotated rubbed in hand gentle before measuring dose make sure it is cloudy
Term
Define the nursing process?
Definition
Systemic way of gathering and using info. To plan and provide individualized patient care and to evaluate the outcomes of care
Term
What are the major component of a critical pathway?
Definition

Medical Diagnosis

Aspects of care related to the medical diagnosis

Desired patient outcomes

Time Frames (usually days) to achieve the desired outcomes during the expected length of stay

 

Term
What type of analysis is known as the rigorous analysis, comparison, and summarization of randomized drug trials?
Definition
Meta-analysis
Term
What is an important nursing intervention prior to and during administering Morphine? (hint not just assessing for pain).
Definition
Check respiration
Term
Drug of choice to treat respiratory depression in opiod use? (hint reversal agent for narcotics)
Definition
Opioid antagonist Naloxone (Narcan
Term
The most effective way to evaluate pain and the response to analgesics?
Definition

Pain scale

Term
What is an important assessment in a patient taking motrin that presents to the hospital with abdominal pain?
Definition
Bleeding
Term
What is a common adverse effect of acute or chronic Tylenol overdose?
Definition
Hepatotoxicity
Term
Antidote for Tylenol poising?
Definition
Mucomyst
Term
What is the advantage of acarbose?
Definition
In the GI tract & thereby delay digestion of complex carbohydrates into glucose & other simple sugar
Term
What is the possible cause of pain in hands and feet of a diabetic patient?
Definition
Neuropathy
Term
What is the type of insulin that can be administered IV?
Definition

Regular insulin

Term
What type of yeast can normally be present in the vagina and intestinal tract?
Definition
Candida Albicans
Term
What type of infection is likely to occur in a burn patient, cancer patient, or HIV patient? (compromised immune system creating an opportunity for the infection)
Definition
Opportunistic infection
Term
What type of infection occurs in patients in hospitals or other health care facilities?
Definition
Nasocomial Infections
Term
Medication administered as prophylaxis for rheumatic fever?
Definition
Penicillin
Term
What type of anti-infective is Unasyn?
Definition
Penicillin beta-lactamase inhibitor combination
Term
Drug of choice to treat B. fragilis?
Definition
Cefoxitin (Mefoxin)/ Meropenem (merrem)
Term
What type of anti-infective agent is effective against Pseudomonas?
Definition
Tobramycin
Term
What aminoglycoside is used in 4- to 6- treatment regimen for tuberculosis?
Definition
Streptomycin
Term
What is an advantage of a fluoroquinolone over an aminoglycoside?
Definition
Fluoroquinolone has a broader spectrum Fights gram positive and gram negative bacteria. Well absorbed in GI
Term
What is the purpose of prescribing Pyridum for urinary tract symptoms?
Definition

Decrease pain

Turn urine orange red

Term
What type of sulfonamide is administered for burns and how is it administered?
Definition

Topical Sulfonamides Mafenide (Sylfanylon)

Topical application to burned area, once/twice daily in a thin layer

Term
Can you administer tetracycline to children under 8? Why or why not?
Definition

No, affect their teeth and bone

Term
What blood levels should be monitored with Ketek
Definition
Liver function
Term
How is chloramphenicol eliminated from the body?
Definition

Metabolism in the liver and

 Excreted in the urine

Term
Drug of choice for traveler’s diarrhea?
Definition
Rifaximin (Xifaxan)
Term
What is the expected outcome for treatment with Zovirax?
Definition

Decrease viral shedding and duration of skin lesions and pain

Term
What patient teaching should be given for Crixivan in regards to fluid intake?
Definition
To avoid nephrolitiasis- consume 48-64 oz. of water and other fluid daily.
Term
What is the action of amphotericin B?
Definition

Binds with ergosterol and disrupts cell membrane

Term
What is the length of treatment with the above medication used for severe fungal infections?
Definition
4 to 12 weeks
Term
What is the advantage of Abelcet over amphotericin B?
Definition

Higher concentration in disease tissue than than amphotericin B decreased adverse effect is used in client renal impairment

Term
How long does it take for Giardia infections to occur after ingestion of the cysts?
Definition

