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XXY Chromosomes tricolor male cats with testicular hypoplasia |
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XX/XY Chromsomes more common anomaly |
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chromosomic sex does not fit with the phenotype XY female due to androgen insensitivity or receptor disorders due to SRY gene mutation |
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presence of both gonadal tissues ambiguous genitalia |
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presence of a singe type of gonadal tissue ovarian or testicular tissue usually see protruding clitoris |
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in twin bovine embryos anastomoses between placental vascular systems of two fetuses (one male and one female) male gonads develop earlier than female's testosterone alters female's cellular development ovotestes, hypoplastic uterine horns or lack of communication with vainga development of vesicular glands, short nonpatent vagina enlarged clitoris, small vulva, and prominent tuft of hair |
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aka imperforate vagina persistent membrane in zone of fusion of paramesonephritic duct with urogenital sinus secretions accumulate in vagina/uterus to cause mucometra/hydrometra |
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total lack of ovarian tissue can be unilateral or bilateral |
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seen commonly in cows can be unilateral or bilateral often associated with chromosomal anomalies like XXX and X_ |
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occurs in mare, cow, sow dark red mass on the surface of the ovary due to accumulation of blood in vessels |
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seen in mare remnants of embryonic ducts that fill with fluid |
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cystic rete ovary destroys tissue due to compression in the cat otherwise can be an incidental finding with little consequences |
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Ovarian Cysts in the Mare |
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Definition
epithelial inclusion cysts entrapped ovarian epithelial cells in ovary cause infertility due to size and number similar morphology of large follicles but do not disappear |
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Ovarian Cysts in Cows and Sows |
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Definition
cystic follicles are larger than normal persist more than 10 days without formation of CL ovulation doe snot occur and causes cystic ovarian degeneration half recover spontaneously due to deficit in LH production or LH receptors in the ovary due to cortisol inhibiting GnRH, LH release and LH receptors in ovary due to post-partum E.coli infections which produce prostaglandin and cortisol |
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occurs in cows and sows due to delayed or insufficient release of LH corresponds to failure of complete LH part of the cystic ovarian degeneration disorder estrous cycle is not affects and most are incidental findings |
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rare large round cells identical to seminoma in testes |
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rare mostly benign need to have at least 2 out of 3: ectoderm, endoderm, mesoderm |
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Sex Cord Stromal Neoplasms |
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Definition
from granulosa cells, theca cells, luteal cells, Sertoli cells solid, may be cystic mass may produce estrogen, inhibit, or testosterone E2 causes constant prolonged estus, cystic uterian hyperplasia Inhibit causes anestrus Testosterone causes virilism which the mare acts like a stallion |
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Definition
most common ovarian neoplasm in large animals unilateral, large mass solid, cystic/polycystic usually benign in large animals usually malignant in queen |
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Papillary Adenoma/Adenocarcinoma |
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Definition
occurs in dogs bilateral, cauliflower/smooth looks originate from epithelium frequently metastasized along abdominal organs or can embolize in vasculature and lymphatics |
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Segmental Aplasia of Uterine Horn |
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Definition
affected ovary is lumpy and enlarged from unovulated follicles |
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Definition
occurs in cow, ewe, sow due to chronic estrogen stimulation cystic endometrial hyperplasia is irreversible noncystic hyperplasia is reversible Cow-granulosa cell tumor, clover Ewe-clover, reduced fertility, enlarged mammary gland sow-mycotoxin from moldy feed |
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Definition
ocurs in ewes due to excessive metabolism of phytoestrogens in rumen ewes have infertility, due to failure of sperm to travel due to altered cervical mucous estrous cycle is normal with ovulation dysocia due to decreased myometrial tone uterine prolapse mammary development/lactation in nonpregnant ewes |
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Term
Cystic Endometrial Hyperplasia |
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Definition
common in dog progesterone influence after estrous causes cyst formation in mucosa provides environment for bacteria to grow and secondary pyometra occurs reversely, cystic hyperplasia can be caused by uterine infection and endometritis |
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Term
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Definition
bulging cyst from the endometrium, myometrium, or serosal surface usually incidental finding possibly due to trapped cells that fill with fluid |
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common in older bitches and queens localized pedunculated and causes obstruction large mass with one single pedicle |
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cow, bitch, queen endometrial glands proliferate into the myometrium focal, multifocal, or diffuse can be cystic |
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most susceptible during luteal phase due to progesterone induced immunosuppression likely to follow abnormal parturition or traumatic lacerations during parturition |
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inflammation of the uterus small amount of exudate in lumen neutrophil infiltration then lymphocytes, plasma cells, macrophages as it becomes more chronic fibrosis and cystic endometrial glands in chronic state due to a local infection or hematogenously during pregnancy |
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Contagious Equine Metritis |
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Definition
occurs in mares after foaling or coitus caused by Taylorella equigenitalis which is contagious and reportable temporary infertility and mucopurulent discharge is hallmark can cause permanent infertility |
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accumulation of suppurative fluid in uterus postpartum/postcoital localized and due to retained CL Arcnobacterum pyogenes, E.coli, Fusobacteriu, Strep, Staph |
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accumulation of suppurative fluid in uterus uncommon Streptococcus zooepidemicus, Klebsielle, E.coli, Actinomyces, Pasteurella, Pseudomonas |
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accumulation of suppurative fluid in uterus uterine wall is thick and doughy due to E.coli often follows cystic endometrial hyperplasia toxemia leads to PU/PD, bone marrow suppression, anemia, splenomegaly due to extramedullary hematopoiesis |
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occurs often in pregnant cow can occur in pyometra/mucometra greater than 180 degree turn results in dystocia, vascular compromised, edematous placenta, fetal death in dog/cat, fetus will rupture into peritoneum, mummifies, and attaches to serosa |
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occurs after parturition in cow, ewe, sow due to prolonged dystocia, hypocalcemia, phytoestrogens causes congestion, edema, infarction, trauma or uterus hemorrhage, shock, infection, infertility |
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occurs in ruminants, horses cow usually expels within 24 hours mare usually expels within 3 hours placenta becomes medium for bacterial growth |
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Subinvolution of Placental Sites |
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Definition
only in dogs, commonly young bitches unknown cause prolonged blood vaginal discharge after whelping no clinical signs and no response to tx thick hemorrhagic placental sites CLs always present |
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endometrial carcinoma lymphosarcoma (BLV) leimyoma |
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occurs mostly in dogs excision is curative |
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hyperestrogenism due to: mycotoxicosis in sow ovarian tumors estrus |
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Infectious Pustular Vulvovaginitis |
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Definition
Bovine Herpes Virus 1 highly contagious same virus causes IBR hyperemia of vagina/vulva with focal hemorrhage nodular epithelium and lymphoid hyperplasia erosion/ulceration see intranuclear inclusion bodies in epithelium |
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Definition
Equine herpesvirus 3 voital transmission ulcers and depigmented areas on vulva |
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Transmissible Venereal Tumor |
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Definition
occurs in dog during coitus same as in male reproduction |
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