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Female Repro Path 3
PP3
79
Veterinary Medicine
Professional
08/22/2016

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Term
In general, what are some infectious causes of aboriton?
Definition
-bacteria, viruses, fungi, protozoa
Term
In general, what are some non-infectious causes of abortion?>
Definition
-toxic, iatrogenci (hormonal), vascular accident/trauma
Term
When during pregnancy do most abortions occur?
Definition
-third trimester
Term
What are some abortion lesions seen on the placenta?
Definition
-edema
-discolortaionsL necrosis, inflamm, hem, etc
Term
What are some fetal lesions seen due to aboriton?
Definition
-autolysis, septicemia, brain malformations, anasarca
Term
What are some abortion lesiosn seen in the dam?
Definition
-metritis, weight loss, etc
Term
What are some sequelae of retained fetal membranes?
Definition
-edometirits, septicemia, DIC
Term
What are some of the causes of retained fetal membranes?
Definition
-infectious, nutritional, hormonal, circulatory, hereditary, environmental, but usually multifactorial
Term
What is the most common non-infectious cause of abortion in the mare?
Definition
-twinnin: growth retardation and placental insufficiency cuases 80% to abort mid-gestation
Term
What is the most important cuase of abortion in the mare?
Definition
-premature placental separation
Term
What is the common name for premature placental separation?
Definition
-red bag delivery
Term
What is the second most common non-infectious cause of equine abortion in US?
Definition
-umbilical cord torsion
Term
How long is a normal equine Thoroughbred umbilical cord?
Definition
-<75 cm long
Term
In which species does adventitial placentation occur?
Definition
-cattle
Term
What is the clinical significance of hippomanes?
Definition
-none
Term
Describe mummification.
Definition
-cervix closed and environment sterile
-mare durin gtwin pregnancy
-sow subsequent to parvovirus infection
Term
What is fetal maceration?
Definition
-fetal digestion
Term
When does fetal maceration occur?
Definition
-when bacteria is present
Term
What are the 9 important cuases of cattle abortions?
Definition
-BVDV, leptospirosis, brucellosis, neospora, IBR (BHV-1), mycotic, A. pyogenes, sporadic bacteria, trichomonas
Term
What are the 5 important causes of infectious sheep/goat abortions?
Definition
-coxiella burnetii, campylobacter, chlamydophila, toxoplasmosis, leptospirosis
Term
What are the 7 important causes of infectious equine abortion?
Definition
-EHV-1, EVA, mycotic, Strep equi zooepidemicus, Staph, E coli, MRLS (Mare Repro Loss Syndrome)
Term
What are the 4 important causes of infectious swine abortion?
Definition
-PRRSV, Parvovirus, Leptospirosis, Pseudorabies
Term
What is the important cause of infectious canine aboriton?
Definition
-herpesvirus
Term
What is the Campylobacter sp. in cattle?
Definition
-C. fetus var venerealis
Term
What are the lesions seen in cattle due to Campylobacter sp?
Definition
-chorioallantosi edema: cotyledon necrosis
Term
When during pregnancy does abortion due to Campylobacter sp in cattle occur?
Definition
-mid tem
Term
What Campylobacter species cause abortion in sheep and goats?
Definition
-C fetus fetus and C. jejuni
Term
What lesions do we see on sheep/goat fetus due to Campylobacter spp?
Definition
-necrotizing hepatitis
Term
What lesions do we see on the dam ddue to Campylobacter spp in sheep and goats? Is only one animal affected?
Definition
-intercotyledonary edema and friable cotyledons
-abortion outbreaks
Term
Describe the lesions seen on the dam dur to Brucella abortus in cattle. In the fetus?
Definition
-Dam: IC edema (leathery) cotyedon necrosis
-Fetus: cavitary effusionn/ pneumonia
Term
How is Brucella canis transmitted?
Definition
-venereal or ingestion transmission
Term
What lesions do you see in the dam with Brucella canis? What about the fetus?
Definition
-Dam: placentitis, lymphadenitis
-Fetus: dendocarditis, pneumonia, kidney, hemorrhage, hepatitis
Term
What lesions do you see in the dam with B. ovis in sheep? What about in the fetus?
Definition
-DAm: epididymitis and placentitis
-Fetus: pneumonia, nephritis, etc
Term
Where do you see B. melitensis in sheep and goats geographically?
Definition
-Mediterranean, Latin America
Term
What is important about B. melitensis?
Definition
-CDC Category B bioterrorist agent
-zoonotic through cheeses
Term
When during pregnancy does abortion occur due to B. melitensis?
Definition
-third trimester
Term
What lesions occur in pigs due to Brucella suis in addition to abortion?
Definition
-mucopurulent exidate and miliary (granulomatous endometritis) in the uterus
-also get infection in bones and joints
Term
What is the reservoir of Brucella suis in the USA? Is it zoonotic?
Definition
-feral swine
-yes
Term
What is the agent of Coxiella burnetii? Describe the affected species?
Definition
-Coxiella burnetii
-goats >> sheep > cattle
Term
HOw is Q fever transmitted? Is it zoonotic?
