Term
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Definition
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Term
Cardiovascular physiology extracts ____ of oxygen from coronary blood flow (CBF) |
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Definition
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Term
Myocardial oxygen consumption MVO2 is ___ and increases with demand (contractility and HR) |
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Definition
dependent of CBF CBF increases 4-6 fold to meet demand |
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Term
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Definition
inadequate oxygen supply results in pain -angina pectoris: chest pain -claudication=pain in periphery -aching/cramping associated with physical activity, eased by rest |
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Term
Complications of inadequate oxygen supply |
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Definition
-decreased SV -reduced ejection fraction -reduced cardiac output (increase HR to meet demand) -decreased perfusion pressure (decreased muscle perfusion) -infarct when inadequate oxygen supply duration is too long |
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Term
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Definition
coronary atherosclerosis (artery) disease |
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Term
Peripheral artery disease (PAD) |
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Definition
6x increase in CAD 5x increase in cerebrovascular events thinkening and loss of elasticity (progressive insufficiency) can lead to ischemia and pain |
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Term
CAD: occurs within endothelium |
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Definition
endothelium dysfunction vascular inflammation accumulation of: -lips -macrophages -blood clotting-elements -calcium -connective tissue - fibrous (scar) |
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Term
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Definition
chronic progressive -formation of atheromatous plaques/lesions -vascular remodeling -luminal stenosis -occlusion of blood flow |
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Term
Occlusion of blood flow (1) |
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Definition
1-2 min results in loss of contraction -transient reduction in flow=ischemia -prolonged ischemia=myocardial infarction (MI) |
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Term
Occlusion of blood flow (2) |
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Definition
Sufficient blockage=MI -gross necrosis of myocardium:leads to permanent loss of contraction -blockage: reduction in lumen diameter, length of plaque, effect on blood flow |
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Term
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Definition
increase potential for fissure, rupture (thrombosis and perhaps embolism), swelling, combination sudden alteration can lead to acute infarct |
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Term
CAD location of blockage is significant |
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Definition
-most at curves or branches ->50% blockage of major coronary arteries is clinically significant -exacerbated by: hemorrhage, ulceration, calcification, thrombosis |
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Term
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Definition
-elevated LDL -reduced HDL -atherogenic diet -elevated inflammation |
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Term
Angina pectoris: blood flow is |
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Definition
adequate at rest, inadequate during exercise ischemia=pain=angina |
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Term
symptoms of angina pectoris |
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Definition
-heavy, squeezing, constricting feeling behind sternum that radiates to shoulders, arms, neck, and/or jaw -shortness of breath -nausea -diaphoresis -sharp, stabbing pain -2-10 minutes |
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Term
Non cardiac causes of angina pectoris |
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Definition
-esophageal spasm -acid reflux -hiatal hernia -chest wall bone or cartilage inflammation -muscular pain |
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Term
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Definition
-associated with specific level of exertion, emotional stress, and/or cold exposure -result of fixed stenosis -relieved with rest or sublingual nitroglycerin |
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Term
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Definition
-unpredicted onset -at rest or awakening from sleep, lasting >20 min -new onset -increasing severity, frequency, duration, or threshold |
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Term
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Definition
coronary artery spasm -typically not associated with high levels of stenosis or atheroma |
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Term
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Definition
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Term
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Definition
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Term
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Definition
severe, very uncomfortable |
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Term
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Definition
most severe pain ever experienced |
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Term
Myocardial Infarction location, types, coronary circulation involvement and location: |
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Definition
-left ventricle -2 types transmural infarction (Q-wave infarct) subendocardial infarction (non-Q-wave) -anterior wall, inferior wall |
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Term
Signs/symptoms of Myocardial Infarction |
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Definition
-severe, prolonged chest pain/pressure (may radiate to arms, back, or neck) -sweating -nausea -vomiting -hematological: increased serum CK-MB, troponin I > 0.5ng/mL |
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Term
Myocardial Infarction Signs and Symptoms on the ECG: |
