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first protein to try to turn into a drug therapy
used to treat genital herpes and Hep B and C and multiple sclerosis taking large doses of interferons can cause many side effects
help protect against abnormal cells so hoped it would be a cancer treatment. turned out on to effect some, and overall not very helpful |
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before modern medicine believed body had 4 humors humors were body fluids |
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Active Natural Acquired immunity |
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lymphocytes get activated. by disease like chicken pox party |
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Active Artificial Acquired Immunity |
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Passive Natural Acquired Immunity |
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get blood and remove clotting factors |
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know theres a specific antibody in that blood |
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Passive Artificial Acquired Immunity |
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Ig injection. growing antibodies in animals or getting them from people who have had the disease |
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Lymphocytes and antibodies are produced to eliminate foreign organisms, viruses or substances |
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Memory cells (lymphocytes) remain in body for protection against future exposure |
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Immunity is Acquired during an individual's lifetime |
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Recognition of self vs. non-self |
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Antigen "antibody generating" molecule |
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many small, specific regions on an Ag also called epitopes |
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grouping that only recognizes one epitope |
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group of antibodies that recognize the same protein. all three epitopes. |
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antibody made of 4 diff polypeptide chains. (quaternary structure) makes a Y |
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Five classes of Ab IgG: most abundant (80%) IgM: first produced Pentamer, with 10 Ag binding sites IgA: found in secretions, tissue surfaces IgE: mediates allergic response IgD: found on surface of B cells |
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molecules clumping to gether ex. tetanus toxin so it can't bind to neuromuscular junction. therefore neutralized/inactivated |
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