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EXAM2:Pharm L22
Derm drug reactions
13
Medical
Graduate
05/30/2009

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Cards

Term
Warfarin
Definition
Anti-coagulant. Overdose: purpura and hemorrhage. Can cause anticoag skin necrosis.
Term
Heparin
Definition
Anti-coagulant. Overdose: purpura and hemorrhage. Can cause anticoag skin necrosis.
Term
Hydralazine
Definition
Vasodilator, used to treat HTN. Can cause autoimmunity (lupus).
Term
Hydrochlorthiazide
Definition
Thiazide diuretic. Overdose: gout symptoms. Also: Type 2 + 4 hypersensitivity reactions.
Term
Lithium
Definition
Used to treat manic-depression. Side effects: acne. Unmasking: acne, psoriasis.
Term
Methotrexane
Definition
Chemo. Side effects: alopecia = hair loss, gout symptoms. Unmasking: opportunistic infection. Also, can get erosions in skin. Can cause type 2 hypersensitivity.
Term
Orthotricyclin
Definition
Contraceptive/ estrogen + progesterone. Side effects: acne, melasma (avoid sun). Unmasking: acne. Idiosyncracy: porphyria cutanea tarda (PCT). Can cause druge induced erythema nodosum.
Term
Penicillin
Definition
Antibiotic. Unmasking: opportunisic overgrowth. Can cause allergic reactions (type 1-4). Can cause cell-mediated exanthematous eruption. Can cause AGEP.
Term
Phenobarbital
Definition
Barbituate/ anticonvulsant. Overdose: Coma blisters, hypotension, hypoxia, CNS and resp depression. Side effects: acne. Idiosyncracy: Acute intermittent prohpyria (AIP). Can cause DRESS. Can cause type 4 hypersensitivity. Can cause Steven johnson syndrome or TEN.
Term
Phenytoin
Definition
Anti-convulsant. Side effects: acne. Can cause type 2+4 hypersensitivity and autoimmunity. Can cause cell-mediated exanthematous eruption. Can cause DRESS. Can cause Steven Johnsons Syndrome, and TEN.
Term
Prednisone
Definition
Corticosteroid. Unmasking: opportunistic infection. Also, stimulates androgens: acne.
Term
Sulfonamides
Definition
= Sulfa drugs. Antibiotics and anticonvulsants. Unmasking: opportunistic overgrowth. Can cause type 2-4 hypersensitivity. Can cause DRESS. Can cause Steven Johnsons Syndrome, and TEN. Can cause druge induced erythema nodosum. Can cause cell-mediated exanthematous eruption.
Term
Tetracycline
Definition
Antibiotic. Unmasking: opportunistic overgrowth. Can cause AGEP.
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