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Definition
-transitory -ST segment elevation -T wave inversion -prolonged due to irreversible necrosis pronounced Q waves |
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Term
Exercise Response (Myocardial Infarction) |
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Definition
-reduced cardiorespiratory fitness -reduced cardiac output -SA node or AV node disease -increased ventricular arrhythmias -ECG: ST segment depression -angina -medications may reduce HR and/or BP |
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Term
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Definition
heart weakened and enlarged |
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Term
Restrictive Cardiomyopathy |
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Definition
chambers are unable to fill because of stiffness |
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Term
hypertrophic cardiomyopathy (HCM) |
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Definition
heart muscles become thick |
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Term
Causes of cardiomyopathy: |
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Definition
-alcoholism and cocaine use -chemotherapy drugs -pregnancy -genetic defects -amyloidosis -end-stage kidney disease -infections due to viruses -long term, severe high BP -nutritional deficiencies -systemic lupas erythematosus |
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Term
Rhythm Abnormalities: Atrial Fibrillation |
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Definition
disorganized atrial activity leads rapid and irregular ventricular depolarizations |
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Term
Signs and symptoms of Rhythm abnormalities |
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Definition
-increased risk of thromboembolic events -ventricular tachycardia -incomplete ventricular filling - reduced stroke volume -decreased exercise capacity -fatigue |
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Term
Atrial fibrillation is associated with: |
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Definition
-CHF -cardiomyopathy -valvuar disease -CAD -hypertension -hyperthyroidism |
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Term
Exercise Response in Atrial Fibrillation |
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Definition
-rapid, irregular ventricular response -elevated HR -elevated HR max -increased HR variability -reduced tolerance |
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Term
Atrial Flutter definition |
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Definition
abnormality of heart rhythm -resulting in a rapid and sometimes irregular heartbeat electrical impulses take abnormal path through the atria -250-350bpm, slower at AV node heart beats in a regular rapid rhythm supraventricular paroxysmal persistent rarely life-threatening |
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Term
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Definition
-abnormalities/diseases -diseases elsewhere -consuming substances after open heart surgery -no underlying causes may be found |
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Term
Symptoms of atrial flutter |
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Definition
-none -palpitations -fluttering -shortness of breath -anxiety -weakness -angina pectoris -feeling faint -syncope |
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Term
Ventricular Tachycardia (VT) definition |
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Definition
>100 (or 120) bpm arising distal to bundle of His reduced stroke volume combined with ventricular fibrillation=50% of sudden cardiac death |
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Term
Causes of Ventricular Tachycardia |
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Definition
-ischemic heart disease -nonischemic cardiomyopathies -ion channel abnormalities -other conditions in which cardiac function and structure are normal |
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Term
Types of ventricular tachycardia (VT) |
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Definition
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Term
symptoms of tachycardia (VT) |
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Definition
syncope palpitations dyspnea sudden death |
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Term
Ventricular fibrillation (VF) definition |
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Definition
disorganized rapid ventricular rhythm collapse or become unconscious may be precluded by: -chest pain -dizziness -nausea -rapid heart beat -shortness of breath |
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Term
Causes of Ventricular Fibrillation (VF) |
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Definition
-congenital heart disease -electrocution or injury -MI -cardiomyopathies -heart surgery -ischemia -commotio cordis -no history of heart disease, but have risk factors |
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Term
Valvular Heart Disease (VHD) definition |
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Definition
leakage due to damage or disease compromises blood flow |
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Term
Leakage due to damage or disease compromises blood flow -Infection -Congenital defects -aging |
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Definition
-rheumatic fever (of major concern when impacts heart, rheumatic heart disease RHD) endocarditis infection typically occurs during dental procedures, surgery, IV drug use, or with severe infections -genetic abnormalities intrauterine environment errors of morphogenesis infection chromosomal abnormality |
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Term
Symptoms and complications are disease dependent (Valvular Heart Disease) |
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Definition
-valves involved -valve disorder (stenosis, regurgitation) -severity (other complications) -fatigue -palpitations -angina -blood pressure changes -extreme fatigue -weakness -dizziness -coughing -shortness of breath -edema -rapid weight gain |
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Term
Symptoms of Valvular Heart Disease (VHD) |
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Definition
physical exam -heart sounds -lung sounds -circulation and the functioning of other organs |
