Term
| In the PNS, when a neuron undergoes ______, the axon is deprived of essential proteins that are only synthesized in the soma |
|
Definition
|
|
Term
| In an axotomy, the distal end of the axon & its myelin sheath quickly degenerate in a process known as ______ |
|
Definition
| Wallerian (anterograde) degeneration |
|
|
Term
| In anterograde degeneration, tissue ______ clear the degenerating material |
|
Definition
|
|
Term
| In an axotomy, ______ cells will remain in the damaged area & undergo mitosis & proliferation promoted by macrophages |
|
Definition
|
|
Term
| The ______ cells will form a column that connects the cut end of the axon with the original target |
|
Definition
|
|
Term
| The Schwann cell column is important for guiding a regenerating ______ back to its appropriate target |
|
Definition
|
|
Term
| The proximal end of an axon will die back by ______, depending on the damage |
|
Definition
|
|
Term
| In early stages of regeneration, the cell will exhibit ______ & ______ |
|
Definition
| chromatolysis & eccentric relocation of the nucleus |
|
|
Term
| Axon terminals that innervate the soma & dendrites retract their synpases by ______ |
|
Definition
|
|
Term
| Upon successfully reaching the target, regenerated axons will undergo ______ |
|
Definition
|
|
Term
| Healthy axons near degenerating fibers develop ______ that grow to the abandoned synaptic sites |
|
Definition
|
|
Term
| Axotomy removes a retrogradedly transported _______ signal derived from the target |
|
Definition
|
|
Term
| The best characterized neurotrophic signal is ______ |
|
Definition
|
|
Term
| Unlike PNS Schwann cells, ______ in the CNS synthesize glycoproteins that suppress axon growth |
|
Definition
|
|
Term
| The best known myelin-associated growth inhibitors is ______ |
|
Definition
|
|
Term
| Axons of retinal ganglion cells will not grow through a resected ______ |
|
Definition
|
|
Term
| The axons of retinal ganglion cells will regenerate through a ______ from a peripheral nerve graft |
|
Definition
|
|
Term
| Failure to show regeneration in the CNS is a property of the _______ & not the neurons |
|
Definition
|
|
Term
| Growth is more likely to be greater in gray matter than in white, given the lower levels of _______ in the former |
|
Definition
|
|
Term
| Greater recovery of function is achieved by blocking the actions of ______ |
|
Definition
|
|
Term
| Recovery of function is improved by injection of ______ from the olfactory nerve |
|
Definition
| olfactory ensheathing cells |
|
|
Term
| Neurogenesis is especially well established in the ______, where newly generated neurons can make functional connections with CA3 cells located nearby |
|
Definition
|
|
Term
| The DG serves in ______ for discriminating events both spatially & temporally |
|
Definition
|
|
Term
| CNS neurons are capable of considerable ______ plasticity throughout life |
|
Definition
|
|
Term
| Occasional spontaneous cell loss is followed by _______ & ______ from surviving local axons |
|
Definition
| collateral sprouting & reactive synaptogenesis |
|
|
Term
| _______ are modifiable by experience |
|
Definition
|
|
Term
| ______ accounts for early reorganization, implying that weak connections exist that are not readily apparent in physiological recordings |
|
Definition
|
|
Term
| _______ contributes to long-term reorganization of the nervous system, particularly after injury |
|
Definition
|
|
Term
| In ______, patients who have lost a hand experience cortical expansion of the intact afferent pathways that normally terminate in areas surrounding the hand representation |
|
Definition
|
|