1-2 weeks

Term
What medication should be administered to prevent the development of malaria?
Definition
Chloroquine phosphate
Term
What medication should be administered with chloroquine for the treatment of extratestinal amebiasis?
Definition
Metronidazole (Flagyl)
Term
How do inhaled corticosteroid agents assist in the treatment of asthma?
Definition
Inhaled corticosteroid agents suppress the release of inflammatory mediators, block the generations of cytokines, and decrease the recruitment of airway eosinophils.
Term
What is the first line therapy for relief of an acute asthma attack?
Definition
Administer a Beta2-adrenergic agonist
Term
What foods should be avoided in the patient taking theophylline?
Definition

Chocolate

Term
How does an allergic reaction affect the body and lungs?
Definition
An allergic reaction produces contraction of the smooth muscle in the bronchi & bronchioles this stimulation of vagus nerve ending this stimulation of vagus nerve ending which increased mucous gland producing nasal congestion.
Term
What type of hypersensitivity reaction causes allergic rhinitis?
Definition
Type 1 response
Term
What medication type will assist in preventing a reaction of a packed red blood cell transfusion?
Definition
Premedication with an antihistamine
Term
What type of microorganism causes the common cold?
Definition
Virus
Term
What disease processes are contraindicated in the use of Afrin?
Definition
Afrin (oxymetazoline) is contraindicated in patients with sever hypertension or coronary artery
Term
Signs and symptoms of Congestive Heart Failure?
Definition
The manifestation of CHF are dyspnea and fatigue which can lead to exercise intolerance and fluid retention resulting in pulmonary congestion and peripheral edema. Clients with compensated (asyptomatic) CHF usually have no symptoms at rest and no edema dyspnea and fatigue occur only with activities involving moderate or higher levels of exertion.
Term
Therapeutic level for digoxin?
Definition
0.5-2.0 mg/ml
Term
What is the antagonist/antidote for dig toxicity?
Definition
Digibind (dogoxin immune Fab)
Term
How is hypertension defined?
Definition
Hypertension is usually defined as a systolic pressure above 140 and diastolic pressure above 90
Term
A patient is taking capoten what electrolyte imbalance might they be prone to?
Definition
Potassium
Term
What electrolyte imbalance might a patient taking a Potassium-sparring antidiuretic be prone to develop?
Definition
Hyperkalemia
Term
What diuretic is administered is for a patient with increased intracranial pressure?
Definition
Osmotic diuretics
Term
When treating patients with edema what is the recommended weight loss per day?
Definition
Approximately 2lbs. 1 kg per day
Term
What is the normal potassium serum level?
Definition
3.5-5.0 mEq/L
Term
What is a main adverse effect of Coumadin?
Definition
Bleeding
Term
Why is LMWH used versus heparin?
Definition

 

Prevention management thromboembolic during surgery, has less thrombocytopenia then herpin

Term
What lab values monitor Coumadin therapy?
Definition
PT/INR
Term
Why is bismuth added to the medication regimen of someone with H. pylori complicated peptic ulcer disease?
Definition
A bismuth preparation is added to some regimens. Bismuth exerts antibacterial effects against H. Pylori by disrupting bacterial cell walls, preventing the organism from adhering to the gastric epithelium, and inhibiting bacterial enzymatic and proteolytic activity.
Term
What risk is decreased when using ranitidine over cimetidine?
Definition
Cause drug interactions
Term
How long does it take for the effects of a proton pump inhibitor used t treat to erosive gastritis?
Definition
1-2 weeks
Term
Which laxative is most likely prescribed the night before a patient is scheduled for a colonoscopy?
Definition
Polyethylene glycol-electrolyte solution under saline laxatives
Term
Which laxative is administered to lower serum ammonia levels?
Definition
Lacunose
Term
Which laxative is most likely administered in a child with an iron overdose?
Definition
Polyethylene glycol-electrolyte solution (NuLYTELY)
Term
Which antiemetic is commonly used to treat nausea and vomiting in radiation therapy patients?
Definition
Prochlorperazine (Compazine)
Term
What is the antiemetic administered as a last defense in hyperemesis gravidarum?
Definition
Phenothiazines
Term
What is the antiemetic of choice for children?
Definition

Promethazine

Term

Solve the following ratio & proportion problem

5:100=X:1000

X=

Definition
 X= 50
Term

Multiply the following decimals (round to the nearest tenth)

0.64 x 0.8

Definition
0.5
Term

Convert the following traditional time to military time

6:15

Definition

0615 am

1815 pm

Term

ordered Biaxin 1000mg, po q 8 h

available Biaxin 250mg

How many tabs would you administer every 8 hours

Definition

4

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