Term
| Approaching menopause ______ & ________ decrease while _______ & _____ increase |
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Definition
| -Estrogen & Inhibin -FSH & LH |
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Term
| In menopause ______ increases because of the decrease of negative feedback by _____ & _______ |
|
Definition
-FSH (& LH)(less)
-estrogen & inhibin |
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Term
| The increase in ______ in the beginning of menopuase produces _______ (longer or shorter) cycles |
|
Definition
FSH
shorter (by shortening the time of the follicular phase) |
|
|
Term
| Menstrual cycles become longer when |
|
Definition
| the time required to develop positive feedback(high estrogen) is prolonged |
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Term
| Nearing menopause most cycles are anovulatory because not enough _______ is produced to trigger _________ |
|
Definition
|
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Term
| Some ovarian secretion of ______ continues after menopause, but it gradually diminishes |
|
Definition
|
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Term
| After menopuase ovaries continue to synthesize _______ (under the influence of LH) and therefore these levels don't decline much. |
|
Definition
|
|
Term
| The production of estrogen from androgens in the ovaries after menopause is minimal because there are few _______ left |
|
Definition
| primordial follicles (and thereby much fewer granulosa cells) |
|
|
Term
| After menopause androgens are converted to estrogen by _______(enzyme) in the ______ tissues. |
|
Definition
-aromatase
-peripheral (adipose & muscle) |
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|
Term
| Peripheral aromatase has a higher affinity for __________ (androgen) therefore plasma levels of ________(estrogen) are higher after menopause. |
|
Definition
|
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Term
| ________(androgen) is a precursor of _______ (estrogen) |
|
Definition
-testosterone to estradiol
-androstenedione to estrone |
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|
Term
| _________(estrogen) levels after menopause are higher than ________(estrogen) due to |
|
Definition
-Estrone (E1)
-estradiol (E3)
-Change to peripheral production of estrogen instead of ovarian. |
|
|
Term
Charachteristics changes in hormone levels post-menopause:(increase, decrease or unchanged)
FSH ________
LH _________
Estrone_________
Estradiol_____
Androgens _______ |
|
Definition
FSH increases (FSH>LH)
LH Increases
Estrone increases
Estradiol decreases
Androgens unchanged |
|
|
Term
FSH >LH during ________ (ages)
LH > FSH during _______ |
|
Definition
childhood and menopause
Reproductive period |
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