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Term
Diagnostic tests for valvular heart disease |
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Definition
-echocardiography (transthoracic, transesophageal) -doppler ultrasound -cardiac catheterization -magnetic resonance imaging (MRI) |
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Term
3 specific valvular disorders |
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Definition
-Mitral valve prolapsed (MVP) -mitral stenosis -mitral regurgitation *you can read about others in the text |
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Term
Treatment of Valvular disorders and goals of treatment |
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Definition
-depends on the type and severity of valve disease -protect valve from further damage -symptom reduction -repair or replace valve |
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Term
Exercise response to vavular disorders |
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Definition
effect ranges from no effect to limiting physical activity due to increased risk -tachycardia and atrial fibrillation -hypotension due to decreased cardiac output -angina -dyspnea -syncope -ST segment depression |
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Term
Chronic (Congestive) Heart Failure (CHF- Myocardial dysfunction) |
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Definition
inability of heart to adequately deliver blood oxygen to tissues -decreased ejection fraction (normal=55%, CHF=35% |
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Term
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Definition
-narrowed coronary arteries (CAD) -past MI w/ scar tissue -high blood pressure -heart valve disease -cardiomyopathy -congenital -endocarditis and/or myocarditis |
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Term
CHF principal hemodynamic changes |
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Definition
-decreased during exercise, progressing to rest as well -increased L ventricular filling pressure -compensatory ventricular volume overload -elevated pulmonary and central venous pressure -secondary organ alterations -disturbed muscle metabolism -impaired vasodilation -renal insufficiency = Na+ and water retention |
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Term
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Definition
systolic dysfunction diastolic dysfunction combined dysfunction |
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Term
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Definition
-fatigue, weakness, faintness -dyspnea -reduced exercise tolerance -cough -edema -weight gain -irregular or rapid pulse -palpitations -difficulty sleeping -loss of appetite, indigestion -additional: decreased alterness or concentration, decreased urine production, nausea and vomiting, need to urinate at night |
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Term
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Definition
-reduced exercise tolerance -reduced cardiac output resulting in dyspnea -reduced oxygen delivery to muscles with increased lactate accumulation and long term reduction in mitochondrial volume density and fiber transition to type II -fatigue -reduced HR and BP responses |
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Term
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Definition
-medications -limit salt intake -weight daily -stay active - dont exercise on days with weight gain -lose weight if overweight -get enough rest -keep feet elevated when resting |
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Term
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Definition
-increases risk for stroke, CAD, renal disease, and death -primary (essential) hypertension -secondary hypertension |
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Term
Hypertension Exercise Responses |
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Definition
-tends to be exaggerated or diminished -diastolic tends to increase -decrease post exercise -chronic aerobic physical activity decreases hypertension -chronic resistance training decreases hypertension - not as much as aerobic |
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Term
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Definition
-limit alcohol intake -limit salt intake -increase intake of fiber, fruits, vegetables, and low fat dairy -stay active -lose weight if overweight -medications |
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Term
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Definition
-Grade 0: asymptomatic 1: intermittent claudication 2: ischemic pain at rest 3: tissue loss |
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Term
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Definition
>1: normal <0.95: significant narrowing <0.8: pain in lower extremity <0.4: ischemic pain at rest <0.25: limb threatening |
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Term
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Definition
-increase blood flow -redistribute blood flow -reduced blood viscosity -increased aerobic metabolism -improved economy |
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Term
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Definition
localized, blood-filled dilation of a blood vessel caused by disease or weakening of vessel wall -most commonly in circle of Willis and aorta -as size increases, there is increased risk of rupture -complicated by CAD/PAD, smoking, hypertension, and other diseases/disorders of circulation |
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Term
Cardiovascular disease treatment objectives |
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Definition
-reduce myocardial oxygen demand with medications or exercise -increase myocardial oxygen supply with medications, surgery, exercise -combination of objectives |
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Term
Increasing myocardial oxygen supply |
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Definition
surgery- revascularization coronary artery bypass graft (CABG) - use vein or artery from elsewhere |
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Term
CABG Indications, complications, success, relief |
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Definition
