Term
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Definition
| Action potential spreads through plasma membrane and down T tubules |
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Term
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Definition
| Voltage Channels on the SR open and release Ca2+ into the cytosol |
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Term
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Definition
| Voltage-gated Ca2+ channels on the plasma membrane allow Ca2+ into the cell |
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Term
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Definition
| SR released more Ca2+ with each action potential in a phenomenom known as calcium-induced calcium relesase. Calcium binds to troponin shifting tropomyosin off the myosin binding sites on actin. |
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Term
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Definition
| Cross-bridge cycle occurs |
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Term
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Definition
Relaxation of the cardiac muscle occurs when Ca2+ exits the cytosol in three separate mechanisms.
1. Ca2+-ATPase actively transports Ca2+ from the cytosol into the lumen of the SR
2. Ca2+ ATPase actively transports Ca2+ from the cytosol into the interstitial fluid.
3. Na+ Ca2+ exchanger in the plasma membrane actively transports Ca2+ out of the cell by countertransport with sodium. |
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