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Exam 5 Nutritional Assessment
What We Need Unit 5 Lecture 2
100
Chemistry
Undergraduate 3
04/15/2015

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Term
Define the following:
Malnutrition
Definition
An imbalance and/or deficiency in one or more nutrients (proteins, fats, carbohydrates, vitamins, etc)
Term
What does Malnutrition cause a reduction in?
Definition
Organ muscle mass
Term
True or False:
Malnutrition affects every major organ function
Definition
True
Term
Some degree of malnutrition is present in what percent of ALL hospitalized patients?
Definition
30-50%
Term
What percent of elderly residents in long-term care facilities are affected by malnutrition?
Definition
50-85%
Term
True or False:
Malnutrition affects recovery from surgery and disease
Definition
True
Term
Define the following:
Kwashiorkor
Definition
Deficiency of protein; causes edema, rash, infections, fatigue, loss of muscle mass
Term
Define the following:
Marasmus
Definition
Deficiency of all calorie sources; chronic malnutrition/wasting, retardation
Term
Define/What can cause the following:
Chronic
Definition
long-term disease, poor food choices,
alcoholism, pregnancy, poverty,
homelessness
Term
Define/What can cause the following:
Acute
Definition
Disease, drug therapy, or depression
Term
What is Marasmus brought on by?
Definition
drought, natural disasters, political unrest, child abuse/neglect
Term
Which of the following has a 40% Death Rate:
Kwashiorkor Or Marasmus
Definition
Marasmus
Term
What is the term used to describe the following:
Need only small quantities per day
Definition
Micronutrients
Term
What is the term used to describe the following:
Needed in higher levels per day. Used for energy
Definition
Macronutrients
Term
What are some types of micronutrients?
Definition
Vitamins, minerals, and trace elements
Term
What are some types of macronutrients?
Definition
Carbohydrates, Proteins, Fats
Term
True or False:
Many vitamins act as enzyme cofactors in widespread cellular reactions
Definition
True
Term
What does a deficiency in vitamins result from?
Definition
poor diets, GI malabsorption diseases, liver dysfunction
Term
Which Vitamins are Fat Soluble?
Definition
A, D, E, K
Term
Which Vitamins are Water Soluble?
Definition
C, Folate, & Bs
Term
What is another name for Retinol?
Definition
Vitamin A
Term
What is another name for Vitamin A?
Definition
Retinol
Term
What are precursors of vitamin A?
Definition
Carotenes
Term
Carotenes are precursors of what vitamin?
Definition
Vitamin A
Term
What does a deficiency in Vitamin A cause?
Definition
night blindness, abnormal taste sensation, keratosis
Term
Vitamin A Toxicity leads to what?
Definition
Liver Failure
Term
What is Vitamin E?
Definition
Antioxidant
Term
What does Vitamin E do?
Definition
Protects RBC membranes from oxidant stress
Term
What does a deficiency in Vitamin E cause?
Definition
Hemolytic anemia and neurologic dysfunction
Term
Which Vitamin is Key in skeletal and teeth formation?
Definition
Vitamin D
Term
Which Vitamin is Necessary for calcium
& phosphate absorption and metabolism?
Definition
Vitamin D
Term
A Deficiency in Vitamin D causes what?
Definition
rickets (kids) and osteomalacia (adults)
Term
What does a Toxicity of Vitamin D cause?
Definition
Calcium deposits, renal and cardiac damage
Term
What Vitamin is needed for formation of prothrombin and 5 other coag factors?
Definition
Vitamin K
Term
What does a Deficiency of Vitamin K cause?
Definition
bleeding disorders and hemorrhagic episodes
Term
What may a deficiency of Vitamin K result from?
Definition
Antibiotic therapy
Term
What is used as an indicator of Vitamin K status?
Definition
PT/PTT
Term
Which vitamin is tied to the following:
Antioxidant, connective tissue
and collagen formation, cholesterol metabolism
Definition
Vitamin C
Term
What is another name for Vitamin C?
Definition
Ascorbic Acid
Term
What is another name for Ascorbic Acid?
Definition
Vitamin C
Term
What will a deficiency of Vitamin C cause?
Definition
Scurvy
Term
Describe scurvy
Definition
hemorrhages, bleeding gums, delayed wound healing
Term
What are the following considered:
Thiamine, riboflavin, pyridoxine
Definition
B Vitamins
Term
What do B Vitamins function as?
Definition
coenzymes and cofactors
Term
What B Vitamin Deficiency is becoming more common in alcoholics in the U.S.?
Definition
Beriberi - B1 Deficiency
Term
What is another name for B3?
Definition
Niacin
Term
What is another name for Niacin?
Definition
B3
Term
What is Niacin/B3 a component of?
