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Exam 5 Geriatric & Pediatric Laboratory Assessment
The Old and The Young Unit 5 Lecture 1
55
Chemistry
Undergraduate 3
04/15/2015

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Term
According to 2011 data from the CDC what was the leading cause of death in people 65 and older?
Definition
Heart Disease
Term
According to 2011 data from the CDC what was the 2nd leading cause of death in people 65 and older?
Definition
Cancer
Term
What "normal" changes are observed as you get older?
Definition
-Decline in total body water (dehydration) and muscle mass
-Increased lipids and adipose tissue
-Decline in lung, heart, liver, kidney, GI, immune and endocrine functions
Term
As Renal Function Decreases, what happens to the risk of toxicity?
Definition
Increases
Term
As Renal Function is reduced by half with patients who are 65 or older, what happens to GFR, CrCl, drug clearance?
Definition
Decrease; risk of toxicity
Term
What parts of the Lipids are increased with patients who are 65 or older?
Definition
Cholesterol & Tg
Term
As Cholesterol & Tg increase in patients who are 65 years or older, what does this raise the risk of?
Definition
Atherosclerosis & CHD
Term
What Liver Function parts decrease as you become older?
Definition
Albumin and protein
Term
As Renal Function is reduced by half with patients who are 65 or older, what happens to Plasma BUN, Cr and uric acid?
Definition
Increase
Term
With Liver Function what is the result of Drug detoxification as you get older?
Definition
Drugs/alcohol become more toxic
Term
With Liver Function, what happens to AST, ALT, ALP, GGT, LD as you get older?
Definition
Increase
Term
As you get older what happens to pO2?
Definition
Decreases
Term
As you get older what happens to pCO2?
Definition
Increases
Term
As pCO2 increases as you get older you become more susceptible to what?
Definition
Respiratory acidosis
Term
True or False:
Both Hyper- and hypothyroidism are common for patients who are 65 or older
Definition
True
Term
What happens to the following Endocrine Function as you get older:
Testosterone
Definition
Decreases (andropause)
Term
What happens to the following Endocrine Function as you get older:
Estrogen
Definition
Decreases (menopause)
Term
What happens to the following Endocrine Function as you get older:
GH
Definition
Decreases
Term
What happens to the following Endocrine Function as you get older:
Hypothalamus
Definition
Shrinks, causing dehydration among other things
Term
For patients who are 65 and older, what does a decrease in Estrogen increase the risk of?
Definition
Osteoporosis/CHD
Term
What happens to your Glucose Tolerance as you get older?
Definition
Declines
Term
What happens to the Prevalance of Type 2 Diabetes as you get older?
Definition
Increases
Term
When combined with high lipids, as you age, the risk of _____ increases x 20
Definition
AMI
Term
True or False:
Of the 28 conditions that the Arkansas newborn screening tests none can be cured
Definition
True
Term
True or False:
Of the 28 conditions that the Arkansas newborn screening tests none can be cured, but many can be controlled
Definition
True
Term
Match the following information to the disease:
Decreased T4 & Increased TSH
Cretinism
Definition
Congenital Hypothyroidism
Term
Match the following information to the disease:
Children 3 & under get a clinitest
Definition
Galactosemia
Term
Match the following information to the disease:
Phenylalanine Defect
Guthrie Bacterial Inhibition
Definition
PKU (phenylketonuria)
Term
Match the following information to the disease:
Elevated levels of immunoreactive trypsinogen
Definition
Cystic fibrosis
Term
What is immunoreactive trypsinogen (IRT)?
Definition
Enzyme secreted by the pancreas
Term
If the IRT is Positive, you should follow up with what?
Definition
Genetic testing and sweat chloride
Term
What do Birth trauma and RDS lead to?
Definition
respiratory acidosis and tissue hypoxia
Term
As Lactate Increases what happens to pCO2?
Definition
Increases
Term
As Lactate Increases what happens to pO2?
Definition
Decreases
Term
What is the leading cause of death in preemies?
Definition
RDS
Term
What is used as a predictor for pre-term delivery?
Definition
Fetal Fibronectin
Term
What is used to assess the source of jaundice in neonatal/pediatric patients?
Definition
Bilirubin
Term
Physiologic jaundice of the newborn - bilirubin levels should fall to adult levels by ____ ____
Definition
1 month
Term
What is the Rx for Physiologic jaundice of the newborn?
Definition
Phototherapy
Term
HDN (pathologic jaundice) is caused by what?
Definition
Overproduction of bilirubin from excess RBC lysis
Term
HDN is Mostly what kind of bilirubin
Definition
Unconjugated
Term
With HDN, there is a risk of what after birth?
Definition
Kernicterus
Term
What type of charts or tests would you perform to determine bilirubin levels in neonatal patients?
Definition
OD 450 / Liley Graph
Term
With Gestational Diabetes, what is there a risk of?
Definition
Insulin shock, RDS and macrosomia
Term
True or False:
Glucose levels in the newborn should be similar to adult levels
Definition
True
Term
What is the most prevalent type of diabetes in the pediatric population?
Definition
Type 1
Term
What is the most prevalent type of diabetes in the geriatric population?
Definition
Type 2
Term
Infantile diarrhea interferes with what elements absorption?
Definition
Calcium
Term
Infantile diarrhea interfering with Calcium absorption is consistent with what condition?
Definition
Neonatal tetany
Term
What element is always measured in cases of seizure of unknown origin?
Definition
Calcium
Term
What are the 2 Preanalytical concerns with pediatric patients?
Definition
Instruments may not accept pediatric collection tubes
Evaporation
Term
Neonatal/Pediatric:
Ammonia is tied to what condition?
Definition
Reye's Syndrome
Term
Neonatal/Pediatric:
Ammonia can lead to what?
Definition
Liver disease and encephalopathy
Term
Neonatal/Pediatric- Ammonia is tied to which of the following:
Metabolic acidosis
Metabolic alkalosis
Respiratory acidosis
Respiratory alkalosis
Definition
Metabolic alkalosis
Term
With the neonatal/pediatric population is Ammonia levels are not diagnosed in a timely manner than what can occur?
Definition
High Mortality
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