-relieve angina that does not respond to pharmacotherapy -PTCA contraindicated -prolong life when major coronary arteries are blocked -preserve left ventricular function -MI: 5-12% -graft occlusion -1yr:90% 5yr:80% 11yr:60% 5yr:70% 10yr:50% |
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Term
Surgery- Revascularization |
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Definition
percutaneous transluminal coronary angioplasty (PTCA) or percutaneous coronary intervention (PCI) -compress and redistribute plaque -stretch vessel adjuncts -stent placement: durg eluting - sirolimus |
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Term
Surgery - Revascularization Indications and Complications |
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Definition
-same as CABG, but less severe -restenosis: 5-7% w/ drug eluting stent -bleeding at catheter insertion -vessel damage at insertion site -vessel damage at PTCA site -infarction at insertion -myocardial infarction -dysrhythmias. arrhythmias -angina -coronary artery rupture |
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Term
Rhythm modifiers or pacing techniques problem: |
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Definition
disruptions to normal rhythm, synchronization, and HR can reduce coronary and system blood flow -typically due to node issues |
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Term
rhythm modifiers or pacing techniques purpose: |
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Definition
to re-establish normal sinus rhythm, atrioventricular synchronization, and responsiveness of HR -improve symptoms, enhance responsiveness to physical activity, and improve quality of life |
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Term
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Definition
-pulse generator -pacing wires (sensing, pacing) |
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Term
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Definition
-sick sinus syndrome -atrioventricular (AV) block -neurally mediated syncope -carotid sinus hypersensitivity -exaggerated response to baroreceptor input |
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Term
Implantable cardiac defibrillator (ICD) |
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Definition
electrically terminate life threatening arrhythmias components: leads-track cardiac rhythm cardioverter defibrillator |
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Term
Acute Transplant Rejection Prevention: Chemotherapeutic drugs |
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Definition
suppress immune system -short course: high dose corticosteroids -triple therapy regimen: more challenging potential for rejection can be used (corticosteroid, calcineurin inhibitor, anti proliferative agent) -high risk patients: add antibodies against specific components of immune |
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Term
Transplant Rejecetion Chemotherapeutic Drugs |
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Definition
Calcineurin inhibitors: -protein phosqhatase that activates T cells -ciclosporin -tacrolimus mTOR inhibitors -used form those who cannot tolerate others -protein: regulates cell growth, proliferation. motility, survival, protein synthesis, transcription -sirolimus -everolimus anti-proliferatives -azathioprine -mycophenolic acid corticosteriods -prednisolone -hydrocortisone antibodies -monoclonal anti-IL-2Ra receptor antibodies (basiliximab, daclizumab) -polyclonal anti-t-cell antibodies (anti-thymocyte globulin (ATG) and anti-lymphocyte globulin (ALG)) |
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Term
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Definition
smoking cessation lipid and lipoprotein modification reduce clotting medications hypertension control diabetes management increase physical activity weight reduction medical management |
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Term
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Definition
exercise, medications, and PTCA seem to be equally effective |
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Term
Control of demand and supply |
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Definition
dilate, reduce volume, reduce pumping rate |
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Term
Medications to control demand and supply |
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Definition
dialate: nitrates, angiotension converting enzyme (ACE) inhibitors, CA++ channel blockers reduce volume: diuretics reduce pumping rate: B blockers reduce pumping force: Ca++channel blockers, B blockers |
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Term
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Definition
reduce Ca++ availability by increasing Ca++ uptake by sarcoplasmic reticulum |
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Term
What do ACE inhibitors do? |
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Definition
reduce the production of the potent vasoconstrictor, angiotensin |
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Term
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Definition
affect the loop of henley to reduce water reabsorption by the kidneys |
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Term
What do beta blockers do? |
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Definition
block the effect of adrenergic stimulation on heart rate and contractility |
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|
Term
what do calcium channel blockers do? |
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Definition
reduce the influx of Ca++ during a cardiac action potential reduce contractility and increases smooth muscle compliance |
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Term
FITT for Cardiac Disease Inpatient |
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Definition
F:2-4/d to 2/d with increased duration I: to tolerate, RPE 13,HR 120 or resting +20, HR+30 (after surgery) T:3-5 min, 2:1 ratio, progress to 10-15 min T:dynamic, rhythmic using large muscles |
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Term
FITT for Cardiac Disease Outpatient |
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Definition
F:4-7d/wk I:to tolerate, RPE 11, 40-80% HRR and oxygen consumption reserve, at HR below ischemic threshold T: warmup/cool down 5-10 min, 20-60 min, start at comfort level T:dynamic, upper and lower body, lifestyle physical activity |
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Term
FITT for cardiac disease outpatient without exercise or pharmocological test |
