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the physical property of materials which return to their original shape after they are deformed |
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is measure of the tendency of a hollow organ to resist recoil toward its original dimensions upon removal of a distending or compression force |
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Very elactic Have large radii Not compliant |
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Not elactic Very complient Store blood volume |
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change of volume/ change in pressure |
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How much blood moves out of artery during systole? |
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small arteries resistance vessels local control of blood flow they are the major site of resistance |
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deliever blood to capillries have smooth muscle that consrict vasoconstriction and dilate vasodilation |
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Major roles of arterioles |
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1) Determine blood flow to organs 2) Determin MAP |
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Change in pressure/ resistance |
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Vasodilation and vasoconstriction are controlled by what two ways? |
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Local controls Extrinsic controls |
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mechanisms independent of nerves or hormones by which organs and tissues alter their own arerial reististances, thereby self - regulating their blood flows |
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Four ways of Local control of blood flow |
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1)Active hypermia 2)Flow autoregulation 3)Reactive hypermia 4)Response to injury (inflamation) |
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metabolizing tiusses causes arteriolar vasodilation due to increased need blood flow. Increased metabolic activity Metabolites: CO2, K, H, Adenosine, NO, bradykinin |
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intrinsic design to maintain constant blod flow despite changes in blood pressure. Stretch sensitive calicum channels allow direct responeses to change in vessel (myogenic response) |
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Following occulison (vessel completley block and no flow), short but dramatic increase in blood flow to organ/tissue. Due to lack of oxygen and build up of metabolites. Co2, H, Adenosine ex. tieing string around finger |
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Extrinci Blood flow that is NONCHOLINERGIC AND NONADRENERGIC |
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doesnt release neither norepinephrine or actylcholine but releas other vasodilator ex. NO (nitric oxide). Found mainly in enteric nervous system, GI tract, penis, clitoris. Basis for viagra and cialsis |
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Sympaththic stimulation of alpha adrnergic causes |
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Epinehrine stimulation of alpha - adrenergic receptors causes |
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Epinephrine stumlation of beta adrenergic receptors causes |
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Epineprhine Angiotensin II Vaopressin Atrial natiuretic peptide |
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binds to adrenergic receptors causes vasoconstriction or binds to beta adrenergic receptors (in GI tract and bladder) to cause vasodilation |
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Definition
vasoconstriction of arterioles |
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Atrial natruietic peptide |
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Definition
vasodilation of arterioles |
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The binding of which nerotransmitter can lead to both vasoconstriction and vasodilation |
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exchange of matierials, nutrients, metabolic end products, cell secretions, thin wall of endothelial cells suported by basal lamina. beds are found near almost every cell in body |
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have very slow velocity of blood flow allows nutrients to exchange effectively |
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Substances leave capillaries by which 3 mechanisms |
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Definition
1) Diffusion 2) Vesicular transport 3) Bulk flow |
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most effective. high to low gradient. oxygen and glucose enters tissues through capillaries. Co2 and wastes leave through capillaries |
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Communication, transport, protection |
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90% water 7% Proteins 3% Minerals |
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Na+ and Cl- provide osmotic equilibrium HCO3- major regulator of H+ in body fluids |
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albumin, globulins, fibrinogen |
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Which is the most abundant plasma protein |
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Definition
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Major functions of plasma protein |
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carriers for hormones, trace metals and drugs. proteoilysis of prohormones and enzyme precursors Inhibition of interstitial and plasm proteases Colloid pressure in plasma Body protection (Coagulation and Humoral Immunity) |
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first deflection atrial depolarization |
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second deflection ventricular depolarization |
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ventricular repolarization |
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What are the two stages in systole |
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1 Isovolumetric ventricular contraction 2 Ventricular ejection |
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heart relaxtion last twice as long |
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What are the two stages in diastole |
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1 Isovolumetric ventricular relaxtion 2 Ventricular filling |
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systemic more muscular pumps blood to the rest of the body |
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pulmonary; 100% of blood goes directly to lungs |
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