Term
| Opportunistic Mycoses type of patients have what type of Diseases? |
|
Definition
| Leukemia/Diabetes/Underlying defect of immune system |
|
|
Term
| Opportunistic Mycoses type of patients are undergoing what type of treatments? |
|
Definition
| Corticosteroids/Cytotoxic drugs/Other agents |
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Term
| List 3 Reasons that would suggest a Opportunistic Mycoses MO of clinical significance |
|
Definition
Demonstrated microscopically in specimen
Repeatedly isolated
Normally sterile site |
|
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Term
| Are Most opportunists susceptible or resistant to cycloheximide? |
|
Definition
|
|
Term
True or False:
With Opportunistic Mycoses MOs you need to include media without antibiotics |
|
Definition
|
|
Term
|
Definition
Acquired by inhalation of spores
Fungus ball in lungs
Can disseminate |
|
|
Term
| Describe the Morphology of Asperigillus |
|
Definition
Narrow, septate, hyaline
Dichotomous brancing (45 degree angles)
"Closed Fist" |
|
|
Term
| What is the most common cause of Aspergillosis? |
|
Definition
|
|
Term
What are the following usually considered?
A. flavus
A. niger |
|
Definition
|
|
Term
True or False:
Penicillium is considered a common contaminant |
|
Definition
|
|
Term
True or False:
Penicillium rarely causes disease |
|
Definition
|
|
Term
| What is the disease that can be attributed back to Penicillium? |
|
Definition
|
|
Term
Which species of Penicillium is connected to the following:
Disseminated infection in AIDS patients (Asia) |
|
Definition
|
|
Term
| What is the morphology attributed to Penicillium? |
|
Definition
|
|
Term
| Is Zygomycosis considered a significant cause of disease? |
|
Definition
|
|
Term
| Where can Zygomycosis be found? |
|
Definition
| Worldwide on decaying vegetable material or in soil |
|
|
Term
| How are diseases usually acquired from Zygomycosis? |
|
Definition
| Inhalation of spores, infection follows |
|
|
Term
| What are the types of patients attributed to Zygomycosis? |
|
Definition
Uncontrolled diabetes
Prolonged therapy: corticosteroids/antibiotics/cytotoxins |
|
|
Term
| Describe the results of a Direct Exam of the Zygomycosis specimen with KOH |
|
Definition
Branching
Predominately nonseptate
Broad, irregular, ribbon-like hyphae |
|
|
Term
| What are the organisms called that cause Zygomycosis? |
|
Definition
|
|
Term
| Name the 3 Zygomycetes that were covered in lecture |
|
Definition
|
|
Term
| Which Zygomycetes is attributed to bread mold? |
|
Definition
|
|
Term
| Which Zygomycetes is attributed to the disease sometimes referred to as mucromycosis? |
|
Definition
|
|
Term
| Name the 4 Genera that are associated with Yeast like Fungi |
|
Definition
Candida
Cryptococcus
Torulopsis/Candida torulopsis
Trichosporon capitatum |
|
|
Term
| Which Yeast Like Fungi is considered Normal Flora of the Throat/Genitourinary tract/Skin? |
|
Definition
|
|
Term
| What are the 4 diseases associated with Candida albicans? |
|
Definition
Candidosis/Candidiasis(normal & immunocompromised)
Thrush
Vaginitis
Bronchopneumonia |
|
|
Term
| What are the 4 stains associated with a Direct Exam of Candida albicans? |
|
Definition
|
|
Term
| What is the cornmeal agar morphology associated with Candida albicans? |
|
Definition
| Chlamydospores, blastoconidia, pseudohyphae |
|
|
Term
| What is the cornmeal agar morphology associated with Candida other than albicans? |
|
Definition
| Pseudohyphae & blastoconidia |
|
|
Term
| What color will C. albicans appear on CHROMagar (TM) Candida? |
|
Definition
|
|
Term
| What color will C. tropicalis appear on CHROMagar (TM) Candida? |
|
Definition
| dark blue to metallic blue |
|
|
Term
| What color will C. krusei appear on CHROMagar (TM) Candida? |
|
Definition
| lavender with whitish border |
|
|
Term
| What is/are the disease(s) associated with Cryptococcus neoformans? |
|
Definition
Pulmonary/CNS
Very serious in immunocompromised
Meningitis |
|
|
Term
| What is the habitat associated with Cryptococcus neoformans? |
|
Definition
|
|
Term
| What is the halo formed during India Ink Prep due to? |
|
Definition
| Mucopolysaccharide capsule |
|
|
Term
| What is the Test of Choice for identifying Cryptococcus neoformans? |
|
Definition
| Antigen Detection (Latex beads coated with antibody) |
|
|
Term
| For Cryptococcus neoformans what type of media should be used? |
|
Definition
| Media without cycloheximide |
|
|
Term
| Phenol Oxidase Production is a test used to identify what MO? |
|
Definition
|
|
Term
Finish this line:
If the Antigen Detection Test is Positive, ____ ____ _ _____ |
|
Definition
|
|
Term
| Will Urea be + or = for Cryptococcus neoformans? |
|
Definition
|
|
Term
| What type of agar is used to determined Phenol Oxidase Production? |
|
Definition
| Birdseed agar (niger seed agar) |
|
|
Term
| What is another test used to identify Cryptococcus neoformans? |
|
Definition
| Carbohydrate utilization test |
|
|
Term
| How is Cryptococcus gattii transmitted? |
|
Definition
|
|
Term
| Where is Cryptococcus gattii usually found? |
|
Definition
|
|
Term
| What is so special about Cryptococcus gattii? |
|
Definition
| Infects healthy & immunocompromised hosts |
|
|
Term
| Which MO kills 25% of infected patients? |
|
Definition
|
|
Term
| What makes Pneumocystis jiroveci an atypical fungus? |
|
Definition
Cysts & Trophic Bodies
Does NOT grow in culture |
|
|
Term
| What does Pneumocystis jiroveci most commonly cause? |
|
Definition
|
|
Term
| Other than Pneumonia what other disease is attributed to Pneumocystis jiroveci and patients with AIDS? |
|
Definition
| Primary Opportunistic Infections |
|
|
Term
| What are the typical specimens for Pneumocystis jiroveci? |
|
Definition
Bronchoalveolar lavage
Transbronchial biopsy
Induced sputum |
|
|
Term
| Name 3/4 stains pointed out in lecture that are used to identify Pneumocystis jiroveci? |
|
Definition
Giemsa & GMS
Calcofluor white stain
Fluorescent monoclonal antibody stain |
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