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Definition
F:4-7d/wk I:resting+20, 2-4 mets, RPE 11-14, monitoring ECG, BP and ischemia T: 5-10, 20-60 min, start at comfort T: dynamic, upper/lower body, lifestyle |
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Term
FITT for cardiac outpatient with pharmacological test (no ischemia) |
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Definition
F: 4-7d/wk I:70-85% HRmax, 2-4 met, RPE 11-14, monitoring T: 5-10, 20-60, start at comfort level T: dynamic, upper/lower, lifestyle |
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Term
FITT for cardiac disease outpatient with pharmacological test (ishemia elicited) |
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Definition
F:4-7d/wk I:10bpm under threshold, 2-4mets, RPE 11-14, monitoring T: 5-10min, 20-60 min, start at comfort level T:dynamic, upper/lower, lifestyle |
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Term
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Definition
no symptoms no more than one of the following risk factors: >45 men, >55 woman parental heart attack tobacco use hypertension high cholesterol diabetes sedentary exercise: moderate and vigorous without physician approval |
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Term
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Definition
two or more risk factors signs/symptoms of: cardiopulmonary or metabolic diseases, chest pain, arm pain, S.O.B., dizziness/fainting, ankle swelling, irregular heart beat/murmur Exercise: moderate w/out physician approval, vigorous requires physician approval |
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Term
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Definition
known cardiac, pulmonary, and/or metabolic disease exercise:physician approval required |
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Term
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Definition
F:moderate 5d/wk, vigorous 3d/wk, or combination of 3-5 I:moderate: 40-60%VO2reserve, vigorous:60 or more % VO2reserve T: 150min/wk or 30 min/d, 1000kcal/wk, 10000 steps, continuous or accumulated, dose responsive T:aerobic, muscular strength, muscular endurance, flexibility, body composition, neuromuscular (balance, agility) |
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Term
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Definition
206.9-(0.67xage) Range: low-high |
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Term
Ways to monitor intensity: |
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Definition
HRR VO2reserve RPE talk test affective valence energy expenditure %HRmax %VO2 mets |
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Term
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Definition
reduces incidence of cumulative trauma injuries increases interest/reduces boredom enhances adherence |
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Term
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Definition
multijoint (compound) movements major muscle groups (chest, shoulders, upper back, lower back, abdomen, hips, legs) 2-4 sets/muscle group 2-3 min rest between sets 8-12 reps/set 60-80% 1RM |
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Term
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Definition
10 minutes major muscle tendon groups passive active ballistic-specific PNF >4 sets/group limits of discomfort |
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Term
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Definition
balance agility proprioception particularly older adults |
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Term
Recommendation for strength for adults |
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Definition
2-3d/wk muscular strength and endurance resistance exercise calisthenics balance agility exercises |
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Term
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Definition
goals abilities health experience equipment individual differences maintenance taper detraining retraining |
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Term
Guidelines for functional capacity |
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Definition
>7 mets for all risk levels |
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Term
Responses to acute exercise during pregnancy compared with prepregnancy |
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Definition
increased oxygen uptake increase heart rate increase stroke volume increase cardiac output increase tidal volume increase minute ventilation increase ventilatory equivalent for oxygen no change/decrease in systolic BP no change/decrease in diastolic BP |
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Term
Relative contraindications for exercising during pregnancy |
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Definition
severe anemia unevaluated maternal cardiac dysrhymthia chronic bronchitis poorly controlled type one diabetes mellitus extreme morbid obesity extreme underweight history of sedentary lifestyle intrauterine growth restriction in current pregnancy poorly controlled hypertension orthopaedic limitations poorly controlled seizure disorder poorly controlled hyperthyroidism heavy smoker |
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Term
absolute contraindications for exercising during pregnancy |
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Definition
hemodynamically significant heart disease restrictive lunge disease incompetent cervix/cerclage multiple gestation at risk for premature labor presistent second or third trimester bleeding placenta previa after 26 weeks of gestation premature labor during the current pregnancy rupturee membranes preeclampsia/pregnancy-induced hypertension |
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Term
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Definition
F: >3d/wk I: moderate 40-60% oxygen consumption reserve, Heart Rate is less reliable - use RPE or talk test T: >15 min/d building to 30 min T: dynamic |
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Term
Responses to exercise of children compared to adults |
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Definition
lower absolute oxygen uptake higher relative oxygen uptake higher heart rate lower cardiac output lower stroke volume lower systolic BP lower diastolic BP higher respiratory rate lower tidal volume lower minute ventilation lower respiratory exchange ratio |