Definition
NAD & NADP
Term
What is Niacin used in?
Definition
Respiration, lipid & glucose metabolism
Term
What does a deficiency in Niacin/B3 cause?
Definition
Pellagra
Term
Describe Pellagra
Definition
diarrhea, dementia, dermatitis, death
Term
What is another name for Vitamin B12?
Definition
Cobalamin
Term
What is another name for Cobalamin?
Definition
Vitamin B12
Term
Which Vitamin does the following describe:
Cobalt-containing compounds
Definition
Vitamin B12 / Cobalamin
Term
What is Vitamin B12 necessary for?
Definition
DNA Synthesis
Term
What does Vitamin B12/Cobalamin require for intestinal absorption?
Definition
Intrinsic factor(s)
Term
What does a Deficiency of B12/Cobalamin cause?
Definition
Pernicious Anemia
Term
Describe Pernicious Anemia
Definition
lack of, or antibodies against intrinsic factor
Term
What are characteristics of PA?
Definition
Megaloblastic changes in BM
Macro-ovalocytes, hypersegmented neutrophils
Dementia,
GI problems due to anaciditiy
Term
GI problems with PA are due to what?
Definition
Anacidity
Term
What happens to MCV, MCH, & MCHC in PA?
Definition
Increases
Term
What happens to H&H in PA?
Definition
Decreases
Term
What test is used for Vitamin B12/Cobalamin?
Definition
Schilling Test
Term
Describe the Schilling Test
Definition
Inability to absorb tagged B12 will result in low levels of tagged B12 in serum and urine
Term
True or False:
Vitamin B12/Cobalamin is sensitive to light
Definition
True
Term
What is Folate needed for?
Definition
DNA Synthesis and homocysteine metabolism
Term
What does a deficiency in Folate look like?
Definition
Megaloblastic anemia
Term
What are the 2 most common causes of Folate Deficiency?
Definition
Low intake (bad diet, alcoholism) and increased use (pregnancy)
Term
True or False:
Low levels of Folate during pregnancy may increase the risk of neural tube defects
Definition
True
Term
What does a deficiency of Folate cause?
Definition
Elevated homocysteine
Term
Elevated levels of homocysteine is considered a risk factor for what disease?
Definition
Cardiac disease
Term
What does Serum Folate indicate?
Definition
Circulating Levels
Term
What does RBC Folate indicate?
Definition
Folate stores
Term
True or False:
Folate is sensitive to light
Definition
True
Term
What are the following considered:
Iron, Iodine, Copper, Zinc
Definition
Trace Elements
Term
Where is most iron found in the body?
Definition
RBCs
Term
What is Iron stored as in the body?
Definition
Ferritin
Term
What is the most common anemia in the world?
Definition
IDA
Term
What are the 2 most common causes of IDA?
Definition
1. chronic blood loss
2. dietary insufficiency
Term
What does IDA look like under the microscope?
Definition
Microcytic
Hypochromic
Term
What happens to H&H with IDA?
Definition
Decreases
Term
What happens to MCV with IDA?
Definition
Decreases
Term
What happens to TIBC with IDA?
Definition
Increases
Term
What happens to Serum Fe and Ferritin with IDA?
Definition
Decreases
Term
What is the half life of Albumin?
Definition
20 days
Term
What is an indicator of long periods of malnutrition?
Definition
Albumin
Term
True or False:
Liver disease may alter albumin levels in the absence of malnutrition
Definition
True
Term
Low levels of Albumin in hospitalized patients results in what?
Definition
4x Morbidity
6x Mortality rates
Term
Levels of what protein marker may be useful in distinguishing kwashiorkor from marasmus?
Definition
Albumin
Term
In kwashiorkor what are the levels of albumin like?
Definition
Low
Term
In marasmus what are the levels of albumin like?
Definition
Normal
Term
What protein marker is a Major transport protein for T4 & Vitamin A
Definition
Prealbumin (transthyretin)
Term
What does prealbumin transport?
Definition
T4 & Vitamin A
Term
What protein marker is the BEST indicator of recent, short-term malnutrition and the effects of a feeding plan?
Definition
Prealbumin (transthyretin)
Term
What is the half life of Prealbumin?
Definition
1-2 days
Term
What protein marker is an Early indicator of iron deficiency?
Definition
Transferrin
Term
What protein marker is decreased in Nephrotic syndrome and Liver disease?
Definition
Transferrin
Term
What other biochemical marker reflects dietary fat intake?
Definition
Triglyceride
Term
What other biochemical marker is used for detection of malnutrition due to malabsorption?
Definition
Fecal Fat Analysis
Term
What are the following known as:
Glucose & HBA1C
Definition
Other Biochemical Markers
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