Definition
-ingestion or inhalation
-yes
Term
What placental lesions are seen due to Q fever?
Definition
-leathery placenta
Term
What is the name for disease resulting frm Chlamydophila abortus?
Definition
-enzootic ovine abotion
Term
Describe the herdwide consequences of Chlamydophila abortus.
Definition
-late term abortion storms
Term
How is Chlamydophila abortus transmited?
Definition
-oral
Term
What lesions do we see in response to Chlamydophila abortus in addition to abortion?
Definition
-thick leathery placenta with superficial exudate
Term
What is the name for disease caused by foothills abortion?
Definition
-epizootic bovine abortion
Term
Where does foothills abortion occur geographically?
Definition
-CA
Term
How is foothills abortion transmitted?
Definition
-Ornithodoras tick transmittion
Term
What lesions do you see on the fetus in response to foothills abortion?
Definition
-hepatomegaly, thymic atrophy, vasculitis
Term
Which serovar of Leptospirosis is seen in cattle? Swine?
Definition
-Hardjo and pomona
-Pomona and bratislava
Term
When during pregnancy does abortion occur due ot Leptospirosis?
Definition
-third trimester
Term
What lesions do you see on the fetus due to Leptospirosis?
Definition
-Ascites, fibrinous peritonitis
Term
What do we see in response to Listeria monocytogenes? Lesions in the dam? Lesions in the fetus?
Definition
-sproadic abortions in ruminants
-Dam: necrosuppurative placentitis
-FEtus: hepatomegaly and small yellow foci
Term
In which species is Listeria monocytogenes most important? Is it zoonotic?
Definition
-sheep
-yes
Term
What agents cause mycotic abortion?
Definition
-Aspergillus
-Phycomycetes: Mucor
Term
What lesions do you see on the placenta due to mycotic abortion?
Definition
-enlarged, brown, friable cotyledons
Term
What fetal lesions do you see due to mycotic abortion?
Definition
-dermatitis
Term
Which species are affected by herpes? What lesions do you see?
Definition
-cow, mare, sow, oat, dog
-hepatomegaly, multiple foci of ecrosis, splenic lymphoid necrosis, inclusion bodies
Term
Which cells does EHV-1 attack? What does this cause?
Definition
-uterine endothelial cells
-vasculitis, thrombosis, infarction of the endometrium
-leads to fluid loss of subsequent separation of the maternal and fetal layers of the placenta
Term
What fetal lesions do we see due to BVD?
Definition
-abortion, cerebelar hypoplasia, microphtalmia, and retinal dyspasia
Term
What lesions in the adult are caused by BVD?
Definition
-hemorrhagic thrombocytopenia
Term
What are the artiriviruses that cause abortion in the horse and pig?
Definition
-horses: EVAV
-pigs: PRRSV
Term
Which breeds of horses are more affected by EVA?
Definition
-Standerdbreds and Warmbloods
Term
What fetal lesions are seen in response to EVA?
Definition
-vasculitis and paintbrush hemorrhages
Term
What are the lesions seen in adult horses seen due to EVA? Who carries it?
Definition
-edema and vasculitis
-stallion
Term
How is Porcine Reproductve Respiratory Syndrome diagnosed?
Definition
-PCR and IHC
Term
What lesions are seen due to Porcine Repro Resp Syndrome?
Definition
-umbilical cord hemorrhages
-interstitial pneumonia in young and adult pigs
Term
Which animas are affected by Bluetongue? When during pregnancy does the resulting abortion occur? Vector?
Definition
-sheep and cattle
-third trimester
-Culicoides
Term
What are the three primary protozoal vectors of abortifactive diseases?
Definition
-Toxoplasma gondii
-Neospora caninum
-Tritichomonas foetus
Term
Describe the lifecycle of Toxoplasma gondii in general.
Definition
-Cat-sheep life cycle: ca ingests the sheep fetal membranes and the cat feces contaminate the sheep feeed
Term
Describe the fetal lesions seen due to Toxoplasma gondii.
Definition
-edema of the intercotyledonary chorioallantois, foci of inflammation, necrosis, and mineralization
Term
Which species is most commonly affected by NEospora caninum? When during pregnancy does abortion occur?
Definition
-dairy caows
-2nd trimester
Term
What lesions are seen in adult cattle due to Neospora caninum?
Definition
-inflammation in multiple organ systems
Term
What is a good diagnostic sample for Neospora caninum?
Definition
-brain
Term
What lesions are seen in the adult due to Tritrichomonas foetus?
Definition
-mild placentits
Term
What diagnostic sample do we collect to diagnose Tritrichomonas foetus?
Definition
-fetal stomach
Term
Where do we see Mare Repro Loss s
yndrome? Which breed is most commonly affected?
Definition
-Kentucky
-thoroughbreds
Term
What is the vector of Mare Repro Loss Syndrome?
Definition
-Eastern tent caterpillar
Term
What are the pathologies resulting from Mare Repro Loss Syndrome?
Definition
-early embryonic deaths
-red bag deliveries
-3rd trimester abortions
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