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Term
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Definition
F: >3d/wk I:moderate T: >30min/d moderate, >30 min/d vigorous (60 min/d total) T: variety |
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Term
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Definition
stimulates immature stem cells to differentiate into muscle and bone cells rather than fat cells |
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Term
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Definition
unchanged RHR lower HRmax lower max cardiac output higher resting and exercise blood pressure lower max oxygen uptake reserve higher residual volumes lower vital capacities slower reaction time lower muscular strength lower flexibility lower bone mass lower fat free body mass higher percent body fat lower glucose tolerance longer recovery time |
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Term
Older people FITT (Aerobic) |
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Definition
F and I:>5d/wk moderate (RPE 5-6), >3d/wk vigorous (RPE 7-8) T:30-60 min T: variety w/ limited orthopedic stress |
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Term
Older people FITT (Muscular Strength) |
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Definition
>2d/wk mod/vig 5-8 8-10 exercises, 10-15 reps progressive wt training or wt bearing |
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Term
Older people FITT (Flexibility) |
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Definition
>2d/wk moderate RPE: 5-6 static |
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Term
Older people FITT (Balance) |
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Definition
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Term
|
Definition
disorientation, dizziness, irrational behavior, apathy, headache, vomiting, hyperventilation, wet skin disoriented, unresponsive, above 40degree C |
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Term
Exertional Heat Exhaustion |
|
Definition
low blood pressure, elevated HR and RR, wet and pale skin, headache, weakness, dizziness, decreased muscle coordination, chills, nausea, vomiting, diarrhea little or no mental change, agitated 37-40 degrees C |
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Term
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Definition
depressed HR and RR, pale skin, sensation of weakness, tunnel vision, vertigo, nausea, syncope brief feinting episode little or no change in core temp |
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Term
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Definition
feeble, localized, wandering spasms that may progress to debilitating cramps no change in mental status 37-40 degrees C |
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Term
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Definition
measure from heels to tips of fingers lower score=better |
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Term
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Definition
cross=+ touch=0 fail to meet=- measure fingertips |
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Term
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Definition
forehead or chin stays on ground measure bottom of stick to floor greater distance=better score |
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Term
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Definition
measure bicromial width reverse, thumb grip out move in one inch at a time subtract bicromial distance smaller#=better score |
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Term
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Definition
hold for 2 seconds score is farthest part of fingertips greater distance=better score |
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Term
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Definition
prone interlock fingers behind neck measure from floor to bottom of chin greater distance=better score |
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Term
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Definition
shoulder height can slightly bend knees, keep vertical make fist hold 2 seconds greater distance = better score |
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Term
Astrand Rhyming Cycle Ergometer (sub max testing) |
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Definition
single stage test lasting 6 minutes depending on gender and conditioning status 50rpm HR between 125-170 RH measured in 5th and 6th minute average is used to estimate monogram to estimate VO2 multiply by correlation factor (1 for our age group) |
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Term
YMCA Cycle (sub max testing) |
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Definition
2-4 three minute stages raise steady state heart rate between 110 and 70% HRR (or 85% HRmax)for two stages each work rate performed for 3 minutes HR taken in the last 30 seconds of stage if heart rates vary by more than 5 bpm, do the stage for one more minute HR of last state is measured against work rate extrapolate the line to fine VO2max |
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Term
Astrand Rhyming Step Test (sub max testing) |
|
Definition
33cm women, 40 cm men use monogram to determine VO2max |
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Term
Ebbling Single stage treadmill test (sub max testing) |
|
Definition
find THR 50-70% of age predicted set at comfortable walking (2.0-4.5mph) for 4 min and 0 grade should reach THR during this stage after 4 min, keep same speed go up to 5% grade for 4 min use equation to find VO2max |
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Term
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Definition
<100 is optimal 100-129 is near optimal 130-159 boderline high 160-189 high >190 very high |
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Term
|
Definition
<200 desirable 200-239 borderline high >240 high |
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Term
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Definition
|
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Term
|
Definition
<150 normal 150-199 borderline high 200-499 high >500 very high |
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Term
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Definition
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