Term
|
Definition
|
|
Term
Common threats to internal validity (3) |
|
Definition
1) Bias, 2) confounding, 3) chance |
|
|
Term
Confoundings are associated with: exposure or disease |
|
Definition
|
|
Term
Ways to avoid confounding (3) |
|
Definition
1) Randomization, 2) matching, 3) statistical adjustment |
|
|
Term
Randomization requires what kind of study design |
|
Definition
|
|
Term
Matching requires assessment of what during study design |
|
Definition
Confounders to determine who to match |
|
|
Term
After recognizing a confounder, the ___ relative risk is statistically modified to get the ___ relative risk |
|
Definition
|
|
Term
If the crude & adjusted relative risks are different, then the was there a confounder: yes or no |
|
Definition
|
|
Term
If the crude & adjusted relative risks are the same, then the was there a confounder: yes or no |
|
Definition
|
|
Term
Failure to adjust for a confounder leads to determing there is a statistical significance where there is not: is this type I or II error |
|
Definition
Type I: detection of an effect when there is not an effect (a "false positive") |
|
|
Term
Multivariable logistic regression used for: categorical, continuous, or time-to-event outcome |
|
Definition
|
|
Term
Multiple linear regression used for: categorical, continuous, or time-to-event outcome |
|
Definition
|
|
Term
Multivariable Cox regression used for: categorical, continuous, or time-to-event outcome |
|
Definition
|
|
Term
y=ax+b is what kind of regression |
|
Definition
|
|
Term
If correlation coefficient=0 then what can you conclude |
|
Definition
|
|
Term
If correlation coefficient>0 then what can you conclude |
|
Definition
|
|
Term
If correlation coefficient<0 then what can you conclude |
|
Definition
|
|
Term
If correlation coefficient=100 then what can you conclude |
|
Definition
Math error: r is between -1 and +1 |
|
|
Term
Kaplan-Meier curves plot what vs. what |
|
Definition
Time vs. whatever being measured (e.g., mortality) |
|
|
Term
Median survival time on a Kaplan-Meier curve is determined how |
|
Definition
Finding where the plot crossing y=0.5 and finding the time (x value) where 0.5 is crossed |
|
|
Term
Cox regression permits you to measure __ ratios |
|
Definition
|
|
Term
For mortality, if the hazard ratio=1 then what can you conclude |
|
Definition
No difference between groups |
|
|
Term
For mortality, if the hazard ratio>1 then what can you conclude |
|
Definition
Treatment/exposure/disease suggests harm: HR>1 means they are more likely to be harmed |
|
|
Term
For mortality, if the hazard ratio<1 then what can you conclude |
|
Definition
Treatment/exposure/disease suggests benefit: HR<1 means they are less likely to be harmed |
|
|
Term
Does statistical significance mean clinical significance: yes or no |
|
Definition
|
|
Term
Measurements of treatment effects are made under relatively ideal conditions: efficacy or effectiveness |
|
Definition
|
|
Term
Measurements of treatment effects are made under “real-world” conditions: efficacy or effectiveness |
|
Definition
|
|
Term
Typically an aim of randomized clinical trials: efficacy or effectiveness |
|
Definition
|
|
Term
Which is partly affected by adherence: efficacy or effectiveness |
|
Definition
|
|
Term
|
Definition
How well patients followed the treatment plan |
|
|
Term
Cross-sectional study: observational or experimental study |
|
Definition
|
|
Term
Case-control study: observational or experimental study |
|
Definition
|
|
Term
RCT: observational or experimental study |
|
Definition
|
|
Term
Cohort study: observational or experimental study |
|
Definition
|
|
Term
Case control study: retrospective or prospective study |
|
Definition
|
|
Term
Why might a case control study be done |
|
Definition
|
|
Term
Can you calculate incidence from a case control study |
|
Definition
No, researchers picked subjects |
|
|
Term
Case control study can use: relative risk or odds ratio |
|
Definition
|
|
Term
If odds ratio=1, then what can you conclude |
|
Definition
No association of exposure & disease |
|
|
Term
If odds ratio>1, then what can you conclude |
|
Definition
Exposure associated with increased odds of disease |
|
|
Term
If odds ratio<1, then what can you conclude |
|
Definition
Exposure associated with decreased odds of disease |
|
|
Term
|
Definition
OR=(a/b)/(c/d) [ratio of row ratios] |
|
|
Term
Pertaining to who is in a study: selection or information bias |
|
