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Exam 4
Lecture 6 adn 7- random AD pharmcology
19
Aerospace Engineering
5th Grade
12/11/2013

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Term
when should memantine be perscribed?
why
Definition
in late sages of AD
-greatest effiacy is improving cogntiion or minimizing beahvior disturb
Term
since mementine MOa is diff form toher AD meds, what is another place in therapy for it?
Definition
in combo with cholinesterase inhibitors
Term
mementaine, how well does it work?
Definition
ther is small pop of responders, but when it works it works BIG to help functional and behavioral status
Term
*there are no characteristics to predict reposne to memantimine
Definition
Term
how long do you use memantine:?
Definition
case basis, only know effects short term but long term it cna be sueful to help behaviroal effects
Term
how do chol inhibtors make AD better?
Definition
slows progression
Term
how mnay ppl respong to chol inhibit
Definition
1/4 to 1/3
Term
when do you think a pt isnt repsonding to chol inhibitor
Definition
if decline at pre-tx rate 6 mo after drug therapy intitated
Term
due to 200 jouinral articel pointing out chol inhbitor may nto lead to less instutionalization formularies wanted to stop putitng them on- the things aginst this-
Definition
journal was underpowered
severity of cognition is not preidcitor of instituitionalization
cost effecigvenss only done with QALY
Term
*there are no predictors of response to chol inhibitors
Definition
Term
fro chol inhibitors, it is ont wheter to tx or not tx- it is whether to cont tx after 6 onths of trying it
Definition
Term
whihc chol inhibitor is best?
Definition
all are same
Term
if pt on other chol inhibitor, if becomes mod-sev do they ahve to swtich to Aricept?
Definition
no, can stay on other med evnen tho tis for mild-mod
Term
what is theraputic dose of donepezil?
Definition
5 mg
Term
how high do you push chol inhibiotrs
Definition
to max recocmended if possible
Term
*a lto fo time chol inhbitors start at initial dose and dont titrtae, this is what pharmacists can help with
Definition
Term
when d/c the chol inhbit take into effect can cause irreversible deffect loss, but also very expensive
Definition
Term
what is the counsel point on chol inhb and agitation
Definition
wait 4 wks, only then change to diff med if still have it
Term
ppl that get chronic chol inhibitors seems to have lower prevelance of beahviro problems
Definition
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