Definition
|
|
Term
Pertaining to what is in a study: selection or information bias |
|
Definition
|
|
Term
Someone in a case control study over-reports their exposures: this is what kind of bias |
|
Definition
|
|
Term
Recall bias is a type of: selection or information bias |
|
Definition
|
|
Term
Classification by exposure: cross-sectional, cohort, case-control |
|
Definition
|
|
Term
Classification by outcome: cross-sectional, cohort, case-control |
|
Definition
|
|
Term
Classification by exposure AND outcome simultaneously: cross-sectional, cohort, case-control |
|
Definition
|
|
Term
A survey asking for various exposures and various symptoms would be what kind of study |
|
Definition
|
|
Term
Cross-sectional studies generally allow estimation of: incidence or prevalence |
|
Definition
|
|
Term
Case studies & series are what kind of study |
|
Definition
|
|
Term
Which describe a single patient: case studies or case series |
|
Definition
Case studies describe a single patient |
|
|
Term
|
Definition
|
|
Term
When is external validity checked |
|
Definition
After internal validity is checked |
|
|
Term
If a confounder is in the causal pathway between exposure & outcome, it is instead what |
|
Definition
|
|
Term
Should you statistically adjust for counfounding variables: yes or no |
|
Definition
|
|
Term
Should you statistically adjust for mediating variables: yes or no |
|
Definition
No, if you do then you will remove some of the desired effect |
|
|
Term
It depends: confounder, mediating, effect modification |
|
Definition
|
|
Term
Statistically biases & obscures your desired relationship: confounder, mediating, effect modification |
|
Definition
|
|
Term
Partially responsible for desired effect: confounder, mediating, effect modification |
|
Definition
|
|
Term
Muscle strength: normal strength = |
|
Definition
|
|
Term
Muscle strength: can overcome gravity but not resistance = |
|
Definition
|
|
Term
Muscle strength: cannot overcome gravity = |
|
Definition
|
|
Term
Muscle strength: flicker of movement only = |
|
Definition
|
|
Term
Muscle strength: no movement = |
|
Definition
|
|
Term
Liver starts at what vertebral level |
|
Definition
|
|
Term
|
Definition
|
|
Term
What line should you percuss the liver |
|
Definition
|
|
Term
Checking venous flow of the abdomen, blood flows away from the umbilicus: disgnosis |
|
Definition
|
|
Term
Checking venous flow of the abdomen, blood flows superiorly above & below umbilicus: disgnosis |
|
Definition
Inferior vena cava obstruction |
|
|
Term
|
Definition
6th rib, anterior axillary line, costal margin |
|
|
Term
Types of abdominal pain (4) |
|
Definition
1) Colic, 2) ache, 3) peritoneal, 4) referred |
|
|
Term
Liver pain is referred to where |
|
Definition
|
|
Term
Pancreatitis pain is referred to where |
|
Definition
Right costal margin & left shoulder |
|
|
Term
Patient would lie still for: pancreatitis or renal colic |
|
Definition
|
|
Term
Patient would writhe around for: pancreatitis or renal colic |
|
Definition
|
|
Term
Involuntary; secondary to peritoneal tenderness: guarding or rigidity |
|
Definition
|
|
Term
Resistance to palpation: guarding or rigidity |
|
Definition
|
|
Term
McBurney's point connects which two landmarks |
|
Definition
|
|
Term
Provides evidence based summaries with evidence ratings for a wide range of diseases and drugs |
|
Definition
|
|
Term
A comprehensive literature database of life sciences and biomedical information |
|
Definition
|
|
Term
MeSH search lets you search by what |
|
Definition
|
|
Term
|
Definition
To track changes as diagnostic tool |
|
|
Term
2nd percentile for height indicates child is __ [short or tall] for his/her age |
|
Definition
|
|
Term
Are patients with Turner's ___ [slower, normal, or faster] growers than non-Turner |
|
Definition
Slower ∴ need different growth charts |
|
|
Term
Does the "obese if BMI ≥30" rule apply to children: yes or no |
|
Definition
|
|
Term
At which age do children have the lowest BMI |
|
Definition
|
|
Term
At which age do infants have the highest BMI |
|
Definition
|
|
Term
BMI percentile of age 2-18 that is a strong PPV of adult obestiy |
|
Definition
>99% at age 2-18 is strong PPV of adult obesity |
|
|
Term
Height velocity is maximal at what age |
|
Definition
|
|
Term
When do height velocities diverage between sexes |
|
Definition
|
|
Term
Peaks of weight velocity (2) |
|
Definition
1) < 6 months, 2) peak of puberty (♀=13, ♂=15) |
|
|